Results 111 to 120 of about 1,236,497 (367)

Stressed fibrin lysis [PDF]

open access: yesJournal of Thrombosis and Haemostasis, 2011
See also Varju I, Sotonyi P, Machovich R, Szabo L, Tenekedjiev K, Silva MMCG, Longstaff C, Kolev K. Hindered dissolution of fibrin formed under mechanical stress. This issue, pp 979–86.
openaire   +3 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Isolation and Characterization of Lytic Phages Infecting Clinical Klebsiella pneumoniae from Tunisia

open access: yesAntibiotics
Background: Klebsiella pneumoniae is an opportunistic pathogen that causes a wide range of infections worldwide. The emergence and spread of multidrug-resistant clones requires the implementation of novel therapeutics, and phages are a promising approach.
Donia Mourali   +6 more
doaj   +1 more source

Absence of evidence for viral infection in colony-embedded cyanobacterial isolates from the Curonian Lagoon

open access: yesOceanologia, 2014
The aim of the present study was to assess the frequency of viral infections in colony-embedded cells of the cyanobacteria Aphanizomenon flos-aquae and Microcystis aeruginosa collected from the brackish Curonian Lagoon. Natural and mitomycin C-treated A.
Sigitas Sulcius   +2 more
doaj   +1 more source

Model comparison and assessment for single particle tracking in biological fluids [PDF]

open access: yesarXiv, 2014
State-of-the-art techniques in passive particle-tracking microscopy provide high-resolution path trajectories of diverse foreign particles in biological fluids. For particles on the order of 1 micron diameter, these paths are generally inconsistent with simple Brownian motion.
arxiv  

Boolean Models of Bistable Biological Systems [PDF]

open access: yes, 2009
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex differential equations models. The motivation for this work comes from mathematical systems biology.
arxiv   +1 more source

Spatial heterogeneity and peptide availability determine CTL killing efficiency in vivo [PDF]

open access: yes, 2014
The rate at which a cytotoxic T lymphocyte (CTL) can survey for infected cells is a key ingredient of models of vertebrate immune responses to intracellular pathogens. Estimates have been obtained using in vivo cytotoxicity assays in which peptide-pulsed
A Wiedemann   +46 more
core   +3 more sources

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Viral Regulation on Bacterial Community Impacted by Lysis-Lysogeny Switch: A Microcosm Experiment in Eutrophic Coastal Waters

open access: yesFrontiers in Microbiology, 2019
Marine viruses are major drivers of global biogeochemical cycles and energy fluxes, yet the importance of viral impacts on the succession and diversity of the bacterial community remains largely unexplored.
Xiaowei Chen   +5 more
doaj   +1 more source

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