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Tim-3 Is Required for Regulatory T Cell-Mediated Promotion of T Cell Exhaustion and Viral Persistence during Chronic Lymphocytic Choriomeningitis Virus Infection. [PDF]
Nieves-Rosado HM +11 more
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Lymphocytic Choriomeningitis Virus RNAs
Nature New Biology, 1971IT has been proposed that lymphocytic choriomeningitis (LCM) virus and immunologically related viruses should be placed in a new taxonomic group, with LCM virus as the prototype virus1,2. They were called arenoviruses because they contain, as a unique feature, electron-dense, sand-like or ribo-some-like granules2.
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Congenital lymphocytic choriomeningitis virus: A review
Prenatal Diagnosis, 2022AbstractIntroductionLymphocytic choriomeningitis virus (LCMV) uses rodents such as mice and hamsters as its principal reservoir. When women acquire LCMV during pregnancy because of contact with rodents, it can lead to congenital LCMV infection, which is associated with high mortality and morbidity.
Lucile Pencole +5 more
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Lymphocytic Choriomeningitis Virus
2018Lymphocytic choriomeningitis virus is a rodent-borne virus that is an uncommon cause of congenital infection. Affected infants present with brain and eye lesions, including periventricular calcifications, neuronal migration defects, and chorioretinitis.
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Lymphocytic Choriomeningitis Virus
1989Of all the families of viruses, it is tempting to say that none but the arenaviruses has brought to light so many principles on which modern-day viral immunobiology and viral immunopathology are based. The touchstone, and prototype of the Arenaviridae, is murine lymphocytic choriomenigitis virus (LCMV).
Daniel C. Pevear, Charles J. Pfau
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Congenital Lymphocytic Choriomeningitis Virus Infection
Archives of Pediatrics & Adolescent Medicine, 1996Lymphocytic choriomeningitis virus (LCMV), an arenavirus perpetuated by chronic infection of mice, has been the agent of sporadic and epidemic disease in Europe and the Americas. Postnatal acquisition of LCMV may be inapparent or associated with systemic or central nervous system manifestations. Congenital LCMV infection, first recorded in England more
L L, Barton +3 more
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Animal Models Using Lymphocytic Choriomeningitis Virus
Current Protocols in Immunology, 2000AbstractThis unit includes protocols for inducing systemic infection and persistent infection of mice with lymphocytic choriomeningitis virus (LCMV). Methods used to measure T cell responses to LCMV are then described. A protocol to assess anti‐LCMV immunity in vivo is also included. Support protocols for preparing LCMV stocks and measuring LCMV titers
M, von Herrath, J L, Whitton
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Lymphocytic choriomeningitis virus: Emerging fetal teratogen
American Journal of Obstetrics and Gynecology, 2002Lymphocytic choriomeningitis virus (LCMV), a rodent-borne arenavirus, is an often undiagnosed human fetal teratogen. We describe a neonate born with hydrocephalus and chorioretinitis after maternal second-trimester symptomatic LCMV infection. Previously reported affected infants are reviewed.
Leslie L, Barton +2 more
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Immune conflicts in lymphocytic choriomeningitis virus
Springer Seminars in Immunopathology, 1995In this chapter, we have reviewed the immunopathology of LCMV disease and the possible mechanisms involved. While much of what has been learned about LCMV immunopathology is unique to this system, many of the basic principles can be used to increase our understanding of viral immunopathology in other systems.
M S, Asano, R, Ahmed
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