Results 11 to 20 of about 2,347,326 (232)

Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]

, 2015
Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan, Gilmore, Thomas D., Porco, John A., Whitty, Adrian, Yeo, Alan T.   +4 more
core   +2 more sources

Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell–Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial

Journal of Clinical Oncology, 2022
PURPOSE Epcoritamab is a subcutaneously administered CD3xCD20 T-cell–engaging, bispecific antibody that activates T cells, directing them to kill malignant CD20+ B cells.
C. Thieblemont, T. Phillips, H. Ghesquières, C. Cheah, M. Clausen, D. Cunningham, Y. Do, T. Feldman, R. Gasiorowski, W. Jurczak, Tae Min Kim, D. Lewis, M. van der Poel, M. Poon, Mariana Cota Stirner, N. Kilavuz, Christopher W Chiu, Meng‐Yu Chen, M. Sacchi, B. Elliott, T. Ahmadi, M. Hutchings, P. Lugtenburg   +22 more
semanticscholar   +1 more source

Preliminary evidence of imaging of chemokine receptor-4-targeted PET/CT with [68Ga]pentixafor in non-Hodgkin lymphoma: comparison to [18F]FDG

EJNMMI Research, 2020
Background In order to study the CXCR4 expression with [68Ga]pentixafor PET in different types of non-Hodgkin lymphoma, we performed a retrospective study to describe the [68Ga]pentixafor PET/CT imaging in a spectrum of lymphomas and to compare it with ...
Qingqing Pan, Yaping Luo, Yan Zhang, Long Chang, Ji Li, Xinxin Cao, Jian Li, Fang Li   +7 more
doaj   +1 more source

Primary cutaneous B‐cell lymphomas [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2011
SummaryCutaneous B‐cell lymphomas (CBCL) are the second most common form of primary cutaneous lymphomas. The cutaneous follicle center lymphoma and the cutaneous marginal zone lymphoma (extranodal MALT type lymphoma) account for the vast majority of CBCL and manifest with nodules.
Kempf, Werner, Denisjuk, Natalja, Kerl, Katrin, Cozzio, Antonio, Sander, Christian   +4 more
openaire   +3 more sources

Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma.

New England Journal of Medicine, 2023
BACKGROUND In an analysis of the primary outcome of this phase 3 trial, patients with early relapsed or refractory large B-cell lymphoma who received axicabtagene ciloleucel (axi-cel), an autologous anti-CD19 chimeric antigen receptor T-cell therapy, as ...
J. Westin, O. Oluwole, M. Kersten, D. Miklos, M. Perales, A. Ghobadi, A. Rapoport, A. Sureda, C. Jacobson, U. Farooq, T. van Meerten, M. Ulrickson, M. Elsawy, L. Leslie, S. Chaganti, M. Dickinson, K. Dorritie, P. Reagan, J. Mcguirk, K. Song, P. Riedell, M. Minnema, Yin Yang, S. Vardhanabhuti, S. Filosto, P. Cheng, Shilpa A. Shahani, M. Schupp, C. To, F. Locke   +29 more
semanticscholar   +1 more source

BCL-W has a fundamental role in B cell survival and lymphomagenesis. [PDF]

, 2017
Compromised apoptotic signaling is a prerequisite for tumorigenesis. The design of effective therapies for cancer treatment depends on a comprehensive understanding of the mechanisms that govern cell survival.
Annette S. Kim, Barrett, Christine M. Eischen, Clare M. Adams, Gibson, Haldar, Jerald Z. Gong, John K. Choi, Lee, Placzek, Ramkrishna Mitra, Schmitz, Visco, Wang, Yang   +14 more
core   +2 more sources

Methylation profiling of mediastinal gray zone lymphoma reveals a distinctive signature with elements shared by classical Hodgkin’s lymphoma and primary mediastinal large B-cell lymphoma

Haematologica, 2011
Background Mediastinal gray zone lymphoma is a newly recognized entity with transitional morphological and immunophenotypic features between the nodular sclerosis subtype of Hodgkin’s lymphoma and primary mediastinal large B-cell lymphoma.
Franziska C. Eberle, Jaime Rodriguez-Canales, Lai Wei, Jeffrey C. Hanson, J. Keith Killian, Hong-Wei Sun, Lisa G. Adams, Stephen M. Hewitt, Wyndham H. Wilson, Stefania Pittaluga, Paul S. Meltzer, Louis M. Staudt, Michael R. Emmert-Buck, Elaine S. Jaffe   +13 more
doaj   +1 more source

A Phase I/II first-line study of R-CHOP plus B-cell receptor/NF-κB-double-targeting to molecularly assess therapy response [PDF]

, 2019
The ImbruVeRCHOP trial is an investigator-initiated, multicenter, single-arm, open label Phase I/II study for patients 61-80 years of age with newly diagnosed CD20+ diffuse large B-cell lymphoma and a higher risk profile (International Prognostic Index ...
Anagnostopoulos, Ioannis, Bittner, Aitomi, Denker, Sophy, Frick, Mareike, Hummel, Michael, Kase, Julia, Na, Il-Kang, Schmitt, Clemens A.   +7 more
core   +2 more sources

Intramural great vessel lymphoma presenting as thrombus in an aortic aneurysm

Human Pathology: Case Reports, 2019
Intravascular large B-cell lymphoma (IVLBCL) is a subtype of extranodal B-cell lymphoma with growth limited to the lumina of small vessels. Intramural great vessel lymphoma (IMGVL), on the contrary, is extremely rare and there have been only two reported
Sameera Rashid, Shehab F. Mohamed, Mohamed Yassin, Laith F. Tbishat, Hassan Al-Thani, Issam Albozom   +5 more
doaj   +1 more source

Intravascular large B‐cell lymphoma in renal cell carcinoma incidentally detected by robot‐assisted partial nephrectomy

IJU Case Reports, 2022
Introduction Intravascular large B‐cell lymphoma is a rare and aggressive type of extranodal large B‐cell lymphoma. Although intravascular large B‐cell lymphoma can invade various organs, renal involvement has been rarely reported. Synchronous occurrence
Michio Noda, Yutaka Enomoto, Yukari Shirasugi, Sumiyo Ando, Yukimasa Matsuzawa, Haruki Kume   +5 more
doaj   +1 more source