Results 71 to 80 of about 1,988,114 (430)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Frontiers in Neurology, 2019 The brain is no longer considered an immune privileged organ and neuroinflammation has long been associated with Parkinson's disease. Accumulating evidence demonstrates that innate and adaptive responses take place in the CNS.
Marie Therese Fuzzati-Armentero +2 more
doaj +1 more source
IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer
British Journal of Cancer, 2015 Background:PD-L1 (programmed cell death 1 ligand 1) on tumour cells suppresses host immunity through binding to its receptor PD-1 on lymphocytes, and promotes peritoneal dissemination in mouse models of ovarian cancer.
K. Abiko +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Abnormal distribution of CD8 subpopulation in B-chronic lymphocytic leukemia identified by flow cytometry [PDF]
, 1988 We studied the occurrence of T-cell subpopulations for patients with B-cell chronic lymphocytic leukemia. The CD8+ population was divided into CD8+ suppressor (CD8a+) and CD8+ cytotoxic (CD8b+) lymphocytes using difference in orthogonal light scattering.\
B.G.De Grooth +30 more
core +2 more sources
T Lymphocytes Are Not Immune [PDF]
Molecular Therapy, 2013 Administration of genetically modified T lymphocytes to cancer patients has increased exponentially over the past 15 years, and these cells have been given to many hundreds of patients. These studies have often used retroviral vectors, and, in sharp contrast to clinical trials using hematopoietic stem cells as targets, gene-modified T cells have not ...
openaire +3 more sources
Lymphocyte Autophagy in Homeostasis, Activation, and Inflammatory Diseases
Frontiers in Immunology, 2018 Autophagy is a catabolic mechanism, allowing the degradation of cytoplasmic content via lysosomal activity. Several forms of autophagy are described in mammals.
Florent Arbogast +3 more
doaj +1 more source
Frontiers in Physiology, 2023 Methods: We examined whether immune cell profiles differ between healthy women (n = 38) and breast cancer survivors (n = 27) within 2 years of treatment, and whether any group-differences were influenced by age, cytomegalovirus infection ...
Ainhoa Arana Echarri +7 more
doaj +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
気管支肺胞洗浄液中リンパ球増多と患者年齢およびIgE系アレルギー反応との関連について [PDF]
, 1993 The proportion and number of lymphocytes in the airways were analyzed in 15 patients with a high proportion of lymphocytes in bronchoalveolar lavage (BAL) fluid (more than 30%) and in 17 patients with less than 20% of BAL lymphocytes. 1.
Kimura, Ikuro +4 more
core +1 more source