Results 141 to 150 of about 35,016 (265)

Comparative Analysis of Incidental and Non‐Incidental Papillary Thyroid Microcarcinoma Outcomes: Implications on Management Recommendations

Clinical Endocrinology, Volume 105, Issue 1, Page 100-107, July 2026.
ABSTRACT Introduction Papillary thyroid microcarcinomas (PTMC) are defined by the World Health Organisation (WHO) as tumours measuring ≤ 10 mm. Incidental PTMCs, or lesions discovered postoperatively on histological examination, are less extensively studied compared with lesions diagnosed preoperatively through cytology, particularly in terms of ...
Emma A. Finnegan, Justin M. Hintze, Anne McGowan, James Gibney, Conall W. R. Fitzgerald, John Kinsella, Marie Louise Healy   +6 more
wiley   +1 more source

Multiplexed Immunofluorescent Characterization of T‐Cell and Myeloid Cell Populations Reveals Histologic Subtype Differences Within the Immunosuppressive Landscape of Human Basal Cell Carcinoma

Journal of Cutaneous Pathology, Volume 53, Issue 7, Page 624-632, July 2026.
ABSTRACT Background Basal cell carcinomas (BCCs) are thought to reside within an immunosuppressed tumor microenvironment, but a detailed characterization of BCC‐associated immune cells was lacking. Methods Utilizing multiplex immunohistochemistry (IHC) (Vectra Polaris, Akoya Biosciences), we designed two staining panels, targeting either T cells (CD3 ...
Alan S. Shen, Lauren E. Heusinkveld, Ajay Zalavadia, Andrelie Branicky, Sanjay Anand, Melissa Piliang, Edward V. Maytin   +6 more
wiley   +1 more source

The Value of the Preoperative Hematological Inflammatory Markers for Predicting Lymphovascular Invasion in Gastric Cancer. [PDF]

Immunotargets Ther
Li C, Wang Y, Liang S, Shi H, Mao X, Wang X, Mo D.   +6 more
europepmc   +1 more source

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Histopathology, Volume 89, Issue 1, Page 98-109, July 2026.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli, M. Elisa Vink‐Börger, Nanette S. van Roermund, Gesina van Lijnschoten, Chantal C.H.J. Kuijpers, Nicole C.T. van Grieken, Matteo Fassan, Joep E. Ijspeert, Rachel S. van der Post, Iris D. Nagtegaal   +9 more
wiley   +1 more source

Reassessment of Lymphovascular Invasion and Its Subtypes as Predictors of Prognosis and Recurrence in Gastric Cancer Using an Enhanced Detection Method. [PDF]

Cancers (Basel)
Liu J, Yang C, Li B, Sun Z, Liu D, Liu X, Chen H, Sun J, Li H, Sun Y, Zhao J, Wang X.   +11 more
europepmc   +1 more source

Preclinical and Virtual Models of Mucosal Melanoma: Bridging Translational Gaps in a Rare and Lethal Cancer

Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.
Integrated physical and virtual modeling provides a scalable framework to overcome sample scarcity, recapitulate mucosal melanoma biology, and accelerate translational discovery toward precision medicine. ABSTRACT Mucosal melanoma (MM) is a rare and lethal subtype of melanoma, disproportionately affecting Asian populations and exhibiting distinct ...
Xiangjie Jin, Yuhan Zhang, Yuantai Zhu, Zhiyuan Zhang, Chaoji Shi   +4 more
wiley   +1 more source

Topical Mitomycin C Chemotherapy After Surgical Resection of Conjunctival Amelanotic Melanoma in a Dog

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn, Koangyong Sung, Minwoo Jang, Kangmoon Seo, Seonmi Kang   +4 more
wiley   +1 more source

Prediction of Lymphovascular Invasion in Early-Stage Lung Adenocarcinoma Using Artificial Intelligence-Based Radiomics. [PDF]

Cancers (Basel)
Shimada Y, Harada K, Kudo Y, Park J, Matsubayashi J, Taguri M, Ikeda N.   +6 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ki67 and Lymphovascular Invasion as Histopathological Predictors of Residual Cancer Burden After Neoadjuvant Chemotherapy in Breast Cancer: A Retrospective Study. [PDF]

Diagnostics (Basel)
Carabas BA, Țǎpoi DA, Costache M.
europepmc   +1 more source