Results 81 to 90 of about 934,933 (319)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Age-related changes of apoptotic cell death in human lymphocytes

open access: yes, 2006
Apoptosis seems to be involved in immunosenescence associated with aging. Moreover, in lymphocytes (PBL) of patients with Alzheimer's disease, an increased susceptibility to the apoptotic pathway has been described possibly due to impaired protection of ...
Schindowski, Katharina   +3 more
core  

II. Detection of an antigen on resting T cells down-regulated after activation [PDF]

open access: yes, 1987
The expression of an antigen on porcine T lymphocytes detected by murine monoclonal antibody (mAb) 8/1 was investigated by functional studies and dual-parameter immunofluorescence.
Saalmüller, Armin   +4 more
core   +1 more source

Retrospective analysis of risk factors associated with mortality in hospitalized COVID-19 patients

open access: yesJournal of Family Medicine and Primary Care
Background Older age and comorbidities are associated with adverse outcomes in patients with coronavirus disease 2019 (COVID-19); however, comprehensive identification of mortality risk factors can further guide disease management.
Bijoya Chatterjee   +4 more
doaj   +1 more source

Dysregulatory Changes in the Lymphocytic Antiradical Defense System in Severe Concomitant Brain Injury

open access: yesОбщая реаниматология, 2007
Objective: to reveal the mechanisms of changes in the antioxidative defense system of the lymphocytes, spleen and thy-mus in severe brain injury.Materials and methods.
T. F. Sokolova   +4 more
doaj   +1 more source

CD₈⁺ AND CD₄⁺ REGULATORY T CELLS IN COLORECTAL CANCER

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2020
The pathogenesis of colorectal cancer (CRC) is closely associated with the development of an antitumor immune response. An important role in the regulation of the immune response is given to regulatory T cells (Treg), which may interfere with the ...
Galina Zhulai   +5 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Proton magnetic resonance spectroscopy of lymphocytes: An historical perspective

open access: yes, 1994
Proton magnetic resonance spectroscopy can be used to elucidate alterations to cellular chemistry associated with specific biological functions. It became apparent that this type of information was present in the magnetic resonance spectra from intact ...
Mountford, Carolyn E.   +1 more
core   +1 more source

Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]

open access: yes, 1990
Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Thomas   +4 more
core   +1 more source

Review on radiomic analysis in 18F-fluorodeoxyglucose positron emission tomography for prediction of melanoma outcomes

open access: yesCancer Imaging
Over the past decade, several strategies have revolutionized the clinical management of patients with cutaneous melanoma (CM), including immunotherapy and targeted tyrosine kinase inhibitor (TKI)-based therapies.
Karim Amrane   +8 more
doaj   +1 more source

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