Results 31 to 40 of about 154,837 (273)

Management of microscopic colitis: challenges and solutions

Clinical and Experimental Gastroenterology, 2019
Julia Shor,1 Gustavo Churrango,1 Nooshin Hosseini,2 Christopher Marshall1 1Department of Gastroenterology, University of Massachusetts Medical School, Worcester, MA, USA; 2Department of Gastroenterology, Mount Sinai Hospital, New York, NY, USA Abstract ...
Shor J, Churrango G, Hosseini N, Marshall C   +3 more
doaj   +1 more source

Serotonin in the Pathogenesis of Lymphocytic Colitis. [PDF]

J Clin Med, 2021
Lymphocytic colitis (LC) is a chronic inflammatory disease associated with watery diarrhea, abdominal pain, and colonic intraepithelial lymphocytosis. Serotonin (5-hydroxytryptamine, 5-HT) is reported to increase in certain colon diseases; however, little is known regarding its metabolism in LC.
Chojnacki C, Popławski T, Gasiorowska A, Chojnacki J, Blasiak J.   +4 more
europepmc   +6 more sources

Lymphocytic colitis: pathologic predictors of response to therapy

Human Pathology, 2018
Although the presence of intraepithelial lymphocytosis with surface epithelial damage is a unifying feature of lymphocytic colitis, there are nonclassical features that create morphologic heterogeneity between cases. Limited data on the significance of these secondary histologic features are available.
Setia, Namrata, Alpert, Lindsay, van der Sloot, Kimberley W. J., Colussi, Dora, Stewart, Kathleen O, Misdraji, Joseph, Khalili, Hamed, Lauwers, Gregory Y   +7 more
openaire   +3 more sources

Microscopic Colitis in Patients with ‎Unexplained Chronic Watery non-‎Bloody Diarrhea: A Cross Sectional ‎Study‎ ‎ [PDF]

Afro-Egyptian Journal of Infectious and Endemic Diseases, 2022
Background and study aim: Microscopic colitis is an increasingly recognized cause of chronic watery non-bloody diarrhea. ‎The diagnosis of microscopic colitis is mainly based on pathological examination of colonic ‎biopsy from patients with chronic ...
Sameh Abdel Monem, Ahmed Sharaf, Mohamed Alabiad, Ibrahim Ibrahim   +3 more
doaj   +1 more source

Lymphocytic colitis can be transcriptionally divided into channelopathic and inflammatory lymphocytic colitis. [PDF]

United European Gastroenterol J
AbstractBackgroundThe pathobiology of the non‐destructive inflammatory bowel disease (IBD) lymphocytic colitis (LC) is poorly understood. We aimed to define an LC‐specific mucosal transcriptome to gain insight into LC pathology, identify unique genomic signatures, and uncover potentially druggable disease pathways.MethodsWe performed bulk RNA ...
Bhardwaj A, Münch A, Montague J, Koch S, Rosenstiel P, Escudero-Hernández C.   +5 more
europepmc   +5 more sources

SARS-CoV-2-triggered lymphocytic colitis. [PDF]

BMJ Case Rep, 2021
The ability of SARS-CoV-2 to infect the gastrointestinal tract is well described. Inflammatory bowel diseases (IBD) are believed to represent a disorganised immune response in genetically predisposed individuals, which are triggered by various ...
Nassar IO, Langman G, Quraishi MN, Sharma N.   +3 more
europepmc   +2 more sources

Concomitant Lymphocytic Colitis With Recurrent Clostridium difficile Infection. [PDF]

Cureus
Microscopic colitis is a clinicopathological diagnosis that is characterized by chronic microscopic inflammation of the colon and presents with chronic watery diarrhea.
Suleiman NM, Baiyasi M, Al-Saghir T, Daines B, Patel F.   +4 more
europepmc   +2 more sources

Pralsetinib-Induced Lymphocytic Colitis. [PDF]

ACG Case Rep J
ABSTRACT Lymphocytic colitis (LC) is a subtype of microscopic colitis, often associated with chronic watery diarrhea and characterized by an increase in intraepithelial lymphocytes. Although various medications are implicated in drug-induced LC, its incidence as a treatment-related adverse effect of rearrangement during transfection ...
Jin MF, Tawfic SS, Wang XJI.
europepmc   +3 more sources

Paucicellular and Asymptomatic Lymphocytic Colitis Expanding the Clinicopathologic Spectrum of Lymphocytic Colitis [PDF]

American Journal of Clinical Pathology, 2004
We examined clinicopathologic associations and biopsy changes that suggested classic lymphocytic colitis (C-LC) but were less well developed in intensity or distribution in 19 cases, which we termed paucicellular LC (P-LC). We also studied clinicopathologic associations and prevalence of LC in 100 asymptomatic, non-gluten-sensitive adults who underwent
Neal S, Goldstein, Punam, Bhanot
openaire   +2 more sources

Interventions for treating lymphocytic colitis. [PDF]

Cochrane Database Syst Rev, 2017
Lymphocytic colitis is a cause of chronic diarrhea. It is a subtype of microscopic colitis characterized by chronic, watery, non-bloody diarrhea and normal endoscopic and radiologic findings. The etiology of this disorder is unknown.Therapy is based mainly on case series and uncontrolled trials, or by extrapolation of data for treating collagenous ...
Chande N, Al Yatama N, Bhanji T, Nguyen TM, McDonald JW, MacDonald JK.   +5 more
europepmc   +4 more sources