Results 21 to 30 of about 2,052,161 (361)

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

Journal of Immunology, 1992
During normal tissue remodeling, macrophages remove unwanted cells, including those that have undergone programmed cell death, or apoptosis. This widespread process extends to the deletion of thymocytes (negative selection), in which cells expressing ...
V. Fadok, D. Voelker, P. Campbell, J. Cohen, D. Bratton, P. Henson   +5 more
semanticscholar   +1 more source

Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]

, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

B lymphocytes secrete antigen-presenting vesicles

Journal of Experimental Medicine, 1996
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo, H. Nijman, W. Stoorvogel, R. Liejendekker, C. Harding, C. Melief, H. Geuze   +6 more
semanticscholar   +1 more source

Regulation of autoimmunity and donor cell engraftment by recipient Lyt-2+ cells during the graft-versus-host reaction. [PDF]

, 1987
When lymphocytes from DBA/2 mice are transferred to (C57BL X DBA/2)F1 (BDF1) mice, the ensuing graft-vs.-host reaction (GVHR) causes an autoimmune illness resembling human SLE.
Harper, SE, Roubinian, JR, Seaman, WE
core   +3 more sources

New immunolatex spheres: visual markers of antigens on lymphocytes for scanning electron microscopy [PDF]

, 1975
New immunochemical reagents consisting of antibodies bound to small latex spheres were used as visual markers for the detection and localization of cell surface antigens by scanning electron microscopy.
Dreyer, William J., Molday, Robert S., Rembaum, Alan, Yen, S. P. S.   +3 more
core   +2 more sources

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells [PDF]

, 1975
Vaccinia virus specific cytotoxicity against infected target cells was observed in vitro. Spleen lymphocytes from normal and immunized mice of the inbred strains C3H and DBA/2 were incubated with vaccinia virus-infected and non-infected 51Cr-labeled ...
Alkan, Boyum, Brunner, Calder, Cohen, Epstein, Evans, Fulginiti, Gardner, Gardner, Glasgow, Good, Hecht, Janossy, Julius, Koszinowski, Labowskie, Lohmann-Mathes, Lundstedt, Marker, McFarland, Oldstone, Perlmann, Perlmann, Profitt, Schirrmacher, Shearer, Shortman, Speel, Steele, Ueda, Ueda, Von Pirquet, Wagner, Wagner, Zinkernagel, Zinkernagel   +36 more
core   +1 more source

17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean, Adrian Tempescul, David Ternant, Anne Banet, Nathalie Douet-Guilbert, Anne Bordron, Boutahar Bendaoud, Hussam Saad, Mihnea Zdrenghea, Christian Berthou, Gilles Paintaud, Yves Renaudineau   +11 more
doaj   +1 more source

Crosstalk Between the Hepatic and Hematopoietic Systems During Embryonic Development

Frontiers in Cell and Developmental Biology, 2020
Hematopoietic stem cells (HSCs) generated during embryonic development are able to maintain hematopoiesis for the lifetime, producing all mature blood lineages.
Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Márcia Peixoto, Ana Cumano, Ana Cumano, Ana Cumano, Perpetua Pinto-do-Ó, Perpetua Pinto-do-Ó, Perpetua Pinto-do-Ó   +17 more
doaj   +1 more source

JAK Inhibitors and Oxidative Stress Control

Frontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras, Pinelopi Arvaniti, Pinelopi Arvaniti, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, George N. Dalekos, Kaliopi Zachou, Kaliopi Zachou, Anne Bordron, Yves Renaudineau, Yves Renaudineau   +11 more
doaj   +1 more source