Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. [PDF]
, 2017 Haematopoiesis is an essential process in early vertebrate development that occurs in different distinct spatial locations in the embryo that shift over time.
Aggio, Julian +6 more
core +1 more source
Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering
Advanced Healthcare Materials, EarlyView.This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer +4 more
wiley +1 more source
Metabolic regulation by prostaglandin E 2 impairs lung group 2 innate lymphoid cell responses [PDF]
, 2021 Calum T. Robb +13 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente +5 more
wiley +1 more source
Embryonic thermal manipulation improved early immunity in broiler chickens
Frontiers in PhysiologyImmunity in chickens is age-dependent and develops gradually over time. The initial defense by the host is a crucial mechanism for combating microbial infections. Embryonic thermal manipulation (TM) represents a promising approach for sustainable broiler
Sadid Al Amaz +5 more
doaj +1 more source
CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]
, 2017 Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya +58 more
core +3 more sources
Acute Epstein–Barr virus positive cytotoxic T/Nature Killer cell lymphoid hyperplasia (AEBV+CT/NK-LH) mimicking natural killer/T cell lymphoma [PDF]
, 2023 Yanlin Zhang +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]
, 2011 Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Agirre, Xabier +34 more
core