Results 71 to 80 of about 35,966 (245)

Molecular and cellular basis of hepatic fibrogenesis in experimental schistosomiasis mansoni infection

Memorias do Instituto Oswaldo Cruz, 1992
Morbidity in schistosomiasis mansoni occurs primaryly as a result of the complications of hepatic fibrosis. Yet, the pathogenesis of schistosomal hepatic fibrosis is poorly understood. The fact that hepatic egg granuloma is the hallmark of this infection
David J. Wyler
doaj   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

Advanced Science, Volume 12, Issue 18, May 15, 2025.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang, Qingqing Feng, Chuanming Zheng, Yuanqiang Li, Xinyang Ge, Tiefeng Jin, Gaofeng Hu, Zhuo Tan, Jiafeng Wang, Jiajie Xu, Liehao Jiang, Dan Wang, Zhangguo Ying, Xiao Zhao, Keman Cheng, Qinglin Li, Minghua Ge   +16 more
wiley   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

Cell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou, Yifeng Chen, Yuhao Ba, Hui Xu, Anning Zuo, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Yuqing Ren, Peng Luo, Quan Cheng, Lulu Zuo, Shanshan Zhu, Xing Zhou, Chuhan Zhang, Yukang Chen, Xinwei Han, Teng Pan, Zaoqu Liu   +18 more
wiley   +1 more source

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. [PDF]

, 1989
We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice.
Coffman, RL, Heinzel, FP, Holaday, BJ, Locksley, RM, Sadick, MD   +4 more
core  

Biological processes and factors involved in soft and hard tissue healing

Periodontology 2000, Volume 97, Issue 1, Page 16-42, February 2025.
Abstract Wound healing is a complex and iterative process involving myriad cellular and biologic processes that are highly regulated to allow satisfactory repair and regeneration of damaged tissues. This review is intended to be an introductory chapter in a volume focusing on the use of platelet concentrates for tissue regeneration.
Mark Bartold, Saso Ivanovski
wiley   +1 more source

Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review.

PLoS ONE, 2012
PurposeThe effectiveness of immunotherapy for postoperative hepatocellular carcinoma patients is still controversial. To address this issue, we did a systemic review of the literatures and analyzed the data with emphasis on the recurrence and survival ...
Feng Xie, Xinji Zhang, Hui Li, Tao Zheng, Feng Xu, Rongxi Shen, Long Yan, Jiamei Yang, Jia He   +8 more
doaj   +1 more source

Parasite specific energy in human filariasis; insights after analysis of parasite antigen-driven lymphokine production [PDF]

, 1987
The antigen-specific immune unresponsiveness seen in bancroftian filariasis was studied by examining lymphokine production in peripheral blood mononuclear cells (PBMC) or PBMC subpopulations from 10 patients with asymptomatic microfilaremia, 13 ...
Kumaraswami, V, Nutman, T B, Ottesen, E A   +2 more
core  

Heterogeneity of autoreactive T cell clones specific for the E2 component of the pyruvate dehydrogenase complex in primary biliary cirrhosis. [PDF]

, 1995
The extraordinary specificity of bile duct destruction in primary biliary cirrhosis (PBC) and the presence of T cell infiltrates in the portal tracts have suggested that biliary epithelial cells are the targets of an autoimmune response.
Ansari, A, Coppel, R, Gershwin, M, Kotzin, B, Krams, S, Liu, S, Munoz, S, Prindiville, T, Ricalton, N, Roche, T, Van De Water, Judith   +10 more
core   +2 more sources

Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study

Health Science Reports, Volume 8, Issue 1, January 2025.
ABSTRACT Background and Aims Dengue is a mosquito‐borne viral disease that frequently causes seasonal outbreaks in Bangladesh, particularly during the monsoon months from June to September. Recent outbreaks have shown significant shifts in clinical manifestations, including changes in the timeframe and serotype mixing.
Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid   +4 more
wiley   +1 more source

NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. [PDF]

, 1995
NKR-P1A is a lectinlike surface molecule expressed on rat natural killer (NK) cells. NKR-P1A has structural and functional features of an activating NK cell receptor, but a requirement for NKR-P1A in target cell lysis has not been determined.
Nakamura, MC, Niemi, EC, Ryan, JC, Seaman, WE   +3 more
core