Results 71 to 80 of about 25,973 (199)

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Small, EarlyView.
A phage‐free, microbial platform produces programmable circular ssDNA libraries that are enzymatically converted into DNA origami staple pools. Rolling‐circle replication generates sequence‐complex ssDNA with >99% fidelity, enabling assembly of DNA tiles and tubules and supporting nanostructure formation even in crude cellular lysates.
Ming Hung Yen, Mallikarjuna Reddy Kesama, Yancheng Du, Jong Hyun Choi, Kevin V. Solomon   +4 more
wiley   +1 more source

Insights into the Functions of a Prophage Recombination Directionality Factor

Viruses, 2012
Recombination directionality factors (RDFs), or excisionases, are essential players of prophage excisive recombination. Despite the essentially catalytic role of the integrase in both integrative and excisive recombination, RDFs are required to direct ...
Mireille Ansaldi, Vincent Méjean, Gaël Panis, Nathalie Franche   +3 more
doaj   +1 more source

Characterization of the dynamic microbiome evolution across thrips species

Insect Science, EarlyView.
Comprehensive survey of the microbiome in thrips. The dominant bacterial genera found in thrips include intracellular ones, such as Wolbachia and Spiroplasma, and extracellular ones, including Serratia, Pantoea, and Acinetobacter. We isolated and sequenced high‐quality genomes of two dominant symbionts, Pantoea dispersa and Serratia marcescens.
Xiaodi Hu, Zhaohui Shi, Yangwei Gao, Hanze Zheng, Lin Lin, Jian‐Ping Chen, Yong Chen, Chuan‐Xi Zhang, Yiyuan Li   +8 more
wiley   +1 more source

Effect of the microbiome on pathogen susceptibility across four Drosophilidae species

Insect Science, EarlyView.
Four Drosophilidae species were used to investigate how variation in the host microbiome influences susceptibility to infection. Microbial composition and abundance differed among species and treatments. The effects of microbiome manipulation on host survival were both species‐ and pathogen‐specific.
Hongbo Sun, Ben Longdon, Ben Raymond
wiley   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

The FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu, Maximilian J. L. J. Fürst, Oscar P. Kuipers   +2 more
wiley   +1 more source

A Short Introduction to Bacteriophages

Trends in Peptide and Protein Sciences, 2016
First discovered in the 19th century, bacteriophages (phages) are bacterial viruses and the most widespread entities on earth. Phages have multiple important roles in maintaining the bacterial population, carbon cycling, bacterial pathogenicity, and ...
Ramin Mazaheri Nezhad Fard
doaj   +1 more source

UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis

The FEBS Journal, EarlyView.
UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh, Bruno Faivre, Sophie‐Carole Chobert, Martial Rey, Sophie S. Abby, Julie Michaud, Tuan‐Anh Dinh, Alexandre Chilin, Olivier Lerouxel, Marc Fontecave, Fabien Pierrel, Murielle Lombard, Ludovic Pelosi   +12 more
wiley   +1 more source

Lysogeny and Colicinogeny in Escherichia coli [PDF]

Journal of General Microbiology, 1961
SUMMARY: One hundred and eighty-three strains of Escherichia coli were examined for lysogeny and colicinogeny: 40.4 % were neither lysogenic nor colicinogenic; 31.1 % were only colicinogenic; 13.1% were only lysogenic; 15.2% were lysogenic and colicinogenic.
openaire   +2 more sources

Mechanisms of Antiphage Defense in Prokaryotes

Антибиотики и Химиотерапия
The globalization of the problem of the formation of bacterial strains poly- and pan-resistant to known antimicrobial drugs creates high risks in the healthcare sector.
А. D. Daudova, Yu. Z. Demina, R. O. Abdrakhmanova, G. R. Baeva, T. S. Rubalskaia, A. L. Yasenyavskaya, O. V. Rubalsky, M. A. Samotrueva   +7 more
doaj   +1 more source