Results 171 to 180 of about 8,921 (227)
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Lysergic Acid Diethylamide (LSD-25) Antagonists
A.M.A. Archives of Neurology & Psychiatry, 1958A. Introduction It has been shown1,2that 2 mg. of crude beef brain extract per milliliter of water blocks the usual effect of 2μg of LSD-25 per milliliter in the outside liquid on the Siamese fighting fish.* The experiments to be reported here are the study of a blocking effect probably produced by another mechanism: the development of tolerance3to ...
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Lysergic Acid Diethylamide (LSD-25)
A.M.A. Archives of Neurology & Psychiatry, 1958Although it is known that lysergic acid diethylamide (LSD-25) enters the brain, the mechanism by which LSD-25 acts to produce the psychotic patterns in man is unknown. Experiments which are designed to investigate the brain process in the intact animal might lead to a concept that could be developed to study the chemical process originating or ...
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Metabolism of lysergic acid diethylamide (LSD): an update
Drug Metabolism Reviews, 2019Lysergic acid diethylamide (LSD) is the most potent hallucinogen known and its pharmacological effect results from stimulation of central serotonin receptors (5-HT2). Since LSD is seen as physiologically safe compound with low toxicity, its use in therapeutics has been renewed during the last few years.
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Lysergic Acid Diethylamide (LSD-25) Antagonists
A.M.A. Archives of Neurology & Psychiatry, 1957A. Introduction At a meeting on psychochemicals arranged by the Battelle Memorial Institute in Columbus, Ohio, on Oct. 13, 1955, Dr. A. C. K. Elliott, of the Montreal Neurological Institute, mentioned the work of Florey. He pointed out that certain dialyzed aqueous brain extracts interfered with peripheral synaptic transmission. 1 One of us (H. A. A.)
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Antagonism of lysergic acid diethylamide (LSD)-induced hyperglycemia
International Journal of Neuropharmacology, 1964Abstract The hyperglycemic effect of LSD is reduced by 50% by pretreatment with pentolinium or phenoxybenzamine. Hydralazine pretreatment reinforces the hyperglycemic response to LSD. It is concluded that phenoxybenzamine acts at a central site to produce its antagonistic effect, since it did not affect the hyperglycemic response to infused ...
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Persistent Palinopsia Following Ingestion of Lysergic Acid Diethylamide (LSD)
Archives of Ophthalmology, 1996To identify a distinctive chronic visual complication of lysergic acid diethylamide (LSD) use.Description of the clinical findings in three patients with this disorder.A neuro-ophthalmology referral center.All three patients experienced prolonged afterimages (palinopsia) during LSD intoxication and have continued to be symptomatic up to 3 years after ...
A, Kawasaki, V, Purvin
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Lysergic Acid Diethylamide (LSD-25) and Ego Functions
Archives of General Psychiatry, 1963In 1947, Stoll32in Switzerland reported on the effects of D-lysergic acid diethylamide (LSD-25), an ergot derivative which can produce profound psychological effects in humans when it is given in minute doses. Since that time, a large volume of literature has grown up around this substance. LSD has been put to many uses.
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Mescaline and lysergic acid diethylamide (LSD) as discriminative stimuli
Psychopharmacologia, 1971The observation that a particular drug state may acquire the properties of a discriminative stimulus is explicable on the basis of drug-induced interoceptive cues. The present investigation sought to determine (a) whether the hallucinogens mescaline and LSD could serve as discriminative stimuli when either drug is paired with saline and (b) whether ...
I D, Hirschhorn, J C, Winter
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EXPERIMENTAL PHYSIOLOGICAL STUDIES WITH LYSERGIC ACID DIETHYLAMIDE (LSD-25)
Archives of Neurology And Psychiatry, 1951STOLL1studied the effects of lysergic acid diethylamide (LSD-25) in both psychotic and normal subjects. Condrau2and others reported their results of administration of lysergic acid diethylamide to various types of subjects and in general confirmed the findings of Stoll.
G R, FORRER, R D, GOLDNER
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Lysergic Acid Diethylamide (LSD 25) and behaviour therapy
Behaviour Research and Therapy, 1964Abstract This paper deals with the problems involved in the treatment of complex neurotic conditions. A seventh feature is added to Wolpe's list of the six features that make a neurosis complex. The use of Lysergic Acid Diethylamide (LSD 25) in the treatment of such difficult cases is discussed and three cases are presented.
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