Results 21 to 30 of about 927,466 (317)

Hematopoiesis: A Layered Organization Across Chordate Species

Frontiers in Cell and Developmental Biology, 2020
The identification of distinct waves of progenitors during development, each corresponding to a specific time, space, and function, provided the basis for the concept of a “layered” organization in development.
Ramy Elsaid, Ramy Elsaid, Ramy Elsaid, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Francisca Soares-da-Silva, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Marcia Peixoto, Dali Amiri, Dali Amiri, Dali Amiri, Nathan Mackowski, Nathan Mackowski, Nathan Mackowski, Pablo Pereira, Pablo Pereira, Pablo Pereira, Antonio Bandeira, Antonio Bandeira, Antonio Bandeira, Ana Cumano, Ana Cumano, Ana Cumano   +28 more
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STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau   +14 more
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Rheumatological features of Whipple disease

Scientific Reports, 2021
Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison, Pauline Preuss, Clémentine Leleu, François Robin, Adrien Le Pluart, Justine Vix, Guillaume Le Mélédo, Philippe Goupille, Elisabeth Gervais, Grégoire Cormier, Jean-David Albert, Aleth Perdriger, Béatrice Bouvard, Jean-Marie Berthelot, Nathan Foulquier, Alain Saraux, the network of rheumatologists from the Grand Ouest “VICTOR HUGO”   +16 more
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Pacific-Ciguatoxin-2 and Brevetoxin-1 Induce the Sensitization of Sensory Receptors Mediating Pain and Pruritus in Sensory Neurons

Marine Drugs, 2021
Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins.
Ophélie Pierre, Maxime Fouchard, Nelig Le Goux, Paul Buscaglia, Raphaël Leschiera, Richard J. Lewis, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +9 more
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Simulated patient and role play methodologies for communication skills and empathy training of undergraduate medical students

BMC Medical Education, 2020
Background Verbal and non-verbal communication, as well as empathy are central to patient-doctor interactions and have been associated with patients’ satisfaction. Non-verbal communication tends to override verbal messages.
Cristina Bagacean, Ianis Cousin, Anne-Helene Ubertini, Mohamed El Yacoubi El Idrissi, Anne Bordron, Lolita Mercadie, Leonor Canales Garcia, Jean-Christophe Ianotto, Philine De Vries, Christian Berthou   +9 more
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OVX836 Heptameric Nucleoprotein Vaccine Generates Lung Tissue-Resident Memory CD8+ T-Cells for Cross-Protection Against Influenza

Frontiers in Immunology, 2021
Tissue-resident memory (TRM) CD8+ T-cells play a crucial role in the protection against influenza infection but remain difficult to elicit using recombinant protein vaccines.
Judith Del Campo, Julien Bouley, Marion Chevandier, Carine Rousset, Marjorie Haller, Alice Indalecio, Delphine Guyon-Gellin, Alexandre Le Vert, Fergal Hill, Sophia Djebali, Yann Leverrier, Jacqueline Marvel, Béhazine Combadière, Florence Nicolas   +13 more
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Lymphocytic Adenohypophysitis and Lymphocytic Infundibuloneurohypophysitis.

Endocrine Journal, 1997
One hundred and twenty-four cases of lymphocytic adenohypophysitis have been reported since 1962. Nearly 60% of the cases in women involved inset of the disease in relation to pregnancy. Headache and visual field defects were the most frequent symptoms.
K, Hashimoto, T, Takao, S, Makino
openaire   +3 more sources

Combining cytogenetic and epigenetic approaches in chronic lymphocytic leukemia improves prognosis prediction for patients with isolated 13q deletion

Clinical Epigenetics, 2017
Background Both defective DNA methylation and active DNA demethylation processes are emerging as important risk factors in chronic lymphocytic leukemia (CLL).
Cristina Bagacean, Christelle Le Dantec, Christian Berthou, Adrian Tempescul, Hussam Saad, Anne Bordron, Mihnea Zdrenghea, Victor Cristea, Nathalie Douet-Guilbert, Yves Renaudineau   +9 more
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Intraepithelial lymphocytes [PDF]

Current Biology, 2017
Hoytema van Konijnenburg and Mucida discuss development and function of intraepithelial lymphocytes, which are found within the epithelial layer of mucosal and barrier tissues.
Hoytema van Konijnenburg, David P., Mucida, Daniel   +1 more
openaire   +3 more sources

17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean, Adrian Tempescul, David Ternant, Anne Banet, Nathalie Douet-Guilbert, Anne Bordron, Boutahar Bendaoud, Hussam Saad, Mihnea Zdrenghea, Christian Berthou, Gilles Paintaud, Yves Renaudineau   +11 more
doaj   +1 more source