Results 251 to 260 of about 47,512 (271)

Periostin+ Stromal Cells Guide Lymphovascular Invasion by Cancer Cells

Cancer Research, 2023
Abstract Cancer cell dissemination to sentinel lymph nodes is associated with poor patient outcomes, particularly in breast cancer. The process by which cancer cells egress from the primary tumor upon interfacing with the lymphatic vasculature is complex and driven by dynamic interactions between cancer cells and stromal cells ...
Jamie L. Null, Dae Joong Kim, James V. McCann, Patcharin Pramoonjago, Jay W. Fox, Jianhao Zeng, Pankaj Kumar, Lincy Edatt, Chad V. Pecot, Andrew C. Dudley   +9 more
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Cancer Stromal Cells and Lymphovascular Invasion

2023
Breast cancer is the most commonly diagnosed cancer worldwide and is the leading cause of cancer-related mortality among women. Although existing therapeutic strategies are relatively effective at controlling localized disease, metastatic breast cancer that has spread to distant organs remains incurable and is responsible for the overwhelming majority ...
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Telomerase activity and lymphovascular invasion in breast cancer

European Journal of Surgical Oncology (EJSO), 2000
Telomerase is a ribonucleoprotein enzyme that plays an important role in cell immortalization and carcinogenesis. Lymphovascular invasion (LVI) is a fundamental step in the process of breast cancer metastasis and is recognized as an important prognostic factor in patients with breast cancer.Using a PCR-based assay, telomerase activity was determined in
K M, Mokbel, C N, Parris, M, Ghilchik, C N, Amerasinghe, R F, Newbold   +4 more
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Lymphovascular Invasion in Cutaneous Squamous Cell Carcinoma

Dermatologic Surgery
BACKGROUND Although there is a large body of literature regarding risk stratification and outcomes for perineural invasion (PNI) in cutaneous squamous cell carcinoma (cSCC), there is a relative paucity of studies exploring the role of lymphovascular invasion (LVI) in cSCC and a lack of clear evidence-based guidelines for how to
Michael P, Ryan, Frank T, Winsett, Andrew M, Armenta, Brandon P, Goodwin, Richard F, Wagner   +4 more
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Issues Relating to Lymphovascular Invasion in Breast Carcinoma

Advances in Anatomic Pathology, 2006
Lymphovascular invasion (LVI) by tumor cells is histologically evident in approximately 15% of invasive mammary duct carcinomas and is present in approximately 10% of cases with pathologically negative lymph nodes. LVI is indicative of unfavorable prognosis in the breast cancer-as manifested by increased local failure and reduced overall survival.
Syed A, Hoda, Rana S, Hoda, Scott, Merlin, Jamie, Shamonki, Michael, Rivera   +4 more
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Lymphovascular Invasion, as a Prognostic Marker in Patients with Invasive Breast Cancer

Acta Chirurgica Belgica, 2007
The markers of prognosis are used to predict the clinical course of disease and the outcome for patients with invasive breast cancer. Our aim is to investigate the relationship of peritumoural lymphovascular invasion (LVI) with well-known prognostic markers.Eighty-one surgically treated patients with invasive breast cancer were evaluated in this study ...
Gurleyik, G., Gurleyik, E., Aker, F., Aktekin, A., Emir, S., Gungor, O., Saglam, A.   +6 more
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Lymphangiogenesis and lymphovascular invasion diminishes prognosis in esophageal cancer

Surgery, 2013
Tumor-associated lymphatic networks are the primary routes for tumor cell dissemination and metastasis. Behind the background of possible lymphangiogenesis-associated therapies, the clinical impact of lymphangiogenesis (measured by lymphatic microvessel density [LMVD]) and specific lymphovascular invasion (LVI) in esophageal cancer remains unclear. The
Sebastian F, Schoppmann, Bettina, Jesch, Johannes, Zacherl, Martin F, Riegler, Julia, Friedrich, Peter, Birner   +5 more
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Prognostic significance of lymphovascular invasion in radical prostatectomy specimens

BJU International, 2012
Study Type – Prognosis (systematic review) Level of Evidence 1a What's known on the subject? and What does the study add? Prognostic factors such as serum PSA, tumor T stage, and Gleason grading are commonly ...
Jonathan, Ng, Aamer, Mahmud, Brenda, Bass, Michael, Brundage   +3 more
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EP945 Lymphovascular invasion in ovarian cancer

ePoster, 2019
Introduction/Background The aim of this study was to evaluate the impact of lymphovascular space invasion (LVSI) on overall survival (OS) and recurrence-free survival (RFS) in patients treated for epithelial ovarian cancer (EOC). Methodology Retrospective multicentre study of the research group FRANCOGYN between January 2001 and May 2016.
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Deep Learning Predicts Lymphovascular Invasion Status in Muscle Invasive Bladder Cancer Histopathology

Annals of Surgical Oncology
Lymphovascular invasion (LVI) is linked to poor prognosis in patients with muscle-invasive bladder cancer (MIBC). Accurately identifying the LVI status in MIBC patients is crucial for effective risk stratification and precision treatment. We aim to develop a deep learning model to identify the LVI status in whole-slide images (WSIs) of MIBC patients.A ...
Panpan Jiao, Shaolin Wu, Rui Yang, Xinmiao Ni, Jiejun Wu, Kai Wang, Xiuheng Liu, Zhiyuan Chen, Qingyuan Zheng   +8 more
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