Results 81 to 90 of about 34,684 (258)

The low efficiency of dendritic cells and macrophages from mice susceptible to Paracoccidioides brasiliensis in inducing a Th1 response

open access: yesBrazilian Journal of Medical and Biological Research, 2001
In the present study we evaluated T cell proliferation and Th lymphokine patterns in response to gp43 from Paracoccidioides brasiliensis presented by isolated dendritic cells from susceptible and resistant mice.
S.R. Almeida, J.D. Lopes
doaj   +1 more source

Constitutive expression of high affinity interleukin 2 receptors on human CD16-natural killer cells in vivo. [PDF]

open access: yes, 1990
The majority of human NK cells express low affinity IgG Fc receptors (CD16+), whereas a minor subset of NK cells lack Fc receptor expression (CD16-). In contrast to CD16+ NK cells that express only p75 IL-2 receptors, CD16- NK cells constitutively co ...
Lanier, LL, Nagler, A, Phillips, JH
core  

Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles [PDF]

open access: yes, 1994
Elevation of cAMP can cause gene-specific inhibition of interleukin 2 (IL-2) expression. To investigate the mechanism of this effect, we have combined electrophoretic mobility shift assays and in vivo genomic footprinting to assess both the availability ...
Chen, Dan, Rothenberg, Ellen V.
core   +2 more sources

The effects of inhaled corticosteroids on healthy airways

open access: yesAllergy, Volume 79, Issue 7, Page 1831-1843, July 2024.
4‐week ICS suppressed a broad spectrum of genes associated with adaptive T and B cell, and innate immunity, likely explaining the association between ICS use and pneumonia. Tonic T2 signalling in healthy airways was exquisitively sensitive to ICS, while an IL‐17‐dependent gene signature and CEACAM family members were not upregulated by 4‐week ICS ...
Emanuele Marchi   +15 more
wiley   +1 more source

Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]

open access: yes, 2011
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Azza Azza Abdel-Aziz   +5 more
core   +1 more source

Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence. [PDF]

open access: yes, 2020
There is a growing body of literature demonstrating the importance of T cell exhaustion in regulating and shaping immune responses to pathogens and cancer.
Canter, Robert J   +2 more
core  

Research progress of adoptive cell therapy in malignant glioma

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2016
Malignant glioma is the most common malignant tumor of central nervous system (CNS). Surgery is the main treatment method, supplemented by radiation and chemotherapy.
Meng LI
doaj  

Profound Functional Suppression of Tumor-Infiltrating T-Cells in Ovarian Cancer Patients Can Be Reversed Using PD-1-Blocking Antibodies or DARPin® Proteins

open access: yesJournal of Immunology Research, 2020
PD-1/PD-L1 blockade has revolutionized the field of immunooncology. Despite the relative success, the response rate to anti-PD-1 therapy requires further improvements. Our aim was to explore the enhancement of T-cell function by using novel PD-1-blocking
Emelie Foord   +15 more
doaj   +1 more source

Old Remedies in the Biotechnology Age: Moore v. Regents [PDF]

open access: yes, 1992
The California Supreme Court, by excluding a potential remedy, has eliminated many concerns generated by a lower court decision resolving rights to the cell line derived from John Moore\u27s spleen.
Burke, Michelle J., Schmidt, Victoria M.
core   +2 more sources

Adenosine Deaminase Activities in Sera, Lymphocytes and Granulocytes in Patients with Cutaneous Leishmaniasis

open access: yesMemorias do Instituto Oswaldo Cruz, 1998
Adenosine deaminase (ADA) activities in sera, lymphocytes and granulocytes in patients with cutaneous leishmaniasis were investigated and compared with control groups. Fifty patients and 50 healthy individuals were studied.
Erel Ozcan   +5 more
doaj  

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