Results 71 to 80 of about 1,236,497 (367)

Love and Friendship in the Lysis and the Symposium: Human and Divine [PDF]

open access: yes, 2008
The paper claims that we cannot understand properly Platonic conception of love and friendship unless we read the Lysis in the light of the Symposium and vice verse.
Jinek, Jakub
core  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Comparison of Lysis and Detachment Sample Preparation Methods for Cultured Triple-Negative Breast Cancer Cells Using UHPLC–HRMS-Based Metabolomics

open access: yesMetabolites, 2022
Dysregulation of cellular metabolism is now a well-recognized hallmark of cancer. Studies investigating the metabolic features of cancer cells have shed new light onto processes in cancer cell biology and have identified many potential novel treatment ...
Blake R. Rushing   +2 more
doaj   +1 more source

On the isolation of TI-plasmid from Agrobacterium tumefaciens [PDF]

open access: yes, 1976
An efficient lysis method for Agrobacterium cells was developed, which allows a reproducible isolation of the tumor inducing (TI)-plasmid. The lysis method is based on the sensitivity of this bacterium to incubation with lysozyme, n-dodecylamine,EDTA ...
Dons, Johannes JM   +7 more
core   +2 more sources

Intracerebral Hematoma Lysis

open access: yesJournal of Neurosurgery, 2007
Object Currently no adequate surgical treatment exists for spontaneous intracerebral hemorrhage (ICH). Implantable polymers can be used effectively to deliver therapeutic agents to the local site of the pathological process, thus reducing adverse systemic effects.
Rohde, Veit, Samadani, Uzma
openaire   +3 more sources

Bacterial lysis and antiseptics [PDF]

open access: yesJournal of Hygiene, 1948
When a number of organisms are exposed in early rapidly multiplying broth cultures to minimally effective bacteriostatic concentrations of a number of antiseptics, almost complete lysis may be demonstrated.When older cultures are exposed to low concentrations, or young cultures to strong concentrations, lysis does not occur in many cases.The lytic ...
G. D. Lumb, R. J. V. Pulvertaft
openaire   +3 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Characterization and Application of a Lytic Phage D10 against Multidrug-Resistant Salmonella

open access: yesViruses, 2021
Salmonella is a widely distributed foodborne pathogen that is a serious threat to human health. The accelerated development of drug resistance and the increased demand for natural foods invoke new biocontrol agents to limit contamination by multidrug ...
Zhiwei Li   +7 more
doaj   +1 more source

An Abstraction Theory for Qualitative Models of Biological Systems [PDF]

open access: yesEPTCS 40, 2010, pp. 23-38, 2010
Multi-valued network models are an important qualitative modelling approach used widely by the biological community. In this paper we consider developing an abstraction theory for multi-valued network models that allows the state space of a model to be reduced while preserving key properties of the model.
arxiv   +1 more source

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