Results 81 to 90 of about 897,225 (318)

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

CD19+ B-Cells, a New Biomarker of Mortality in Hemodialysis Patients

Frontiers in Immunology, 2018
Background and objectivesMortality of patients on hemodialysis (HD) remains very high despite recent improvements in HD techniques. Cardiovascular (CV) complications and infections are the main causes of death.
María Molina, Luis M. Allende, Luis E. Ramos, Eduardo Gutiérrez, Daniel E. Pleguezuelo, Eduardo R. Hernández, Francisco Ríos, Cristina Fernández, Manuel Praga, Manuel Praga, Enrique Morales   +10 more
doaj   +1 more source

Re-utilization of Lymphocytes in Lymphopoiesis [PDF]

, 1957
O. A. Trowell
openalex   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source

Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic

Frontiers in Immunology, 2019
Cetacean morbillivirus (CeMV; Paramyxoviridae) causes epizootic and interepizootic fatalities in odontocetes and mysticetes worldwide. Studies suggest there is different species-specific susceptibility to CeMV infection, with striped dolphins (Stenella ...
Josué Díaz-Delgado, Kátia R. Groch, Rodrigo Ressio, Isis P. J. Riskallah, Isis P. J. Riskallah, Eva Sierra, Simona Sacchini, Óscar Quesada-Canales, Manuel Arbelo, Antonio Fernández, Elitieri Santos-Neto, Joana Ikeda, Rafael Ramos de Carvalho, Alexandre de Freitas Azevedo, Jose Lailson-Brito, Leonardo Flach, Cristina T. Kanamura, Natália C. C. A. Fernandes, Bruno Cogliati, Cinzia Centelleghe, Sandro Mazzariol, Ludovica Di Renzo, Gabriella Di Francesco, Giovanni Di Guardo, José Luiz Catão-Dias   +24 more
doaj   +1 more source

ACTION OF SERUM ON LYMPHOCYTES IN VITRO [PDF]

, 1923
Alexis Carrel, Albert H. Ebeling
openalex   +1 more source

SensRORing cholesterol to drive protumoral myelopoiesis

Molecular Oncology, EarlyView.
Bleve et al. uncover a cholesterol‐driven immune evasion pathway, where RORγ‐dependent myelopoiesis shapes tumor immunosuppression. Targeting RORγ and PCSK9 emerges as a strategy to boost cancer immunotherapy. Protumoral myelopoiesis is a determinant of immunoevasion and tumor spread in many malignancies.
Sara Gennari, Luigi Nezi, Teresa Manzo
wiley   +1 more source

MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals

Genetics and Molecular Biology, 2009
Chromosomal translocations are characteristic of hematopoietic neoplasias and can lead to unregulated oncogene expression or the fusion of genes to yield novel functions.
María Sol Brassesco, Ana Paula Montaldi, Diana Ester Gras, Rosane Gomes de Paula Queiroz, Nilce Maria Martinez-Rossi, Luiz Gonzaga Tone, Elza Tiemi Sakamoto-Hojo   +6 more
doaj   +1 more source

THE EFFECT OF PILOCARPINE ON THE OUTPUT OF LYMPHOCYTES THROUGH THE THORACIC DUCT [PDF]

, 1908
F. Peyton Rous
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source