Results 301 to 310 of about 656,192 (343)
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Advanced Delivery Systems Based on Lysine or Lysine Polymers
Molecular Pharmaceutics, 2021Polylysine and materials that integrate lysine form promising drug delivery platforms. As a cationic macromolecule, a polylysine polymer electrostatically interacts with cells and is efficiently internalized, thereby enabling intracellular delivery. Although polylysine is intrinsically pH-responsive, the conjugation with different functional groups ...
Saeed Manouchehri +3 more
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Archives of Dermatology, 1985
To the Editor.— In the JanuaryArchives, DiGiovanna and Blank 1 reported failure of lysine in frequently recurrent herpes simplex infection. Caution is urged in the interpretation of their results. The L-isomer allosterically inhibits herpes in vitro, 2,3 while the D-isomer is biologically inactive.
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To the Editor.— In the JanuaryArchives, DiGiovanna and Blank 1 reported failure of lysine in frequently recurrent herpes simplex infection. Caution is urged in the interpretation of their results. The L-isomer allosterically inhibits herpes in vitro, 2,3 while the D-isomer is biologically inactive.
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Trifluoroacetyl Lysine as a Bromodomain Binding Mimic of Lysine Acetylation
ACS Chemical Biology, 2022Genetic code expansion has proven invaluable to the elucidation of functions of defined protein modifications through the site-specific incorporation of noncanonical amino acids. The use of nonhydrolyzable derivatives of post-translational modifications can greatly increase site stoichiometry and half-life.
Gregory M. Miller +4 more
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Lysine−Bisglycidol Conjugates as Novel Lysine Cationic Surfactants
Langmuir, 2009The synthesis of a novel class of lysine-based cationic amphiphilic derivatives of the type N(epsilon),N(epsilon)'-bis(n-acyloxypropyl)-l-lysine methyl ester salts combining several hydroxyl functions and aliphatic chains of 12 or 14 carbon atoms is described. The compounds have one, two, three, and four alkyl chains.
Pinazo Gassol, Aurora +5 more
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N-Substituted Lysines as Sources of Lysine in Nutrition
1978Twenty seven alpha-N- and epsilon-N-substituted derivatives of lysine belonging to eight different classes: (1) natural dipeptides, (2) alpha-N-acyl-, (3)epsilon-N-acyl-, (4)epsilon-N-(alpha-amino acyl)-, (5)epsilon-N-(omega-amino acyl)-, (6)alpha-N-epsilon-N-di-amino acyl-, (7)epsilon-N-acylglycyl- and (8)Schiff's bases were synthesized. The "in vitro"
P A, Finot +3 more
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A lysine dehydrogenase-based electrode for biosensing of l-lysine
Biosensors and Bioelectronics, 1992An amperometric biosensor for L-lysine based on the recently isolated enzyme lysine dehydrogenase is described. Immobilization of the enzyme onto a platinum electrode is achieved via entrapment within a gelatin support on a cellulose membrane. Anodic detection (at 0.4 V vs.
Dempsey, E +4 more
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Lysine Infusion in Cystinuria: Theoretical Renal Thresholds for Lysine
Clinical Science, 19731. The renal handling of lysine was studied during the intravenous infusion of a lysine load given in such a way that the plasma lysine concentration was constantly increasing. Theoretical renal thresholds, and maximum rates of renal tubular reabsorption of lysine, have been determined in three normal adults, five homozygous cystinuric patients, and ...
F T, Lester, D C, Cusworth
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Lysine kinetics at graded lysine intakes in young men
The American Journal of Clinical Nutrition, 1986Healthy young men participated in a study designed to explore the effects of decreasing dietary lysine content on plasma amino acid concentrations and lysine kinetics, studied with L-[1-13C]lysine as tracer. Diets provided adequate energy and the equivalent (N X 6.25) of 0.8 g protein kg-1.day-1 as a synthetic L-amino acid mixture simulating egg ...
C N, Meredith +4 more
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Archives of Biochemistry and Biophysics, 1972
Abstract The metabolism of l -lysine, l -pipecolate, and saccharopine was studied in rabbits. The results indicated the existence of the same metabolic pathways as have been delineated in other species. The rabbit differed from the other species studied previously since saccharopine, l -pipecolate, and d -lysine were all readily converted to CO 2
J A, Grove +3 more
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Abstract The metabolism of l -lysine, l -pipecolate, and saccharopine was studied in rabbits. The results indicated the existence of the same metabolic pathways as have been delineated in other species. The rabbit differed from the other species studied previously since saccharopine, l -pipecolate, and d -lysine were all readily converted to CO 2
J A, Grove +3 more
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Amino Acids, 2015
Determining the bioavailability of lysine in foods and feedstuffs is important since lysine is often the first limiting indispensable amino acid in diets for intensively farmed livestock (pigs and poultry) and also in many cereal-based diets consumed by humans.
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Determining the bioavailability of lysine in foods and feedstuffs is important since lysine is often the first limiting indispensable amino acid in diets for intensively farmed livestock (pigs and poultry) and also in many cereal-based diets consumed by humans.
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