Results 11 to 20 of about 17,343 (207)

Characterization of the SARS-CoV-2-Specific T Cell Responses in Rheumatoid Arthritis Subjects Vaccinated for COVID-19 Protection. [PDF]

Eur J Immunol
SARS‐CoV‐2 vaccination in rheumatoid arthritis leads to the development of CD4+ and CD8+ spike‐specific T cell memory, regardless of immunosuppressive therapies, and the number of vaccine injections. CD4−CD8− double‐negative (DN) T cells responded to SARS‐CoV‐2 peptide epitopes and differentiated into CD8+ cytotoxic T cells after stimulation ...
Song J, da Silva Antunes R, Seyede MA, Guma M, Sette A, Franco A.   +5 more
europepmc   +2 more sources

Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]

Mediators Inflamm
Autoimmune disorders encompass a varied range of diseases in which the immune system mistakenly targets and attacks the body’s own tissues. The causes of the conditions are unknown. It is presumed that various genetic, environmental, and immune factors all play a part.
Farahani H, Kokhaei P, Ganji A, Mosayebi G, Ghazavi A.   +4 more
europepmc   +2 more sources

A Review: Can Cytokines Induce Vascular Inflammation as a Sequela of Viral Infections? [PDF]

Health Sci Rep
ABSTRACT Background and Aim There are many unknown consequences of viral infections. In this piece, we looked at one of these effects that influence the venous system of the body, vasculitis, an inflammation of the blood vessels. Discussion The study illustrates that viral infections attack host cells through viral proteins and surface receptors ...
Deena SA, Tonima SA, Khan SA, Biswas MS, Dewan SMR.   +4 more
europepmc   +2 more sources

Tocilizumab Dosing for Management of T Cell-Engaging Bispecific Antibody-Related CRS in Patients With R/R B-Cell NHL. [PDF]

Clin Pharmacol Ther
Tocilizumab dosing for management of T cell‐engaging bispecific antibody‐related CRS in patients with R/R B‐cell NHL. The recent surge in T‐cell‐engaging and chimeric antigen receptor (CAR) T‐cell therapies is changing the landscape of cancer therapy.
Jamois C, Turner DC, Gibiansky L, Li F, Menuet JF, Pereira LR, Lundberg L, Guerini E, Carlile DJ, Relf J, Wei MC, Kwan A, Frey N, Grange S.   +13 more
europepmc   +2 more sources

New simplified molecular design for functional T cell receptor [PDF]

, 1993
We have produced a chimeric single-chain T cell receptor (TcR) that combines the specific antibody recognition function and TcR/CD3 signaling properties within the same polypeptide chain.
Clevers, Cosson, Eshhar, Frank, Gillis, Gunning, Hackett, Huston, Ihle, Irving, Lanzavecchia, Leo, Mosmann, Oi, Romeo, Sterz, Tada, Traunecker, Walker, Wegener, Weissman, Weissman, White, Zamoyska   +23 more
core   +1 more source

Identification and antiviral effect of Cherry Valley duck IRF4

Poultry Science, 2022
: Interferon regulatory factor 4 (IRF4) is a multifunctional transcription factor that plays an important regulatory role in the interferon (IFN) signaling.
Xinyu Zhai, Tianqi Hong, Tingting Zhang, Bin Xing, Jinchao Wang, Xiuyuan Wang, Runchun Miao, Tianxu Li, Liangmeng Wei   +8 more
doaj   +1 more source

Lymphokines.

Allergologia et immunopathologia, 1983
Lymphokines are defined as nonimmunoglobulin secretory products of activated lymphocytes with a wide range of potent physiological effects on inflammation and immune responses. In this review, we summarized the recent development in lymphokine researches, including biochemical and immunological approaches.
K, Okuno, T, Hamaoka
  +7 more sources

Effects of cytokines on the production of lipoprotein lipase in cultured human macrophages.

Journal of Lipid Research, 1990
Macrophages are important cells in the pathogenesis of atherosclerosis because of their tendency to accumulate lipid and become transformed into foam cells.
U Querfeld, JM Ong, J Prehn, J Carty, B Saffari, SC Jordan, PA Kern   +6 more
doaj   +1 more source

[Lymphokines].

Kekkaku : [Tuberculosis], 1976
Peritoneal exudate macrophages in guinea pigs and peripheral blood monocytes in man are the most readily available cells sensitive to the migration-inhibiting factor(s) (MIF) induced by tuberculin or insoluble concanavalin A in supernatants of stimulated lymphocyte cultures.
Wilhelm Friedrich, Sandor Lazary, Alain L. de Weck   +2 more
  +5 more sources

Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle

Journal of Veterinary Research, 2018
Introduction:Coxiella (C.) burnetii, the aetiological agent of Q fever, is able to modulate the macrophage/T-lymphocyte axis in an infected organism and impair synthesis of monokines and lymphokines.
Małaczewska Joanna, Kaczorek-Łukowska Edyta, Szymańska-Czerwińska Monika, Rękawek Wojciech, Wójcik Roman, Niemczuk Krzysztof, Siwicki Andrzej Krzysztof   +6 more
doaj   +1 more source