Results 51 to 60 of about 71,077 (191)

Conceptual framework for SARS-CoV-2-related lymphopenia

, 2022
The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Azizi, Y., Kouhpayeh, S., Khanahmad, H., Rahimmanesh, I.   +3 more
core   +1 more source

Interferon-γ Receptor Signaling in Dendritic Cells Restrains Spontaneous Proliferation of CD4+ T Cells in Chronic Lymphopenic Mice

Frontiers in Immunology, 2019
In lymphopenic mice, T cells become activated and undergo lymphopenia-induced proliferation (LIP). However, not all T cells are equally sensitive to lymphopenia.
Laura Knop, Charlotte Frommer, Diana Stoycheva, Katrin Deiser, Ulrich Kalinke, Thomas Blankenstein, Thomas Blankenstein, Thomas Blankenstein, Thomas Kammertoens, Ildiko Rita Dunay, Thomas Schüler   +10 more
doaj   +1 more source

Lymphopenia in treatment-naive relapsing multiple sclerosis

, 2016
Lymphopenia accompanies some autoimmune diseases. A number of studies, but not others, have suggested that lymphopenia occurs in treatment-naive multiple sclerosis (MS), so the issue remains unresolved. This is important since lymphopenia may identify an
Galea, Ian, Lim, Zhi Wei, Elwood, Elliot, Naveed, Hammad   +3 more
core   +1 more source

A Systematic Review of Radiation-Related Lymphopenia in Genito-urinary Malignancies

, 2021
The impact of radiation-related lymphopenia on clinical outcomes has been reported in various solid malignancies such as high grade gliomas, head and neck cancers, thoracic malignancies and gastro-intestinal malignancies but its impact is not clearly ...
Hagar Elghazawy (11284736), Amrish Sharma (773710), Bhaswanth Dhanireddy (11284739), Ambedkar Yedala (11284727), Carlton Johnny (11284748), BK Kim (11284733), Cheng En Hsieh (11284745), Kannan Periasamy (11284721), BhanuPrasad Venkatesulu (11284751), Prashanth Giridhar (8916869), Rituraj Upadhya (11284730), Ishwariya Rajendran (11284724), Thiraviyam Elumalai (11284718), Supriya Mallick (11284742)   +13 more
core   +1 more source

Lymphopenia in sepsis—an acquired immunodeficiency?

Immunology & Cell Biology, 2022
AbstractSepsis is a global health priority, yet effective host‐directed targeted therapies have not been identified outside of the setting of coronavirus disease 2019 (COVID‐19). Lymphopenia occurs in up to ~52% of patients with sepsis and is associated with a higher mortality at both 30 and 100 days. In COVID‐19, the presence of lymphopenia correlates
Simon, Finfer, Balasubramanian, Venkatesh, Richard S, Hotchkiss, Sarah C, Sasson   +3 more
openaire   +2 more sources

Lymphopenia during opportunistic infections.

, 2016
Lymphopenia during opportunistic infections.
Marius Vögelin (2805241), Michael Fried (139963), Jonas Zeitz (389786), Pascal Frei (139961), Michael Scharl (139957), Gerhard Rogler (139954), Sylvie Scharl (2805235), Stephan R. Vavricka (139972), Michael C. Sulz (2805238), Luc Biedermann (139959)   +9 more
core   +1 more source

Risk factors for development of lymphopenia in dimethyl fumarate-treated patients with multiple sclerosis [PDF]

, 2022
Background: Dimethyl fumarate (DMF, Tecfidera®) is a first-line disease-modifying therapy for relapsing-remitting multiple sclerosis. Lymphopenia is a frequent reason for discontinuation in fumarate-treated patients.
Góra, Monika Katarzyna, Jensen, Henrik Boye, Kant, Matthias, Sejbaek, Tobias; id_orcid, Ravn, Julie, Andersen, Preben Borring, Julie Ravn, Matthias Kant, Preben Borring Andersen, Monika Katarzyna Góra, Henrik Boye Jensen, Tobias Sejbaek   +11 more
core   +1 more source

Effects of External Radiation Exposure Resulting >From the Fukushima Daiichi Nuclear Power Plant Accident on the Health of Residents in the Evacuation Zones: the Fukushima Health Management Survey

Journal of Epidemiology, 2022
Background: Associations have been reported between lifestyle-related diseases and evacuation after the Great East Japan Earthquake (GEJE). However, the relationship between lifestyle-related diseases and the effective radiation dose due to external ...
Akira Sakai, Masanori Nagao, Hironori Nakano, Tetsuya Ohira, Tetsuo Ishikawa, Mitsuaki Hosoya, Michio Shimabukuro, Atsushi Takahashi, Junichiro J. Kazama, Kanako Okazaki, Fumikazu Hayashi, Seiji Yasumura, Hitoshi Ohto, Kenji Kamiya   +13 more
doaj   +1 more source

Regulatory T cell ablation causes acute T cell lymphopenia. [PDF]

, 2014
Regulatory T (Treg) cells enforce T cell homeostasis and maintain peripheral T cell tolerance. Here we report a previously unappreciated phenomenon of acute T cell lymphopenia in secondary lymphoid organs and non-lymphoid tissues triggered by Treg cell ...
Saskia Hemmers (214438), Saskia Hemmers, Bruno Moltedo, Alexander Y Rudensky, Bruno Moltedo (198061), Alexander Y. Rudensky (367443)   +5 more
core   +1 more source

Independent associations of lymphopenia and neutropenia in patients with systemic lupus erythematosus: A longitudinal, multinational study [PDF]

, 2021
OBJECTIVE: The prevalence and associations of leucopenia in SLE remain incompletely understood. We evaluated associations of disease activity and medication use with leucopenia (lymphopenia and neutropenia) in a multinational, prospectively followed SLE ...
Lau, CS, Hoi, A, Chen, YH, Zamora, L, Wu, YJJ, Louthrenoo, W, Takeuchi, T, Hao, Y, Morand, E, Lateef, A, Goldblatt, F, Cho, J, Navarra, S, Nikpour, M, Katsumata, Y, Luo, SF, Kikuchi, J, Chan, M, Sockalingam, S, Kandane-Rathnayake, R, Harigai, M, Zhang, Z, Golder, V, Li, Z, Hamijoyo, L, O'neill, S, An, Y   +26 more
core   +1 more source