Results 51 to 60 of about 10,206 (200)
Endotoxin requirement for macrophage activation by lymphokines in a rapid microcytotoxicity assay [PDF]
, 1980 A short term microcytotoxicity assay is described for studying the activation of M0 by lymphokines. Proteose-peptone-induced macrophages were purified by adherence in flat-bottomed microtiter plates and then activated by MAF-containing supernatants for ...
D. Taramelli, H. T. Holden, L. Varesio
core +1 more source
Immunotherapy of COVID-19: Inside and Beyond IL-6 Signalling
Frontiers in Immunology, 2022 Acting on the cytokine cascade is key to preventing disease progression and death in hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 inhibitors have been the most used and studied since the beginning of the pandemic.
Gaetano Zizzo +7 more
doaj +1 more source
Reconceptualizing Aplastic Anemia—Seed, Worm, Soil
Journal of Clinical Laboratory Analysis, Volume 40, Issue 14, July 2026.Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu +4 more
wiley +1 more source
Priming of peripheral lymph node B cells with TNP-Ficoll: Role of lymphokines in B cell differentiation [PDF]
, 1992 We have previously shown that peripheral lymph node (PLN) B lymphocytes of adult DBA/ 25 mice failed to make an antibody responseto type 2 antigen TNP-Ficoll, but exhibited a good antibody response to type 1 antigen TNP-BruceNa abortus.
S.Niranjan Goud +5 more
core +1 more source
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Canadian Journal of Infectious Diseases, 1992 Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody-dependent, cell-mediated cytotoxicity or ...
Robert O Dillman
doaj +1 more source
Evidence for PDZ‐Binding Kinase in Lung Disease With an Emphasis on PAH
Pulmonary Circulation, Volume 16, Issue 3, July 2026.ABSTRACT Originally named T‐cell‐originated Lymphokine‐activated killer protein kinase (TOPK), PDZ‐Binding Kinase (PBK) is a serine/threonine kinase that is a member of the family of mitogen‐activated protein kinases (MAPKKs), which is overexpressed in lung cancer and interstitial pulmonary fibrosis (IPF). Along these lines, recent work also shows that
Scott A. Barman +2 more
wiley +1 more source
MECHANISMS OF VIRUS-INDUCED IMMUNOSUPPRESSION AND MODULATION OF VIRUS MULTIPLICATION BY LYMPHOKINES. [PDF]
, 1985 MECHANISMS OF VIRUS-INDUCED IMMUNOSUPPRESSION AND MODULATION OF VIRUS MULTIPLICATION BY ...
NIWAT. MANEEKARN (7981184)
core
UM4D4+ (CDw60) T Cells Are Compartmentalized into Psoriatic Skin and Release Lymphokines That Induce a Keratinocyte Phenotype Expressed in Psoriatic Lesions [PDF]
, 1990 UM4D4 (CDw60), the surface molecule of a novel antigen- independent T-cell activation pathway, was found to be highly expressed on lesional psoriatic T cells. To examine whether UM4D4 represents a T-cell activation pathway for psoriatic T cells, a T-cell
Hammerberg, Craig +11 more
core +1 more source
The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts
Frontiers in Immunology, 2018 The immune suppressants cyclosporin A (CsA) and tacrolimus (FK506) are used worldwide in transplantation medicine to suppress graft rejection. Both CsA and FK506 inhibit the phosphatase calcineurin (CN) whose activity controls the immune receptor ...
Johannes Baur +12 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil +6 more
wiley +1 more source