Results 111 to 120 of about 154,837 (273)

Immunohistochemical localization of the EP4 receptor in lymphocytic colitis tissues.

, 2013
A. Normal control colon demonstrating EP4 staining (blue arrow) localized to the surface of intestinal and crypt (yellow arrow) epithelial cells. B and C. Lymphocytic colitis tissues showing increased EP4 expression on surface intestinal epithelial cells
Indranil Dey (301630), Paul L. Beck (319031), Kris Chadee (249039)   +2 more
core   +1 more source

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti‐tumor necrosis factor alpha therapy in children

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in pediatric inflammatory bowel disease (PIBD) with biologics, remission rates remain at 47%–60% with loss‐of‐response rates at 60%–68%. Evidence for efficacy of dual biologic therapy (DBT) with anti‐tumor necrosis factor alpha therapy (anti‐TNF‐α)‐ vedolizumab (VDZ) for children refractory to anti‐TNF‐α therapy is ...
Jonathan E. M. O'Donnell, Carlie Bolles, Claire R. Reilly, Manal Morgan, Christopher Burgess, Fariha Balouch, Peter J. Lewindon   +6 more
wiley   +1 more source

The genetic landscape of congenital diarrheas and very early onset inflammatory bowel disease in the Middle East

JPGN Reports, EarlyView.
Abstract Objectives Monogenic causes of congenital diarrheas and enteropathies (CoDE) and very early onset inflammatory bowel disease (VEOIBD) are mostly recessive and therefore more prevalent in populations with increased consanguinity rates. To assess the genetic basis of these disorders in a likely high‐prevalence population, we established a multi ...
Lily Gillette, Muna Al Safar, Ganeshwaran H. Mochida, Casey Johnson, Stephen Babcock, Klaus Schmitz‐Abe, Michael Field, Jessica Yang, Richelle Bearup, Ahmed Megahed, Mohammed Ezz El Regal Abbas, Tarek Baraket, Sherine Elziny, Ali Sobh, Gulin Eren, Fawaz AlRefaee, Rana Bitar, Mohamed Miqdady, Pankaj B. Agrawal, Scott B. Snapper, Jay R. Thiagarajah, Jodie Ouahed   +21 more
wiley   +1 more source

Lymphocytic colitis in a child with non-responsive celiac disease

, 2008
In celiac disease, symptoms usually improve with strict adherence to diet. Some patients however do not show improvement despite of diet therapy. We here report a girl with non-responsive celiac disease whose diarrhea did not improve despite of a gluten ...
Soylu, O. Bekem, ÖZTÜRK, YEŞİM, ÖZER, ERCAN   +2 more
core  

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research [Elektronisk resurs]

Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis.
Münch, Andreas, Münch, Andreas,, Escudero-Hernandez, Celia,, Escudero Hernández, Celia, Escudero-Hernandez, Celia   +4 more
core   +1 more source

Pediatric hereditary angioedema presenting as recurrent episodic abdominal pain and vomiting: Challenges in diagnosis and management

JPGN Reports, EarlyView.
Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche, Jhoanna Valery Adauto Luizaga, Maria Soledad Arcucci, Claudio Alberto Salvador Parisi, Judith Cohen Sabban, Agustina Venditti, Valentina Riveros, Giancarlo Testa, Veronica Busoni   +8 more
wiley   +1 more source

Human immunodeficiency virus infection mimicking very early onset inflammatory bowel disease

JPGN Reports, EarlyView.
Abstract Very early onset inflammatory bowel disease (VEO‐IBD), defined as diagnosis before 6 years of age, is often associated with immune dysregulation and monogenic etiologies; however, infectious mimics may be overlooked in low‐prevalence regions. We report a 4‐year‐old male with poor weight gain, intermittent diarrhea, elevated fecal calprotectin,
Rasha Abi Radi Abou Jaoudeh, Cary Sauer, Teresa Oh   +2 more
wiley   +1 more source

Collagenous gastritis in pediatric patients with severe follicular pangastritis and iron deficiency anemia

JPGN Reports, EarlyView.
Abstract Collagenous gastritis is a rare disorder characterized by subepithelial collagen deposition in the gastric mucosa and is frequently associated with iron deficiency anemia. We report two girls aged 8 and 16 years with persistent iron deficiency anemia, abdominal pain, bloating, and constipation.
María Juliana Rusinque Del Busto, Karina Lozano Rivera, Maira Alejandra Forero Rivera, Alejandra Calderón, Santiago Walker, Angie Vergara Espitia, José Fernando Vera Chamorro   +6 more
wiley   +1 more source

Collagenous Colitis - Jejunal and Colorectal Pathology

, 1992
Aims: To determine: (1) whether there is an association between collagenous colitis and coeliac disease or lymphocytic colitis; (2) the distribution of lymphocyte subsets and macrophages in the lamina propria and surface epithelial layer in collagenous ...
Bhathal, PS, Armes, J, Schroeder, W, Gee, DC, Macrae, FA   +4 more
core   +1 more source

Vedolizumab use for severe chronic enterocolitis in a child with Hoyeraal–Hreidarsson syndrome: A case report

JPGN Reports, EarlyView.
Abstract We report a patient with Hoyeraal–Hreidarsson syndrome (HHS), a telomere biology disorder, who developed severe chronic enterocolitis with inflammatory bowel disease‐like features. Vedolizumab led to improvement in stool frequency, reduced fecal calprotectin, and clinical remission without infectious complications.
Yasutaka Chiba, Manabu Takahashi, Taro Yoshida, Seiya Tagane, Takeshi Shiohata, Shoko Miura, Manami Akasaka   +6 more
wiley   +1 more source