Results 71 to 80 of about 1,264,620 (412)

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Is Circulating DNA and Tumor Cells in Myeloma the Way Forward?

Hemato, 2022
Multiple myeloma (MM) is the second deadliest hematological cancer. Despite the enormous innovation on MM treatment in the last decades, still 48% of patients die within 5 years after diagnosis. MM diagnosis and therapeutic strategy mainly rely on direct
Emilie Arnault Carneiro, Filipa Barahona, Carolina Pestana, Cristina João   +3 more
doaj   +1 more source

Network strategies to study Epstein-Barr virus associated carcinomas and potential etiological mechanisms for oncogenesis [PDF]

arXiv, 2022
Diseased conditions are a consequence of some abnormality that are associated with clinical conditions in numerous cells and tissues affecting various organs. The common role of EBV (Epstein-Barr virus) in causing infectious mononucleosis (IM) affecting B-cells and epithelial cells and the development of EBV-associated cancers has been an area of ...
arxiv  

Composite lymphoma of concurrent T zone lymphoma and large cell B cell lymphoma in a dog. [PDF]

, 2019
BackgroundEvolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma.
Bienzle, Dorothee, Darzentas, Nikos, Deravi, Nariman, Hwang, Mei-Hua, Keller, Stefan M, Matsuyama, Arata, Richardson, Danielle   +6 more
core   +1 more source

An unusual initial presentation of mantle cell lymphoma arising from the lymphoid stroma of warthin tumor. [PDF]

, 2015
BackgroundWarthin tumors presenting concomitantly with a lymphoma is vanishingly rare with only 15 reported cases in English literature. Herein, we report an unusual initial presentation of a mantle cell lymphoma involving the lymphoid stroma of a ...
Arcega, Ramir S, Bhuta, Sunita, Blackwell, Keith E, Feinstein, Aaron J, Pullarkat, Sheeja T, Rao, Nagesh P   +5 more
core   +1 more source

Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group.

Journal of Clinical Oncology, 2014
PURPOSE Recent advances in imaging, use of prognostic indices, and molecular profiling techniques have the potential to improve disease characterization and outcomes in lymphoma.
Sally F. Barrington, N. Mikhaeel, L. Kostakoglu, M. Meignan, M. Hutchings, Stefan Müeller, Lawrence H. Schwartz, E. Zucca, Richard I. Fisher, J. Trotman, Otto S. Hoekstra, Rodney J. Hicks, Michael J. O'Doherty, R. Hustinx, A. Biggi, B. Cheson   +15 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Emperipolesis in a Case of Adult T Cell Lymphoblastic Lymphoma (Mediastinal type)-Detected at FNAC and Imprint Cytology [PDF]

, 2011
Emperipolesis is a condition in which viable hematopoetic cells are seen intact in the cytoplasm of host cell without damage. This phenomenon is seen in many physiologic and pathologic conditions, its presence in Rosai Dorfman disease (RDD) is ...
Abhishekh, MG, Amita, K, Geethalakshmi, U, Vijay Shankar, S   +3 more
core  

The NF-κB subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma

, 2016
The REL gene, encoding the NF-κB subunit c-Rel, is frequently amplified in B-cell lymphoma and functions as a tumour-promoting transcription factor. Here we report the surprising result that c-rel–/– mice display significantly earlier lymphomagenesis in ...
Bacon, C.M., Butterworth, J.A., Campbell, K.J., Cockell, S.J., Gewurz, B.E., Hunter, J.E., Perkins, N.D., Sellier, H., Thomas, H.D., Zhao, B.   +9 more
core   +1 more source

Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin's lymphoma.

New England Journal of Medicine, 1995
BACKGROUND High-dose chemotherapy followed by autologous bone marrow transplantation is a therapeutic option for patients with chemotherapy-sensitive non-Hodgkin's lymphoma who have relapses.
T. Philip, C. Guglielmi, A. Hagenbeek, Renier Somers, H. van der Lelie, D. Bron, P. Sonneveld, C. Gisselbrecht, J. Cahn, J. Harousseau, B. Coiffier, P. Biron, F. Mandelli, F. Chauvin   +13 more
semanticscholar   +1 more source