Results 91 to 100 of about 24,966 (212)
The particle with high surface hydrophilicity exhibits strong thermophoretic attraction, as its dense hydration layer enhances the role of interfacial water molecules in determining thermophoretic mobility over other ionic effects. This finding elucidates the mechanism underlying the robust thermophoretic accumulation of Escherichia coli in high ...
Seungyeop Kang +3 more
wiley +1 more source
Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh +7 more
wiley +1 more source
Bacterial resistance to temperate phage is influenced by the frequency of lysogenic establishment
Summary: Temperate phages can shape bacterial community dynamics and evolution through lytic and lysogenic life cycles. In response, bacteria that resist phage infection can emerge.
Hiba Baaziz +3 more
doaj +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
ABSTRACT Cerebrospinal fluid (CSF) is drained into the systemic lymphatics via paravertebral lymph nodes. Superficial and deep cervical lymph nodes collect CSF in mice, but the exact and quantified routes are unknown. Recently, we simultaneously visualized cervical, sacral and iliac lymph nodes via serial imaging on the intrathecal [64Cu]Cu‐albumin ...
Kyuwan Kim +11 more
wiley +1 more source
MetF is essential for both in vitro and in vivo growth of Mycobacterium tuberculosis, whereas MetE, previously considered essential in vitro, is dispensable in vivo. Given the importance of methionine and folate metabolism as drug targets, MetF represents a promising candidate, highlighting the need for in vivo validation.
Ikue Tosa +15 more
wiley +1 more source
Commentary: A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision
Xiaolong Liang, Mark Radosevich
doaj +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella +6 more
wiley +1 more source
Depletion of m6A-RNA in Escherichia coli reduces the infectious potential of T5 bacteriophage
N6-Methyladenosine (m6A) is the most abundant internal modification of mRNA in eukaryotes that plays, among other mechanisms, an essential role in virus replication.
Bibakhya Saikia +4 more
doaj +1 more source

