Results 51 to 60 of about 67,043 (290)

Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4+ T Cells in Chronic Lymphopenic Mice

Frontiers in Immunology, 2019
In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to lymphopenia.
Laura Knop, Charlotte Frommer, Diana Stoycheva, Katrin Deiser, Ulrich Kalinke, Thomas Blankenstein, Thomas Blankenstein, Thomas Blankenstein, Thomas Kammertoens, Ildiko Rita Dunay, Thomas Schüler   +10 more
doaj   +1 more source

Conceptual framework for SARS-CoV-2-related lymphopenia

, 2022
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Azizi, Y., Kouhpayeh, S., Khanahmad, H., Rahimmanesh, I.   +3 more
core   +1 more source

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical site infection (SSI) is a major complication after ileal pouch–anal anastomosis (IPAA) in pediatric ulcerative colitis (UC), significantly impairing quality of life. The lymphocyte‐to–C‐reactive protein ratio (LCR), a composite marker of systemic inflammation and immune/nutritional status, has emerged as a potential ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source

Lymphopenia in treatment-naive relapsing multiple sclerosis

, 2016
Lymphopenia accompanies some autoimmune diseases. A number of studies, but not others, have suggested that lymphopenia occurs in treatment-naive multiple sclerosis (MS), so the issue remains unresolved. This is important since lymphopenia may identify an
Galea, Ian, Lim, Zhi Wei, Elwood, Elliot, Naveed, Hammad   +3 more
core   +1 more source

A Systematic Review of Radiation-Related Lymphopenia in Genito-urinary Malignancies

, 2021
The impact of radiation-related lymphopenia on clinical outcomes has been reported in various solid malignancies such as high grade gliomas, head and neck cancers, thoracic malignancies and gastro-intestinal malignancies but its impact is not clearly ...
Hagar Elghazawy (11284736), Amrish Sharma (773710), Bhaswanth Dhanireddy (11284739), Ambedkar Yedala (11284727), Carlton Johnny (11284748), BK Kim (11284733), Cheng En Hsieh (11284745), Kannan Periasamy (11284721), BhanuPrasad Venkatesulu (11284751), Prashanth Giridhar (8916869), Rituraj Upadhya (11284730), Ishwariya Rajendran (11284724), Thiraviyam Elumalai (11284718), Supriya Mallick (11284742)   +13 more
core   +1 more source

Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: A longitudinal, multinational study [PDF]

, 2021
OBJECTIVE: The prevalence and associations of leucopenia in SLE remain incompletely understood. We evaluated associations of disease activity and medication use with leucopenia (lymphopenia and neutropenia) in a multinational, prospectively followed SLE ...
Lau, CS, Hoi, A, Chen, YH, Zamora, L, Wu, YJJ, Louthrenoo, W, Takeuchi, T, Hao, Y, Morand, E, Lateef, A, Goldblatt, F, Cho, J, Navarra, S, Nikpour, M, Katsumata, Y, Luo, SF, Kikuchi, J, Chan, M, Sockalingam, S, Kandane-Rathnayake, R, Harigai, M, Zhang, Z, Golder, V, Li, Z, Hamijoyo, L, O'neill, S, An, Y   +26 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Lymphopenia during opportunistic infections.

, 2016
Lymphopenia during opportunistic infections.
Marius Vögelin (2805241), Michael Fried (139963), Jonas Zeitz (389786), Pascal Frei (139961), Michael Scharl (139957), Gerhard Rogler (139954), Sylvie Scharl (2805235), Stephan R. Vavricka (139972), Michael C. Sulz (2805238), Luc Biedermann (139959)   +9 more
core   +1 more source

Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Animal Models and Experimental Medicine, EarlyView.
Pristane (5 mL/kg) induced a robust systemic lupus erythematosus (SLE)‐like phenotype in Macaca fascicularis, marked by elevated antinuclear antibody (ANA) levels and systemic clinical, hematological, and biochemical changes. This model closely reflects human SLE and provides a translational platform for disease studies and therapeutic evaluation ...
Jonny Jonny, Soetojo Wirjopranoto, Chairul A. Nidom, I Ketut Sudiana, Terawan A. Putranto, Elisa D. Pratiwi, Tiza W. Mawaddah, Astria N. Nidom, Reviany V. Nidom, Setyarina Indrasari, Irma Y. Rosytania, Hiqmah Y. Yana, Sanindita Kusumastuti   +12 more
wiley   +1 more source

Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey

Journal of Epidemiology, 2022
Background: Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external ...
Akira Sakai, Masanori Nagao, Hironori Nakano, Tetsuya Ohira, Tetsuo Ishikawa, Mitsuaki Hosoya, Michio Shimabukuro, Atsushi Takahashi, Junichiro J. Kazama, Kanako Okazaki, Fumikazu Hayashi, Seiji Yasumura, Hitoshi Ohto, Kenji Kamiya   +13 more
doaj   +1 more source