Results 211 to 220 of about 510,795 (264)
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Lysine kinetics at graded lysine intakes in young men
American Journal of Clinical Nutrition, 1986Healthy young men participated in a study designed to explore the effects of decreasing dietary lysine content on plasma amino acid concentrations and lysine kinetics, studied with L-[1-13C]lysine as tracer. Diets provided adequate energy and the equivalent (N X 6.25) of 0.8 g protein kg-1.day-1 as a synthetic L-amino acid mixture simulating egg ...
V R Young, Dm Bier, D M Bier
exaly +3 more sources
Formation of thymine-lysine and cytosine-lysine adducts in DNA-lysine photoconjugate
Journal of Photochemistry and Photobiology B: Biology, 1995Lysine was covalently conjugated to calf thymus DNA by irradiation with UV light (wavelength, 253.7 nm). The results showed monofunctional covalent photobinding of lysine molecules with bases in DNA. Only the epsilon-amino group of lysine participated in the photoconjugation reaction. Thymine and cytosine were modified by 60% and 25% respectively.
N, Islam, R, Ali
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Antibacterial lysine analogs that target lysine riboswitches
Nature Chemical Biology, 2006Lysine riboswitches are bacterial RNA structures that sense the concentration of lysine and regulate the expression of lysine biosynthesis and transport genes. Members of this riboswitch class are found in the 5' untranslated region of messenger RNAs, where they form highly selective receptors for lysine.
Kenneth F, Blount +4 more
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Lysine−Bisglycidol Conjugates as Novel Lysine Cationic Surfactants
Langmuir, 2009The synthesis of a novel class of lysine-based cationic amphiphilic derivatives of the type N(epsilon),N(epsilon)'-bis(n-acyloxypropyl)-l-lysine methyl ester salts combining several hydroxyl functions and aliphatic chains of 12 or 14 carbon atoms is described. The compounds have one, two, three, and four alkyl chains.
Pinazo Gassol, Aurora +5 more
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A lysine dehydrogenase-based electrode for biosensing of l-lysine
Biosensors and Bioelectronics, 1992An amperometric biosensor for L-lysine based on the recently isolated enzyme lysine dehydrogenase is described. Immobilization of the enzyme onto a platinum electrode is achieved via entrapment within a gelatin support on a cellulose membrane. Anodic detection (at 0.4 V vs.
Dempsey, E +4 more
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Advanced Delivery Systems Based on Lysine or Lysine Polymers
Molecular Pharmaceutics, 2021Polylysine and materials that integrate lysine form promising drug delivery platforms. As a cationic macromolecule, a polylysine polymer electrostatically interacts with cells and is efficiently internalized, thereby enabling intracellular delivery. Although polylysine is intrinsically pH-responsive, the conjugation with different functional groups ...
Saeed Manouchehri +3 more
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Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation
ACS Chemical Biology, 2022Genetic code expansion has proven invaluable to the elucidation of functions of defined protein modifications through the site-specific incorporation of noncanonical amino acids. The use of nonhydrolyzable derivatives of post-translational modifications can greatly increase site stoichiometry and half-life.
Gregory M. Miller +4 more
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Archives of Dermatology, 1985
To the Editor.— In the JanuaryArchives, DiGiovanna and Blank 1 reported failure of lysine in frequently recurrent herpes simplex infection. Caution is urged in the interpretation of their results. The L-isomer allosterically inhibits herpes in vitro, 2,3 while the D-isomer is biologically inactive.
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To the Editor.— In the JanuaryArchives, DiGiovanna and Blank 1 reported failure of lysine in frequently recurrent herpes simplex infection. Caution is urged in the interpretation of their results. The L-isomer allosterically inhibits herpes in vitro, 2,3 while the D-isomer is biologically inactive.
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