Results 41 to 50 of about 37,615 (246)

Assessing the Feasibility of Employing a Combination of a Bacteriophage-Derived Endolysin and Spore Germinants to Treat Relapsing Clostridioides difficile Infection

Microorganisms, 2023
Clostridioides difficile is a Gram-positive, anaerobic, spore-forming bacillus and is a major cause of healthcare-associated infections. Whereas the vegetative form of the pathogen is susceptible to treatment with antibiotics, its ability to persist in ...
Khalid Alyahya, Les Baillie
doaj   +1 more source

Cell wall integrity signaling regulates cell wall-related gene expression in Chlamydomonas reinhardtii

Scientific Reports, 2019
An intact cell wall is critical for cellular interactions with the environment and protecting the cell from environmental challenges. Signaling mechanisms are necessary to monitor cell wall integrity and to regulate cell wall production and remodeling ...
Evan Cronmiller, Deepak Toor, Nai Chun Shao, Thamali Kariyawasam, Ming Hsiu Wang, Jae-Hyeok Lee   +5 more
doaj   +1 more source

May the Phage be With You? Prophage-Like Elements in the Genomes of Soft Rot Pectobacteriaceae: Pectobacterium spp. and Dickeya spp.

Frontiers in Microbiology, 2019
Soft Rot Pectobacteriaceae (SRP; Pectobacterium spp. and Dickeya spp., formerly known as pectinolytic Erwinia spp.) are necrotrophic bacterial pathogens infecting a large number of plant species worldwide, including agriculturally-important crops ...
Robert Czajkowski
doaj   +1 more source

Bacterial resistance to antimicrobial agents and its impact on veterinary and human medicine [PDF]

, 2016
Background Antimicrobial resistance has become a major challenge in veterinary medicine, particularly in the context of bacterial pathogens that play a role in both humans and animals.
Aarestrup, Abedon, Arais, Becker, Bikard, Blondeau, Brackman, Bradford, Brandenburg, Brogden, Burrus, Bush, Bush, Bywater, Chopra, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute, Connell, Couto, Cuny, D'Costa, Damborg, Duijkeren, Ewers, Ewers, Falgenhauer, Feßler, Fischetti, Fuente-Núñez, Giessen, Goh, Grobbel, Grobbel, Groves, Guardabassi, Hall, Harada, Harrison, Hill, Hillier, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC), Kadlec, Kadlec, Kadlec, Kadlec, Kehrenberg, Köck, Laube, Lefebvre, Lindsay, Lloyd, Long, Lyon, Lüthje, Maaland, Maddox, Magiorakos, Mascaretti, McCarthy, McCarthy, McNulty, Michael, Michael, Michael, Moodley, Mueller, Nienhoff, Nobrega, O'Neill, Paterson, Perreten, Poole, Putman, Ramirez, Redgrave, Richter, Riesenberg, Roberts, Roberts, Roberts, Ruiz, Rule, Schaufler, Schmiedel, Schneider, Schuch, Schultz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Schwarz, Scott, Shen, Sing, Soares, Sobral, Thandar, Thomas, Tsonos, van, von, Walther, Wang, Weiß, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Wendlandt, Werckenthin, Westgarth, Westgarth, White, Wu, Zervos, Zhao, Zurek   +123 more
core   +3 more sources

Suppressors of lysine codons may be misacylated lysine tRNAs [PDF]

Journal of Bacteriology, 1983
We describe a novel class of missense suppressors that read the codons for lysine at two positions (211 and 234) in the trpA polypeptide of Escherichia coli. The suppressor mutations are highly linked to lysT, a gene for lysine tRNA. The results suggest that the suppressors are misacylated lysine tRNAs that carry glycine or alanine.
E J, Murgola, F T, Pagel
openaire   +2 more sources

Controlled overproduction of proteins by lactic acid bacteria [PDF]

, 1997
Lactic acid bacteria are widely used in industrial food fermentations, contributing to flavour, texture and preservation of the fermented products. Here we describe recent advances in the development of controlled gene expression systems, which allow the
Kleerebezem, Michiel,, Kuipers, Oscar P.,, Ruyter, Pascalle G.G.A. de,, Vos, Willem M. de,   +3 more
core   +3 more sources

Molecular Characterisation of Bacteriophage K Towards Applications for the Biocontrol of Pathogenic Staphylococci [PDF]

, 2006
End of project reportThe aim of this work was to characterise staphylococcal bacteriophage (a bacterial virus) and to assess their potential as therapeutic agents against pathogenic strains of Staphylococcus aureus, particularly mastitis-causing strains.
Coffey, Aidan, Fitzgerald, Gerald F, Flynn, James, Meaney, William J, O'Flaherty, Sarah, Ross, R Paul   +5 more
core  

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Effect of Nk-lysin peptides on bacterial growth, MIC, antimicrobial resistance, and viral activities

Animal Biotechnology
NK-lysins from chicken, bovine and human are used as antiviral and antibacterial agents. Gram-negative and gram-positive microorganisms, including Streptococcus pyogenes, Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Klebsiella oxytoca,
Haitham A. Yacoub, Maged Mostafa Mahmoud, Ahmed M. Al-Hejin, Turki S. Abujamel, Shams Tabrez, Sherif Abd-Elmaksoud   +5 more
doaj   +1 more source

Engineering of Phage-Derived Lytic Enzymes: Improving Their Potential as Antimicrobials

Antibiotics, 2018
Lytic enzymes encoded by bacteriophages have been intensively explored as alternative agents for combating bacterial pathogens in different contexts. The antibacterial character of these enzymes (enzybiotics) results from their degrading activity towards
Carlos São-José
doaj   +1 more source