Results 51 to 60 of about 2,729,303 (155)

Analytical and behavioral characterization of N‐ethyl‐N‐isopropyllysergamide (EIPLA), an isomer of N6–ethylnorlysergic acid N,N‐diethylamide (ETH‐LAD)

Drug Testing and Analysis, Volume 16, Issue 2, Page 187-198, February 2024.
An in‐depth analytical characterization of N‐ethyl‐N‐isopropyllysergamide (EIPLA) together with the evaluation of behavioral effects in mice using the head‐twitch response (HTR). EIPLA produced a dose‐dependent increase in HTR counts, with a median effective dose of 234.6 nmol/kg. The data suggest that the behavioral effects of EIPLA are reminiscent of
Simon D. Brandt, Pierce V. Kavanagh, Folker Westphal, Benedikt Pulver, Hannes M. Schwelm, Alexander Stratford, Volker Auwärter, Adam L. Halberstadt   +7 more
wiley   +1 more source

Effect of lysergic acid diethylamide and its brom analogue on arterial hypertension in the rat

, 1961
Subcutaneous administration of d-lysergic acid diethylamide (LSD) or 2-brom- d-lysergic acid diethylamide (BOL) markedly lowered the blood pressure of renal hypertensive rats.
George H. Fried, William Antopol, Stephen Sugaar, John Kalberer   +3 more
core   +1 more source

Risks for animal health related to the presence of ergot alkaloids in feed

EFSA Journal, Volume 22, Issue 1, January 2024.
Abstract The European Commission requested EFSA to provide an update of the 2012 Scientific Opinion of the Panel on Contaminants in the Food Chain (CONTAM) on the risks for animal health related to the presence of ergot alkaloids (EAs) in feed. EAs are produced by several fungi of the Claviceps and Epichloë genera.
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Jürgen Gropp, Patrick Mulder, Isabelle P. Oswald, Ruud Woutersen, Jose Ángel Gómez Ruiz, Elena Rovesti, Laurentius (Ron) Hoogenboom   +23 more
wiley   +1 more source

Additional file 3 of Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum

, 2022
Additional file 3: Figure S2. Disruption of estA in the easP knockout of M. brunneum.
Britton, Kelcie N., Steen, Chey R., Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.   +4 more
openaire   +1 more source

Additional file 2 of Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum

, 2022
Additional file 2: Table S1. Effect of easP mutation on radial growth, sporulation, and insect colonization.
Britton, Kelcie N., Steen, Chey R., Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.   +4 more
openaire   +1 more source

Additional file 1 of Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum

, 2022
Additional file 1: Figure S1. Disruption of the easP locus of M. brunneum.
Britton, Kelcie N., Steen, Chey R., Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.   +4 more
openaire   +1 more source

Simplified Analogues of Lysergic Acid. II. Derivatives of 3-(o-Tolyl)-n-propylarnine and 1-(o-Tolyl)isopropylamine

, 1959
Several N-alkyl derivatives of 3-(o-tolyl)-n-propylamine and 1-(o-tolyl)isopropyl-amine have been prepared and examined for lysergic acid-like activity.
JC Craig, B Moore, E Ritchie
core   +1 more source

Additive-free Pd/In2O3 Catalyzed N-methylation of Primary Amides using Formic Acid [PDF]

Here we report on the use of formic acid as a green and safe reagent for the N-methylation of primary amides in the presence of a Pd/In2O3 solid catalyst.
Caroline, Genre, Idir, Benaissa, Thibault, Cantat, Kassiogé, Dembélé   +3 more
core   +3 more sources

Lysergic acid diethylamide (LSD) [PDF]

, 2019
Lysergic acid diethylamide (LSD) is a drug known for its hallucinogenic properties especially at high doses and in recent years has been used as a pharmacological model to study the neurological substrate of psychosis, the effect of antipsychotics, and ...
Kehayova, Gabriela; Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Bulgaria, Marinov, Petko; Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Bulgaria, Zlateva, Snezha; Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Bulgaria   +2 more
core   +2 more sources

New method for the synthesis of 4-spirocyclopentane- and 4-spirocyclohexanenicotinic acid nitriles and amides

, 2021
The multicomponent condensation of cyclopentylidene- or cyclohexylidenemalononitrile, cyanoacetic acid amides or thioamides, and alkylating agents affords 4-spirocyclopentane- and 4-spirocyclohexanenicotinic acid nitriles and amides.
Khrustalev V.N., Nenajdenko V.G., Dorovatovskii P.V., Dyachenko I.V., Dyachenko V.D., I. V. Dyachenko, P. V. Dorovatovskii, V. G. Nenajdenko, V. D. Dyachenko, V. N. Khrustalev   +9 more
core   +1 more source