Results 161 to 170 of about 927,466 (317)

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Stain-free artificial intelligence-assisted light microscopy for the identification of leukocyte morphology change in presence of bacteria. [PDF]

Front Bioinform
Hunt A, Schulze H, Samuel K, Fisher RB, Bachmann TT.   +4 more
europepmc   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Immunohistochemical Characterization of the Immune Response in Chronic Endometritis Caused by <i>Chlamydia trachomatis</i>. [PDF]

Diagnostics (Basel)
Miranda-Maldonado I, Gopar-Cuevas Y, Álvarez-Cuevas S, Gallegos-Avila G, Ancer-Rodríguez J, Ortega-Martínez M, Jaramillo-Rangel G.   +6 more
europepmc   +1 more source

L’augmentation du pourcentage de lymphocytes Th17 est associée à un risque d’évolution vers une forme grave d’infection à SARS-CoV-2

, 2022
M. Samson, Barbara Nicolas, A Guilhem, Hélène Greigert, Marion Ciudad, Claudie Cladière, Cécile Straub, Mathieu Blot, Lionel Piroth, T. Rogier, H. Devilliers, Patrick Manckoundia, Thibault Ghesquière, S. Francois, Daniela Lakomy, Sylvain Audia, Bernard Bonnotte   +16 more
openalex   +2 more sources

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Phagocytosis of Lymphocytes and Erythrocytes by B-Cell Lymphoma in a Patient With a Clinical Suspicion of Pure Red Cell Aplasia. [PDF]

Clin Case Rep
Cao T, Li Y, Peng X.
europepmc   +1 more source

Acute, not Chronic, Exposure to Unpredictable Noise Periods Affects Splenic Lymphocytes and Plasma Corticosterone in the Mouse

, 1990
J Kugler, Karl Th. Kalveram, Katherine Lange   +2 more
openalex   +1 more source

WCN23-0711 The relationship between the ratio of neutrophil to lymphocyte and platelet to acute kidney injury associated with sepsis

, 2023
H. HONG, J. Jin, M. Li, J. Wang
openalex   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source