Results 41 to 50 of about 9,051 (165)

The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts

open access: yesFrontiers in Immunology, 2018
The immune suppressants cyclosporin A (CsA) and tacrolimus (FK506) are used worldwide in transplantation medicine to suppress graft rejection. Both CsA and FK506 inhibit the phosphatase calcineurin (CN) whose activity controls the immune receptor ...
Johannes Baur   +12 more
doaj   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen   +16 more
wiley   +1 more source

Thioglycollate-elicited murine macrophages are cytotoxic to Mycoplasma arginini-infected YAC-1 tumor cells

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Macrophages are important components of natural immunity involved in inhibition of tumor growth and destruction of tumor cells. It is known that these cells can be activated for tumoricidal activity by lymphokines and bacterial products.
F. Ribeiro-Dias   +5 more
doaj   +1 more source

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang   +4 more
wiley   +1 more source

ИММУНОТОКСИЧЕСКИЕ СВОЙСТВА ПРЕПАРАТА ЦИПРОВЕТ 10% ОРАЛЬНОГО

open access: yesВетеринарная патология, 2010
Ciprovet 10% causes a decrease in oral RGZT, which indicates the ability to stimulate production of lymphokines and enhances the activity of helper cells.

doaj  

Research progress of active polypeptides of Cordyceps militaris

open access: yesBIO Web of Conferences, 2017
It is recognized at home and abroad that Cordyceps militaris is a fungus that can be edible and used for medicinal application, and also a common cordyceps taishanensis that is widely distributed and with very high medicinal value in China.
Xu Guangyu   +5 more
doaj   +1 more source

Excited Skin Syndrome (Angry Back), What Do We Know About It? A Review of the Literature

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background In 1975, Mitchell brought up a theory that false positive reactions can be due to skin hyperirritability, called it “angry back syndrome” (ABS). The phenomenon is observed in patch testing of patients with several positive patch tests, mostly along with one or more strong reactions.
Amir Mohammad Beyzaee, Howard I. Maibach
wiley   +1 more source

A narrative review on the role of magnesium in immune regulation, inflammation, infectious diseases, and cancer

open access: yesJournal of Health, Population and Nutrition, 2023
Background Magnesium (Mg) has gained much importance recently because of its unique range of biological functions. It is one of the most significant micronutrients in biological systems. This review aims to outline the immune-regulating actions of Mg and
Sumel Ashique   +9 more
doaj   +1 more source

Influence of dental filling material type on the concentration of interleukin 9 in the samples of gingival crevicular fluid [PDF]

open access: yesVojnosanitetski Pregled, 2016
Background/Aim. Several cytokines and lymphokines (IL1β, ENA78, IL6, TNFα, IL8 and S100A8) are expressed during dental pulp inflammation. Analysis of gingival crevicu-lar fluid (GCF) offers a non-invasive means of studying gen-eral host response in oral ...
Stefanović Vladimir   +10 more
doaj   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

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