Results 71 to 80 of about 385,081 (259)

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi, A Fortin, A Kahnert, A Mantovani, AM Becker, Anna Giagu, Antonio Giovanni Anfossi, CY Chen, DM Carragher, DM Lowe, E Corsiero, Elisabetta Antuofermo, F Mattei, Fabrizio Mattei, Filippo Belardelli, G Delogu, G Schiavoni, Giovanna Schiavoni, Giovanni Delogu, Giovanni Fadda, HP Gideon, Ivana Palucci, JF Marquis, JG Egen, JL Flynn, K Turcotte, K Turcotte, KB Urdahl, KK Huynh, L Gabriele, L Guglani, L Ramakrishnan, Laura Abalsamo, Lucia Gabriele, M Behr, M Munder, M Sali, Massimo Sanchez, MC Tsai, ME El Shikh, Michela Sali, MP Berry, NA Giese, Olivier Neyrolles, P Tailor, PJ Maglione, RL Hunter, S Hambleton, S Kunnath-Velayudhan, SA Luther, SS Kashino, Stefano Rocca, SY Foo, T Holtschke, T Ulrichs, TA Day, TD Randall, X Zhou, Y Yoshikai   +58 more
core   +3 more sources

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Isolation, phenotype, and allostimulatory activity of mouse liver dendritic cells [PDF]

, 1994
Donor liver-derived dendritic cells (DC) have recently been identified within various lymphoid and nonlymphoid tissues of organ allograft recipients, including nonimmunosuppressed mice transplanted with and permanently accepting major histocompatibility ...
Li, Y, Lu, L, Rao, AS, Starzl, TE, Subbotin, V, Thomson, AW, Woo, J   +6 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Structural changes in the lacrimal sac epithelium and associated lymphoid tissue during experimental dacryocystitis

Clinical Ophthalmology, 2011
Makoto Ishikawa1, Masabumi Kubo2, Seiji Maeda3, Yu Sawada1, Eiichi Uchio4, Takeshi Yoshitomi11Department of Ophthalmology, Akita University School of Medicine, Akita, Japan; 2Fukiage Eye Clinic, Hachinohe, Japan; 3Maeda Eye Clinic, Honjo, Japan ...
Yoshitomi T, Uchio E, Sawada Y, Maeda S, Kubo M, Ishikawa M   +5 more
doaj  

Microchimerism, dendritic cell progenitors and transplantation tolerance [PDF]

, 1995
The recent discovery of multilineage donor leukocyte microchimerism in allograft recipients up to three decades after organ transplantation implies the migration and survival of donor stem cells within the host.
Demetris, AJ, Lu, L, Murase, N, Rao, AS, Starzl, TE, Thomson, AW   +5 more
core   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Cytokine Networks between Innate Lymphoid Cells and Myeloid Cells

Frontiers in Immunology, 2018
Innate lymphoid cells (ILCs) are an essential component of the innate immune system in vertebrates. They are developmentally rooted in the lymphoid lineage and can diverge into at least three transcriptionally distinct lineages.
Arthur Mortha, Kyle Burrows
doaj   +1 more source

Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. [PDF]

, 2020
Purpose of review:This review summarizes recent literature defining tissue-resident memory T cells (TRM) and discusses implications for HIV pathogenesis, vaccines, and eradication efforts.Recent findings:Investigations using animal models and human ...
Ferre, April L, Kiniry, Brenna E, Shacklett, Barbara L   +2 more
core  

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis [PDF]

, 2016
MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with ...
Alivernini, Stefano, Benvenuto, Roberta, Canestri, Silvia, Di Mario, Clara, Elmesmari, Aziza, Fedele, Anna Laura, Ferraccioli, Gianfranco, Gigante, Maria Rita, Gremese, Elisa, Kurowska-Stolarska, Mariola, Mangoni, Antonella, McInnes, Iain B., Petricca, Luca, Tolusso, Barbara   +13 more
core   +2 more sources