Results 81 to 90 of about 35,966 (245)
IET Systems Biology, Volume 19, Issue 1, January/December 2025.In this paper, we propose a robust control method for the automatic treatment of targeted anti‐angiogenic molecular therapy based on multi‐input multi‐output (MIMO) nonlinear fractional and non‐fractional models using the backstepping (BS) approach.
Mohamadreza Homayounzade +1 more
wiley +1 more source
"Tolerization" of human T-helper cell clones by chronic exposure to alloantigen [PDF]
, 1988 Induction of clonal anergy in T-helper (Th) cells may have a role in regulating immune responses. A model system for studying Th cell tolerization at the clonal level in vitro could be useful for investigating the mechanisms involved.
Brocker, Thomas +6 more
core
Immune activation by combination human lymphokine-activated killer and dendritic cell therapy. [PDF]
, 2011 BACKGROUND: Optimal cellular immunotherapy for cancer should ideally harness both the innate and adaptive arms of the immune response. Lymphokine-activated killer cells (LAKs) can trigger early innate killing of tumour targets, whereas long-term adaptive-
Jennings, VA +3 more
core +1 more source
Brazilian Journal of Medical and Biological Research, 2001 In the present study we evaluated T cell proliferation and Th lymphokine patterns in response to gp43 from Paracoccidioides brasiliensis presented by isolated dendritic cells from susceptible and resistant mice.
S.R. Almeida, J.D. Lopes
doaj +1 more source
Autologous lymphokine-activated killer cell therapy of lymphoproliferative disorders arising in organ transplant recipients [PDF]
, 1997 Cell lymphomas which often contain the Epstein-Barr virus (EBV) make up the preponderance of tumors that collectively have been termed posttransplant lymphoproliferative disorders (PTLD).
Alard +14 more
core +2 more sources
Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. [PDF]
, 1996 NKB1 is one member of a growing family of killer cell inhibitory receptors (KIR). It is expressed on natural killer (NK) cells and T cells, and has been shown to inhibit cytolytic functions of these cells upon interacting with its ligand, HLA-B (Bw4). We
Fry, AM, Lanier, LL, Weiss, A
core +1 more source
In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]
, 1987 We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Koszinowski, Ulrich H. +2 more
core +3 more sources
Research progress of adoptive cell therapy in malignant glioma
Chinese Journal of Contemporary Neurology and Neurosurgery, 2016 Malignant glioma is the most common malignant tumor of central nervous system (CNS). Surgery is the main treatment method, supplemented by radiation and chemotherapy.
Meng LI
doaj
Memorias do Instituto Oswaldo Cruz, 1998 Adenosine deaminase (ADA) activities in sera, lymphocytes and granulocytes in patients with cutaneous leishmaniasis were investigated and compared with control groups. Fifty patients and 50 healthy individuals were studied.
Erel Ozcan +5 more
doaj
Journal of Immunology Research, 2020 PD-1/PD-L1 blockade has revolutionized the field of immunooncology. Despite the relative success, the response rate to anti-PD-1 therapy requires further improvements. Our aim was to explore the enhancement of T-cell function by using novel PD-1-blocking
Emelie Foord +15 more
doaj +1 more source