Results 111 to 120 of about 39,604 (271)

Skin microbiome engineering: Challenges and opportunities in skin diseases treatment

iMetaOmics, EarlyView.
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley   +1 more source

Prevalence, Host Range, and Comparative Genomic Analysis of Temperate Ochrobactrum Phages

Frontiers in Microbiology, 2017
Ochrobactrum and Brucella are closely related bacteria that populate different habitats and differ in their pathogenic properties. Only little is known about mobile genetic elements in these genera which might be important for survival and virulence ...
Claudia Jäckel, Stefan Hertwig, Holger C. Scholz, Karsten Nöckler, Jochen Reetz, Jens A. Hammerl   +5 more
doaj   +1 more source

Phage‐mediated horizontal transfer of Salmonella enterica virulence genes with regulatory feedback from the host

iMeta, EarlyView.
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She, Demeng Tan, Jose Luis Balcazar, Ville‐Petri Friman, Danrui Wang, Dong Zhu, Mao Ye, Mingming Sun, Shujian Yuan, Feng Hu   +9 more
wiley   +1 more source

Variability and host density independence in inductions-based estimates of environmental lysogeny. [PDF]

, 2017
Temperate bacterial viruses (phages) may enter a symbiosis with their host cell, forming a unit called a lysogen. Infection and viral replication are disassociated in lysogens until an induction event such as DNA damage occurs, triggering viral-mediated ...
Bailey, Barbara, Boling, Lance, Breitbart, Mya, Cobián-Güemes, Ana, Del Campo, Javier, Edwards, Rob, Felts, Ben, Grasis, Juris, Haas, Andreas F, Katira, Parag, Kelly, Linda Wegley, Knowles, Ben, Luque, Antoni, Nulton, Jim, Paul, Lauren, Peters, Gregory, Robinett, Nate, Rohwer, Forest, Sandin, Stuart, Segall, Anca, Silveira, Cynthia, Youle, Merry   +21 more
core   +1 more source

Light‐Driven Structural Detachment and Controlled Release in Smart Antibacterial Multilayer Platforms

Macromolecular Materials and Engineering, EarlyView.
This study presents a multilayer system (MS) based on benzophenone‐modified polydimethylsiloxane (PDMS) and a thermo‐responsive core incorporating P(NIPAAm‐co‐NIPMAAm), gelatin, and gelatin methacrylate (GelMA). The photothermal properties of gold nanorods, together with the thermal sensitivity of hydrogel, enable controlled detachment and release of ...
Zuzanna J. Krysiak, Daniel Rybak, Tetuko Kurniawan, Anna Zakrzewska, Filippo Pierini   +4 more
wiley   +1 more source

Adsorbable and Antimicrobial Amphiphilic Block Copolymers with Enhanced Biocompatibility

Macromolecular Materials and Engineering, EarlyView.
Permanently implanted biomaterials are prone to attract microorganisms and thus represent niches for infections in vivo. Absorbable, antimicrobial polymers have emerged as a promising option. To improve the compatibility of adsorbable antimicrobial polymers with human cells, the block composition of the polycationic segment is modified regarding the ...
Cornelia Wolf‐Brandstetter, Rafael Methling, Dirk Kuckling   +2 more
wiley   +1 more source

A Short Introduction to Bacteriophages

Trends in Peptide and Protein Sciences, 2016
First discovered in the 19th century, bacteriophages (phages) are bacterial viruses and the most widespread entities on earth. Phages have multiple important roles in maintaining the bacterial population, carbon cycling, bacterial pathogenicity, and ...
Ramin Mazaheri Nezhad Fard
doaj   +1 more source

Transient-mediated fate determination in a transcriptional circuit of HIV [PDF]

, 2007
Steady-state behavior and bistability have been proposed as mechanisms for decision-making in gene circuits. However, transient gene expression has also been proposed to control cell fate with the decision arbitrated by the lifetime of the expression ...
Leor Weinberger, Michael Simpson, Roy D. Dar   +2 more
core   +1 more source

Within‐Host Mathematical Modeling of Antibiotic‐phage Treatments on Lysogenic and Nonlysogenic Bacteria Dynamics

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Bacteriophages, or phages (viruses of bacteria), play significant roles in shaping the diversity of bacterial communities within the human gut. A phage‐infected bacterial cell can either immediately undergo lysis (virulent/lytic infection) or enter a stable state within the host as a prophage (lysogeny) until a trigger event, called prophage ...
Hyacinthe M. Ndongmo Teytsa, Ousmane Seydi, Berge Tsanou, Ramsès Djidjou‐Demasse   +3 more
wiley   +1 more source

Cryptic Lysogeny in Proteus mirabilis

Journal of General Virology, 1973
Summary Proteus mirabilis strains 13 and 5006 on rare occasions liberate temperate phages, 13M and 5006M, which may reinfect parent strains. These prophages are not inducible but the probability of phage liberation may be increased by growth in nitrosoguanidine. P. mirabilis strain 34 liberates a phage, φ34, spontaneously. Strain 34 is doubly lysogenic
openaire   +3 more sources