Results 51 to 60 of about 35,966 (245)
Clinical Pharmacology &Therapeutics, Volume 118, Issue 4, Page 917-927, October 2025.Tocilizumab dosing for management of T cell‐engaging bispecific antibody‐related CRS in patients with R/R B‐cell NHL. The recent surge in T‐cell‐engaging and chimeric antigen receptor (CAR) T‐cell therapies is changing the landscape of cancer therapy.
Candice Jamois +13 more
wiley +1 more source
Present and future of allogeneic natural killer cell therapy
Frontiers in Immunology, 2015 Natural killer (NK) cells are innate lymphocytes that are capable of eliminating tumor cells and are therefore used for cancer therapy. Although many early investigators used autologous NK cells, including lymphokine-activated killer cells, the clinical ...
Okjae eLim +3 more
doaj +1 more source
The LIN28B–let‐7–PBK pathway is essential for group 3 medulloblastoma tumor growth and survival
Molecular Oncology, 2023 Children with Group 3 medulloblastoma (G3 MB) have a very poor prognosis, and many do not survive beyond 5 years after diagnosis. A factor that may contribute to this is the lack of available targeted therapy.
Shubin W. Shahab +12 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 BackgroundSkin cancer is one of the most commonly diagnosed cancers worldwide. The 5-year survival rate of the most aggressive late-stage skin cancer ranges between 20 and 30%. Thus, the discovery and investigation of novel target therapeutic agents that
Xiaorong Fu +20 more
doaj +1 more source
Ultra‐Processed Foods and Markers of Systemic Inflammation in Children
Food Science &Nutrition, Volume 13, Issue 9, September 2025.Illustration showing the association between ultra‐processed foods intake and systemic inflammation, measured with cytokines levels in children. ABSTRACT Diets high in ultra‐processed foods (UPF) have been associated with negative health outcomes in adults; however, UPF's impact on children's health and their underlying mechanisms remain underexplored,
Camila Awad +8 more
wiley +1 more source
Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]
, 1986 Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA +6 more
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Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source
Asthma in Children and Adults: A Shared Biological and Molecular Basis
Canadian Respiratory Journal, 1995 The objective of this paper is to describe the important clinical, physiological, immunological and biological similarities among asthmatic infants, children and adults. A comparison of the reported clinical presentation, physiological changes, histology
Paolo M Renzi
doaj +1 more source
Molecular Mechanisms of Chronic Pain and Therapeutic Interventions
MedComm, Volume 6, Issue 8, August 2025.We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li +8 more
wiley +1 more source
A Review: Can Cytokines Induce Vascular Inflammation as a Sequela of Viral Infections?
Health Science Reports, Volume 8, Issue 7, July 2025.ABSTRACT Background and Aim There are many unknown consequences of viral infections. In this piece, we looked at one of these effects that influence the venous system of the body, vasculitis, an inflammation of the blood vessels. Discussion The study illustrates that viral infections attack host cells through viral proteins and surface receptors ...
Shahana Akhter Deena +4 more
wiley +1 more source