Results 111 to 120 of about 35,016 (265)

World Health Organization classification of tumours of the breast 6th edition 2026

open access: yesHistopathology, EarlyView.
The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn   +47 more
wiley   +1 more source

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

open access: yesHistopathology, EarlyView.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak   +22 more
wiley   +1 more source

The prognostic value of tumour budding for survival in stage II and III colorectal cancer: a systematic review and meta‐analysis

open access: yesHistopathology, EarlyView.
This meta‐analysis demonstrates that high‐grade tumour budding is an independent prognostic factor in stage II–III colorectal cancer, associated with significantly worse disease‐free survival, overall survival and cancer‐specific survival. Aims Tumour budding (TB) has been recognized as an additional prognostic factor in the TNM (2017) and WHO (2019 ...
Yao Shu   +4 more
wiley   +1 more source

Does Local Excision Without Salvage Surgery Affect the Prognostic Outcome of Patients With Malignant Colorectal Polyp? A Long‐Term Survival Analysis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Management of malignant colorectal polyp has been a treatment dilemma for clinicians. This study aims to evaluate the long‐term survival outcome of patients with and without salvage surgery after local excision. Methods From January 2000 to December 2022, patients with T1 malignant colorectal polyp diagnosed after local ...
Vienna Man Wah Ng   +4 more
wiley   +1 more source

Early‐Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella   +8 more
wiley   +1 more source

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