Results 101 to 110 of about 154,837 (273)

Anti‐Inflammatory Effects of Punicic Acid and Its Molecular Mechanisms in RAW264.7 Cells and Zebrafish

open access: yesFood Safety and Health, EarlyView.
Punicic acid (PA) was enriched and purified from PSO by molecular distillation with significant anti‐inflammatory activity to RAW264.7 cells, as well as to zebrafish. Anti‐inflammatory mechanism involved regulating NF‐κB and MAPK signaling pathways. ABSTRACT Punicic acid (PA) is the main fatty acid in pomegranate seeds, which shows multiple biological ...
Mengqi Zhang   +8 more
wiley   +1 more source

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka   +9 more
wiley   +1 more source

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

open access: yesiNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang   +7 more
wiley   +1 more source

Inflammatory Bowel Disease with Cytoplasmic-Staining Antineutrophil Cytoplasmic Antibody and Extensive Colitis

open access: yesCanadian Journal of Gastroenterology, 1998
A cohort of 18 patients with inflammatory bowel disease who were characterized by the presence of cytoplasmic-staining antineutrophil cytoplasmic antibody (cANCA) and extensive colitis is reported.
Hugh James Freeman
doaj   +1 more source

Lymphocytic Colitis Associated with Lansoprazole Treatment

open access: yesCurrent Therapeutic Research, 2007
There have been several reported cases of lansoprazole-associated collagenous colitis (CC) reported in the literature but only 1 reported case of lansoprazole-associated lymphocytic colitis (LC) in the literature. Both CC and LC are considered inflammatory bowel diseases, but they are distinctly classified based on the condition of the colon, which is ...
Alagozlu, Hakan   +3 more
openaire   +3 more sources

[An Unusual Cause of Chronic Diarrhea - Lymphocytic Colitis]

open access: yes, 1994
We report a case of lymphocytic colitis in a 74-year-old woman presenting with watery diarrhea since 1 year and in whom previous extensive investigations were normal.
Lagneaux, G.   +5 more
core  

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Diagnosis and management of microscopic colitis

open access: yesThe Saudi Journal of Gastroenterology, 2006
Microscopic colitis (MC) in both of its forms, collagenous and lymphocytic colitis, is considered now an important cause of diarrhea in middle aged and elderly patients.
Al Malki Ahmad
doaj  

Long‐Term Outcomes of Low‐Dose Steroid Induction for Autoimmune Pancreatitis: A Multicenter Retrospective Study Identifying Risk Factors for Relapse

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Steroids are the first‐line treatment for autoimmune pancreatitis (AIP); however, the impact of lower initial doses on relapse remains unclear. Methods Ninety patients were divided into high‐dose (HD; > 0.4 mg/kg/day) and low‐dose (LD; ≤ 0.4 mg/kg/day) induction groups. The treatment response, relapse rate, and predictors of relapse
Yuhei Iwasa   +9 more
wiley   +1 more source

Lymphocytic Gastritis in a Patient With Microscopic Colitis: A Case Report

open access: yes
Lymphocytic gastritis (LG) is a rare form of gastritis characterized by lymphocytosis in the gastric mucosa, while microscopic colitis (MC) is the chronic inflammatory disease of the large intestine with lymphocytic or collagenous colitis as two distinct
Estrella, Jewel   +5 more
core   +1 more source

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