Results 21 to 30 of about 2,947 (122)

Efficacy of a Spray Compound Containing a Pool of Collagen Precursor Synthetic Amino Acids (L-Proline, L-Leucine, L-Lysine and Glycine) Combined with Sodium Hyaluronate to Manage Chemo/Radiotherapy-Induced Oral Mucositis: Preliminary Data of an Open Clinical Trial

International Journal of Immunopathology and Pharmacology, 2010
Oral mucositis (OM) is a very frequent and potentially severe complication experienced by patients receiving chemotherapy and/or radiotherapy, which often leads to significant morbidity and mortality, and decreased quality of life, and is very costly. Despite its severity and prevalence, there is no standard recognised management today. The aim of this
Colella, G, Cannavale, R, Vicidomini, A, RINALDI, Gaetana, COMPILATO, Domenico, CAMPISI, Giuseppina   +5 more
openaire   +4 more sources

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid, Vickie Lacroix, Ekaterina Ovtchinnikova, Sophie Thenet, Marie Carriere, Frédérick Barreau, Emmanuel Mas   +6 more
wiley   +1 more source

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source

The Inertness of the Lysozyme Template: Assessing the Structural Impact of Silicification Byproducts and Precursors

Chemistry–Methods, Volume 6, Issue 8, August 2026.
Lysozyme templates bioinspired silicification via localized electrostatic pooling, at variance with disordered peptides, require counterion‐driven coacervation. Small‐angle X‐ray scattering and NMR spectroscopy reveal that the folded lysozyme template remains structurally inert and monomeric in the presence of silicic acid mimics and alcohol byproducts.
Tozivepi Aaron Munyayi, Francesco Bruno, Letizia Fiorucci, Vincenzo Mangini, Francesco Scattarella, Cinzia Giannini, Jose Malanho Da Silva, Giacomo Parigi, Angelo Gallo, Enrico Ravera   +9 more
wiley   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

An Experimental and Educational Framework for Nonenzymatic Polyphenol Conversion: Bridging Molecular Food Science and Materials Technology through Organic Chemistry

ChemFoodChem, Volume 2, Issue 2, June 2026.
Gallic acid serves as an ideal bridge between fundamental sciences and gastronomy, as its presence as a plant polyphenol moiety. Its symmetrical, multifunctional phenolic structure makes it a perfect educational building block for linking organic chemistry both to food science and material design.
Antonio Radesco, Matteo Spagnuolo, Maria Calasso, Danilo Vona, Maria De Angelis   +4 more
wiley   +1 more source

Intrapopulation Metabolic Variation Reflects Growth Differences: A Cross‐Sectional Study on Gammarides

Ecology and Evolution, Volume 16, Issue 5, May 2026.
For the first time in Gammarus insensibilis, a single‐organism 1H NMR metabolomics approach was applied to investigate the intrapopulation variability in growth trajectories showing how divergent size classes, despite being of the same age, reflect alternative resource‐allocation strategies.
Federica De Castro, Ludovico Lezzi, Milad Shokri, Laura Del Coco, Francesco Paolo Fanizzi, Alberto Basset   +5 more
wiley   +1 more source

Reversing Lanmodulin's Metal‐Binding Sequence in Short Peptides Surprisingly Increases the Lanthanide Affinity

Angewandte Chemie, Volume 137, Issue 46, November 10, 2025.
Accidentally reversing the lanthanide‐binding sequences of lanmodulin‐inspired short peptides lead to the serendipitous discovery of a set of peptides with a one order of magnitude higher lanthanide‐binding affinity than the uncapped peptides synthesised in the correct direction.
Sophie M. Gutenthaler‐Tietze, Jerome Kretzschmar, Satoru Tsushima, Robin Steudtner, Björn Drobot, Lena J. Daumann   +5 more
wiley   +2 more sources

Effects of Amino Acid Priming Applications Enhances Salt Tolerance in Safflower (Carthamus tinctorius L.)

Journal of Agronomy and Crop Science, Volume 212, Issue 3, May 2026.
ABSTRACT This study was conducted to determine the effects of priming safflower cultivar (Askon 42) with various doses (0, 5, 10, 15 mM) of 3 different amino acids (methionine, lysine, tyrosine) against salt stress (0, 50, 100, 150 mM) in terms of investigated parameters.
Mehtap Gürsoy
wiley   +1 more source

Synthesis of Peptides, Peptide Nucleic Acid Components, and Other Biogenic Compounds From a Three‐Component Prebiotic Mixture

Chemistry – A European Journal, Volume 32, Issue 9, 2 March 2026.
High‐energy proton irradiation of a formamide–diaminomaleonitrile–glycine system in the presence of meteorites produces a broad spectrum of biogenic compounds, including nucleobases, nucleosides, peptides, and nucleobase–peptide conjugates, highlighting a chemically plausible prebiotic network.
Bruno Mattia Bizzarri, Rosangela Santalucia, Eleonora Mancin, Mikhail Kapralov, Eugene Krasavin, Raffaele Saladino, Ernesto Di Mauro   +6 more
wiley   +1 more source