Results 41 to 50 of about 2,729,303 (155)

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Extraction and Identification of Clavine and Lysergic Acid Alkaloids from Morning Glories [PDF]

open access: yes, 1975
Author Institution: Department of Zoology and Microbiology, Ohio UniversityWITTERS, WELDON L. Extraction and identification of clavine and lysergic acid alkaloids from morning glories. Ohio J. Sci.
Witters, Weldon L.
core   +1 more source

Molecular and structural insights into the 5‐HT2C receptor as a therapeutic target for substance use disorders

open access: yesBritish Journal of Pharmacology, Volume 181, Issue 22, Page 4414-4429, November 2024.
Abstract Substance use disorder (SUD) is a chronic condition, with maintained abuse of a substance leading to physiological and psychological alterations and often changes in cognitive and social behaviours. Current therapies include psychotherapy coupled with medication; however, high relapse rates reveal the shortcomings of these therapies.
Maleesha Ubhayarathna   +3 more
wiley   +1 more source

A New Synthesis of Lysergic Acid

open access: yes, 2016
(±)-Lysergic acid (1) has been synthesized via an economical 8-step route from 4-bromoindole and isocinchomeronic acid without the need to protect the indole during the synthesis.
James B. Hendrickson (2273896)   +1 more
core   +1 more source

Epichloë fungal endophytes – a vital component for perennial ryegrass survival in New Zealand

open access: yesNew Zealand Journal of Agricultural Research, Volume 67, Issue 4, Page 451-468, August 2024.
ABSTRACT Pastoral agriculture underpins the New Zealand economy. Its success in generating export income is due to a mild and moist temperate climate, productive soils, innovative farmers supported by an effective research and development system, and an energy efficient production system based on year‐round grazing.
John R. Caradus
wiley   +1 more source

Mycotoxin contamination in organic and conventional cereal grain and products: A systematic literature review and meta‐analysis

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 23, Issue 3, May 2024.
Abstract There is still considerable controversy about the relative risk of mycotoxin exposure associated with the consumption of organic and conventional cereals. Using validated protocols, we carried out a systematic literature review and meta‐analyses of data on the incidence and concentrations of mycotoxins produced by Fusarium, Claviceps ...
Juan Wang   +10 more
wiley   +1 more source

Blockade of 5-Hydroxytryptamine Antidiuresis in Rats by 2-Bromlysergic Acid Diethylamide Tartrate and 1-Methyl-Lysergic Acid Butanolamide

open access: yes, 1963
The effects of two lysergic acid derivatives, 2-bromlysergic acid diethylamide ‘BOL 148’ and 1-methyl-lysergic acid butanolamide ‘UML 491’ on the antidiuresis induced by 5-hydroxytryptamine ‘5-HT’ has been studied in rats given a dose of 1 mg./kg.
A Chodera
core   +1 more source

A Short Synthesis of (−)‐6,7‐Secoagroclavine via Metal‐Free Reductive Coupling

open access: yesEuropean Journal of Organic Chemistry, Volume 27, Issue 13, April 2, 2024.
Two Csp3−Csp2 and Csp3−H bonds are formed on the same carbon atom by reacting the tosylhydrazone of chiral Uhle's ketone with 2,2‐dimethylethenylboronic acid. This metal‐free reductive coupling afforded an unexplored disconnection for the asymmetric synthesis of (−)‐6,7‐secoagroclavine. Abstract A concise, convergent, and enantioselective synthesis of (
Francesca Diotallevi   +2 more
wiley   +1 more source

Total Synthesis of (±)-Lysergic Acid, Lysergol, and Isolysergol by Palladium-Catalyzed Domino Cyclization of Amino Allenes Bearing a Bromoindolyl Group

open access: yes, 2016
Total Synthesis of (±)-Lysergic Acid, Lysergol, and Isolysergol by Palladium-Catalyzed Domino Cyclization of Amino Allenes Bearing a Bromoindolyl ...
Hiroaki Ohno (1457971)   +3 more
core   +1 more source

General Access to Clavine Alkaloids via a Rhodium(I)‐Catalyzed Diastereoselective Hayashi‐Miyaura Reaction

open access: yesAdvanced Synthesis &Catalysis, Volume 366, Issue 6, Page 1397-1404, March 19, 2024.
Abstract We report the development of the diastereoselective rhodium(I)‐catalyzed intramolecular conjugate addition (Hayashi‐Miyaura reaction) of robust and easily handled 4‐pinacolboronic ester D‐tryptophan derivatives tethering an activated alkene as the acceptor.
Giovanni Leoni   +2 more
wiley   +1 more source

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