Results 61 to 70 of about 35,966 (245)

Preclinical Evaluation of a Bone-Marrow Autograft Culture Procedure for Generating Lymphokine-Activated Killer Cells in Vitro

open access: yesCanadian Journal of Infectious Diseases, 1992
Despite the use of high dose chemoradiotherapy for the treatment of acute leukemia. relapse continues to be a major cause of death in patients given an autologous bone marrow transplant.
Hans-Georg Klingemann   +3 more
doaj   +1 more source

Suppressive and immunoprotective functions of Tregs

open access: yesFrontiers in Immunology, 2011
CD4+CD25+Foxp3+ T lymphocytes, known as regulatory T cells or Tregs, have been proposed to be a lineage of professional immune suppressive cells that exclusively counteract the effects of the immunoprotective "helper" and "cytotoxic" ...
Pushpa ePandiyan   +2 more
doaj   +1 more source

Old Remedies in the Biotechnology Age: Moore v. Regents [PDF]

open access: yes, 1992
The California Supreme Court, by excluding a potential remedy, has eliminated many concerns generated by a lower court decision resolving rights to the cell line derived from John Moore\u27s spleen.
Burke, Michelle J., Schmidt, Victoria M.
core   +2 more sources

The Role of T‐Helper 17 Cells and Regulatory T Cells in Acute Diffuse and Total Alopecia: The Increased Function of Regulatory T Cells May Explain the Favorable Prognosis

open access: yesThe Journal of Dermatology, Volume 52, Issue 7, Page 1138-1145, July 2025.
ABSTRACT Background Acute diffuse and total alopecia (ADTA) is a variant of alopecia areata (AA) that lacks the typical patchy hair loss seen in classical AA and presents with an acute onset of diffuse hair loss. It has a favorable prognosis. Objectives The purpose of this study was to assess the role of T‐helper (Th) 17 cells and regulatory T cells ...
Ji‐Hoon Lim   +4 more
wiley   +1 more source

Role of periodontal pathogenic bacteria in RANKL-mediated bone destruction in periodontal disease

open access: yesJournal of Oral Microbiology, 2010
Accumulated lines of evidence suggest that hyperimmune responses to periodontal bacteria result in the destruction of periodontal connective tissue and alveolar bone.
Mikihito Kajiya   +5 more
doaj   +1 more source

Immunosuppressive and Non‐Immunosuppressive Drugs for Heart Xenotransplantation in Humans: Is Europe Ready?

open access: yesXenotransplantation, Volume 32, Issue 4, July/August 2025.
ABSTRACT Xenotransplantation is becoming an emerging field of interest for the treatment of end‐stage heart disease. In fact, the shortage of human heart donors in European countries requires the increasing investigation of alternative strategies such as heart xenotransplantation.
Nicola Pradegan   +6 more
wiley   +1 more source

CD8+, HLA-unrestricted, cytotoxic T-lymphocyte line against malignant melanoma

open access: yesJournal of Translational Medicine, 2005
A CD8+ cytotoxic T lymphocyte (CTL) line was derived from the peripheral blood mononuclear cells of a patient with primary melanoma. The CD8+ CTL line specifically lysed the autologous primary melanoma cells and not the natural killer cell-sensitive K562
Guerry DuPont   +3 more
doaj   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

open access: yes, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Azza Azza Abdel-Aziz   +5 more
core   +1 more source

2′‐Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
2′‐fucosyllactose prevented DSS‐induced intestinal inflammatory damage through exerting prebiotic capacity and regulating the intestinal immune response to gut microbiota. ABSTRACT Inflammatory bowel disease (IBD), a recurrent gastrointestinal disease, is characterized by dysbiosis and inflammation.
Jiamin Dong   +4 more
wiley   +1 more source

A preliminary study on IL4 levels in extrinsic atopic asthmatic children

open access: yesThe Turkish Journal of Pediatrics, 1994
Interleukin 4, (IL4) known as a lymphokine secreted by type II helper T-cells, is thought to regulate IgG and IgE secretions. Therefore, elevated IL4 levels are expected in atopic allergic disease and parasitoses.
N Akçakaya   +4 more
doaj  

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