Results 41 to 50 of about 17,343 (207)
Old Remedies in the Biotechnology Age: Moore v. Regents [PDF]
The California Supreme Court, by excluding a potential remedy, has eliminated many concerns generated by a lower court decision resolving rights to the cell line derived from John Moore\u27s spleen.
Burke, Michelle J., Schmidt, Victoria M.
core +2 more sources
Processing and release of endogenous immunogenic peptide signals
SUMMARY In both animals and plants, small secreted peptides known as cytokines and phytocytokines mediate local and systemic communication during immune and stress responses. These signaling molecules are typically synthesized as inactive precursors that require proteolytic processing to become active.
Maurice Koenig +3 more
wiley +1 more source
Regulatory Networks Contributing to Psoriasis Susceptibility [PDF]
The non-involved, healthy-looking skin of psoriatic pa- tients displays inherent characteristics that make it pro- ne to develop typical psoriatic symptoms.
Bata-Csorgo, Zsuzsanna +7 more
core +1 more source
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie +3 more
wiley +1 more source
Immunotherapy of COVID-19: Inside and Beyond IL-6 Signalling
Acting on the cytokine cascade is key to preventing disease progression and death in hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 inhibitors have been the most used and studied since the beginning of the pandemic.
Gaetano Zizzo +7 more
doaj +1 more source
Modern biotherapy has been in use for some 30 years. The first types of biotherapy were nonspecific stimulators of the immune response, but advances in genetic engineering are allowing the mass production of pure biological products which are now being ...
Gallucci, Betty Bierut +1 more
core +1 more source
Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy
ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng +8 more
wiley +1 more source
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody-dependent, cell-mediated cytotoxicity or ...
Robert O Dillman
doaj +1 more source
CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. [PDF]
Activation of an immune response requires intercellular contact between T lymphocytes and antigen-presenting cells (APC). Interaction of the T cell antigen receptor (TCR) with antigen in the context of major histocompatibility molecules mediates signal ...
Fraser, JD, Newton, ME, Weiss, A
core
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen +16 more
wiley +1 more source

