Results 11 to 20 of about 9,051 (165)

Characterization of the SARS-CoV-2-Specific T Cell Responses in Rheumatoid Arthritis Subjects Vaccinated for COVID-19 Protection. [PDF]

open access: yesEur J Immunol
SARS‐CoV‐2 vaccination in rheumatoid arthritis leads to the development of CD4+ and CD8+ spike‐specific T cell memory, regardless of immunosuppressive therapies, and the number of vaccine injections. CD4−CD8− double‐negative (DN) T cells responded to SARS‐CoV‐2 peptide epitopes and differentiated into CD8+ cytotoxic T cells after stimulation ...
Song J   +5 more
europepmc   +2 more sources

Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]

open access: yesMediators Inflamm
Autoimmune disorders encompass a varied range of diseases in which the immune system mistakenly targets and attacks the body’s own tissues. The causes of the conditions are unknown. It is presumed that various genetic, environmental, and immune factors all play a part.
Farahani H   +4 more
europepmc   +2 more sources

A Review: Can Cytokines Induce Vascular Inflammation as a Sequela of Viral Infections? [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background and Aim There are many unknown consequences of viral infections. In this piece, we looked at one of these effects that influence the venous system of the body, vasculitis, an inflammation of the blood vessels. Discussion The study illustrates that viral infections attack host cells through viral proteins and surface receptors ...
Deena SA   +4 more
europepmc   +2 more sources

Tocilizumab Dosing for Management of T Cell-Engaging Bispecific Antibody-Related CRS in Patients With R/R B-Cell NHL. [PDF]

open access: yesClin Pharmacol Ther
Tocilizumab dosing for management of T cell‐engaging bispecific antibody‐related CRS in patients with R/R B‐cell NHL. The recent surge in T‐cell‐engaging and chimeric antigen receptor (CAR) T‐cell therapies is changing the landscape of cancer therapy.
Jamois C   +13 more
europepmc   +2 more sources

Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle

open access: yesJournal of Veterinary Research, 2018
Introduction:Coxiella (C.) burnetii, the aetiological agent of Q fever, is able to modulate the macrophage/T-lymphocyte axis in an infected organism and impair synthesis of monokines and lymphokines.
Małaczewska Joanna   +6 more
doaj   +1 more source

Cytokines as determinants of disease and disease interactions

open access: yesBrazilian Journal of Medical and Biological Research, 1998
The immune response to pathogens results in both host resistance and immunopathology. Cytokines and in particular those lymphokines produced by Th1 and Th2 cells play a key role in determining the balance between these two immunologic outcomes.
A. Sher   +6 more
doaj   +1 more source

Epigenetic modulation of selected immune response genes and altered functions of T lymphocytes and macrophages collectively contribute to autoimmune diabetes protection

open access: yesBBA Advances, 2021
We have previously demonstrated that weekly treatment of female prediabetic NOD mice with a low dose of the histone deacetylase inhibitor Trichostatin A (TSA) bestowed long-lasting, irreversible protection against autoimmune diabetes. Herein we show that
Arathi Jayaraman   +2 more
doaj   +1 more source

Impact Of Dietary Measures In Autoimmune Diseases

open access: yesJournal of Bahria University Medical and Dental College, 2019
The immune system of an individual upon activation by antigens produces response to pathogenic microorganisms their products and to body self-antigens.
Nasim Karim
doaj   +1 more source

A rapid, reliable method of evaluating growth and viability of intraerythrocytic protozoan hemoparasites using fluorescence flow cytometry

open access: yesMemorias do Instituto Oswaldo Cruz, 1992
Fluorescence flow cytometry was employed to assess the potential of a vital dye, hydroethiedine, for use in the detection and monitoring of the viability of hemoparasites in infected erythrocytes, using Babesia bovis as a model parasite.
W. C. Davis   +3 more
doaj   +1 more source

Interleukin-2 in Renal Cell Carcinoma: A Has-Been or a Still-Viable Option?

open access: yesJournal of Kidney Cancer and VHL, 2014
Modulation of the immune response plays an important role in the natural history of renal cell carcinoma.  Spontaneous regression of metastases has been well documented in a small percentage of patients after they undergo de-bulking nephrectomy without ...
Asim Amin, Richard L White
doaj   +1 more source

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