Results 71 to 80 of about 43,690 (287)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

open access: yesAdvanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer   +5 more
wiley   +1 more source

Role of Lysogenic Phages in the Dissemination of Antibiotic Resistance Genes Applied in the Food Chain

open access: yesFoods
Bacteriophages, first discovered in 1915, have re-emerged as critical players in microbial ecosystems, particularly in food production. Their ability to lysogenize bacterial hosts raises concerns about their role in the horizontal transfer of antibiotic ...
Rafael Dorighello Cadamuro   +7 more
doaj   +1 more source

Spirochaetes as intestinal pathogens: Lessons from a Brachyspira genome [PDF]

open access: yes, 2009
Anaerobic spirochaetes of the genus Brachyspira have long been known as important gut pathogens of pigs, but increasingly they are recognised as causing disease in birds and other animal species, including human beings.
Hampson, D.J., Ahmed, N.
core   +3 more sources

Phenazine‐Based Synthetic Biology to Signal Between Cells and Electrodes

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Bioelectronic systems that enable seamless communication between electronic devices and living systems represent a transformative frontier in biotechnology. Among available methodologies, redox based signaling offers unique advantages due to its ubiquity in biology and compatibility with standard electrochemical equipment, expanding on ...
Eric VanArsdale   +8 more
wiley   +1 more source

A Novel Inducible Prophage from Burkholderia vietnamiensis G4 Is Widely Distributed across the Species and Has Lytic Activity against Pathogenic Burkholderia

open access: yesViruses, 2020
Burkholderia species have environmental, industrial and medical significance, and are important opportunistic pathogens in individuals with cystic fibrosis (CF).
Rebecca Weiser   +6 more
doaj   +1 more source

SVep1, a temperate phage of human oral commensal Streptococcus vestibularis

open access: yesFrontiers in Microbiology, 2023
IntroductionBacteriophages play a vital role in the human oral microbiome, yet their precise impact on bacterial physiology and microbial communities remains relatively understudied due to the limited isolation and characterization of oral phages.
Miaomiao Wu   +9 more
doaj   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu   +4 more
wiley   +1 more source

Phage-Encoded LuxR-Type Receptors Responsive to Host-Produced Bacterial Quorum-Sensing Autoinducers

open access: yesmBio, 2019
Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to orchestrate collective behaviors. QS relies on the cell-density-dependent production, accumulation, and receptor-mediated detection of extracellular signaling molecules ...
Justin E. Silpe, Bonnie L. Bassler
doaj   +1 more source

PhageLeads: Rapid Assessment of Phage Therapeutic Suitability Using an Ensemble Machine Learning Approach

open access: yesViruses, 2022
The characterization of therapeutic phage genomes plays a crucial role in the success rate of phage therapies. There are three checkpoints that need to be examined for the selection of phage candidates, namely, the presence of temperate markers ...
Kumarasan Yukgehnaish   +8 more
doaj   +1 more source

Lysogeny In Coagulase-Negative Staphylococci [PDF]

open access: yesJournal of Medical Microbiology, 1971
Summary Lysogenicity in coagulase-negative staphylococci was tested by incubating the strains in the presence of Mitomycin C. Among 173 strains examined, 45 were found to release phage. Twenty-eight of these phages were obtained from 90 strains belonging to Staphylococcus epidermidis biotype 1 (Baird-Parker, 1965).
J, Verhoef, K C, Winkler, C P, van Boven
openaire   +2 more sources

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