Results 91 to 100 of about 8,505 (197)
The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases [PDF]
, 2002 The protein SpoIVB plays a key role in signaling in the sigma (K) checkpoint of Bacillus subtilis. This regulatory mechanism coordinates late gene expression during development in this organism and we have recently shown SpoIVB to be a serine peptidase ...
Brannigan, J A, Cutting, S M, Hoa, N T
core +2 more sources
DNA Packaging Specificity in the λ‐Like Phages: Gifsy‐1
Molecular Microbiology, Volume 122, Issue 4, Page 491-503, October 2024.Dimeric λ TerS and chimera transition points. The N‐termini of each TerS derives from a λ‐like source phage: Gifsy‐1, 21, and N15 (labeled arrows). The N‐terminus includes the winged‐helix‐turn‐helix (HTH) DNA‐binding motif that confers the source phage's DNA packaging specificity.
Michael Feiss, Jean Arens Sippy
wiley +1 more source
Phages for Phage Therapy: Isolation, Characterization, and Host Range Breadth
Pharmaceuticals, 2019 For a bacteriophage to be useful for phage therapy it must be both isolated from the environment and shown to have certain characteristics beyond just killing strains of the target bacterial pathogen.
Paul Hyman
doaj +1 more source
Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1 [PDF]
, 2017 In the past 30 years,Salmonella bloodstream infections have become a significant health problem in sub-Saharan Africa and are responsible for the deaths of anestimated 390,000 people each year.
Aertsen, A +8 more
core +3 more sources
Advanced Science, Volume 11, Issue 30, August 14, 2024.Engineered bacteria specifically refer to advanced physiochemical or genetic modifications of diagnostic bacteria, which can compensate for the shortcomings of natural strains. After engineering, these diagnostic bacteria are encouraged to lyse tumors, regulate immunity and cellular communication such immune cells, influence metabolic pathways ...
Xia Lin +4 more
wiley +1 more source
mSystems, 2020 A diverse set of prophage-mediated mechanisms protecting bacterial hosts from infection has been recently uncovered within cluster N mycobacteriophages isolated on the host, Mycobacterium smegmatis mc2155.
Catherine M. Mageeney +7 more
doaj +1 more source
MicrobiologyOpen, Volume 13, Issue 4, August 2024.This study reveals that several enzymes involved in the central metabolism of Bacteroides fragilis are regulated by protein‐protein interactions with pirin proteins. We observed changes in susceptibility to the antimicrobials metronidazole and amixicile in various metabolic mutants.
Andrea M. Gough +8 more
wiley +1 more source
Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
, 2017 Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob +2 more
core +1 more source
Microbial Biotechnology, Volume 17, Issue 8, August 2024.Bacterial infections are predicted to be the main cause of death by 2050, and persister cells often form during periods of lethal stress. Here, we show phage infections generate persister cells, and these persisters may undermine phage therapy. Abstract Arguably, the greatest threat to bacteria is phages.
Laura Fernández‐García +6 more
wiley +1 more source
Population fitness and the regulation of Escherichia coli genes by bacterial viruses.
PLoS Biology, 2005 Temperate bacteriophage parasitize their host by integrating into the host genome where they provide additional genetic information that confers higher fitness on the host bacterium by protecting it against invasion by other bacteriophage, by increasing ...
Ying Chen +4 more
doaj +2 more sources