Results 81 to 90 of about 34,684 (258)
In the present study we evaluated T cell proliferation and Th lymphokine patterns in response to gp43 from Paracoccidioides brasiliensis presented by isolated dendritic cells from susceptible and resistant mice.
S.R. Almeida, J.D. Lopes
doaj +1 more source
Constitutive expression of high affinity interleukin 2 receptors on human CD16-natural killer cells in vivo. [PDF]
The majority of human NK cells express low affinity IgG Fc receptors (CD16+), whereas a minor subset of NK cells lack Fc receptor expression (CD16-). In contrast to CD16+ NK cells that express only p75 IL-2 receptors, CD16- NK cells constitutively co ...
Lanier, LL, Nagler, A, Phillips, JH
core
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles [PDF]
Elevation of cAMP can cause gene-specific inhibition of interleukin 2 (IL-2) expression. To investigate the mechanism of this effect, we have combined electrophoretic mobility shift assays and in vivo genomic footprinting to assess both the availability ...
Chen, Dan, Rothenberg, Ellen V.
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The effects of inhaled corticosteroids on healthy airways
4‐week ICS suppressed a broad spectrum of genes associated with adaptive T and B cell, and innate immunity, likely explaining the association between ICS use and pneumonia. Tonic T2 signalling in healthy airways was exquisitively sensitive to ICS, while an IL‐17‐dependent gene signature and CEACAM family members were not upregulated by 4‐week ICS ...
Emanuele Marchi+15 more
wiley +1 more source
Distinct cytokine patterns in Occult Hepatitis C and Chronic Hepatitis C Virus Infection [PDF]
Background & Aim: The immunopathogenesis of chronic hepatitis C virus (HCV) infection is a matter of great controversy. The imbalance of T-helper lymphocyte cell cytokine production was believed to play an important pathogenic role in ...
Azza Azza Abdel-Aziz+5 more
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Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence. [PDF]
There is a growing body of literature demonstrating the importance of T cell exhaustion in regulating and shaping immune responses to pathogens and cancer.
Canter, Robert J+2 more
core
Research progress of adoptive cell therapy in malignant glioma
Malignant glioma is the most common malignant tumor of central nervous system (CNS). Surgery is the main treatment method, supplemented by radiation and chemotherapy.
Meng LI
doaj
PD-1/PD-L1 blockade has revolutionized the field of immunooncology. Despite the relative success, the response rate to anti-PD-1 therapy requires further improvements. Our aim was to explore the enhancement of T-cell function by using novel PD-1-blocking
Emelie Foord+15 more
doaj +1 more source
Old Remedies in the Biotechnology Age: Moore v. Regents [PDF]
The California Supreme Court, by excluding a potential remedy, has eliminated many concerns generated by a lower court decision resolving rights to the cell line derived from John Moore\u27s spleen.
Burke, Michelle J., Schmidt, Victoria M.
core +2 more sources
Adenosine deaminase (ADA) activities in sera, lymphocytes and granulocytes in patients with cutaneous leishmaniasis were investigated and compared with control groups. Fifty patients and 50 healthy individuals were studied.
Erel Ozcan+5 more
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