Results 141 to 150 of about 42,626 (246)

Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products

The FEBS Journal, Volume 293, Issue 5, Page 1341-1357, March 2026.
We have converted the only known true bacterial monoterpene synthase, cineole synthase from Streptomyces clavuligerus (bCinS, C10 substrate), to a highly competent sesquiterpene synthase (C15) with a minimum number of rational mutations. By comparison with diterpene synthases (C20), we were then able to bestow diterpene synthase activity on bCinS. This
Nicole G. H. Leferink, Joshua N. Whitehead, Linus O. Johannissen, Nigel S. Scrutton   +3 more
wiley   +1 more source

Crystal structure of plant γ‐glutamyl peptidase 1: implications for sulfur metabolism and secondary metabolite biosynthesis

The FEBS Journal, Volume 293, Issue 5, Page 1400-1414, March 2026.
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone, Takehiro Ito, Hibiki Sawada, Chihaya Yamada, Toma Kashima, Akimasa Miyanaga, Naoko Ohkama‐Ohtsu, Shinya Fushinobu   +7 more
wiley   +1 more source

Defender or accomplice? Dual roles of plant vesicle trafficking in restricting and enabling geminiviral systemic infection

New Phytologist, Volume 249, Issue 6, Page 2986-3002, March 2026.
Summary The vesicle trafficking system enables multidirectional cargo fluxes between endomembrane compartments. However, vesicle trafficking plays dual roles during pathogen infections. In plants, it mediates autophagic immune responses but can also be hijacked by pathogens to facilitate successful infections.
Pepe Cana‐Quijada, Pablo Morales‐Martínez, Tábata Rosas‐Díaz, Jessica Pérez‐Sancho, Tamara Jiménez‐Góngora, José Antonio Navarro, Rosa Lozano‐Durán, Araceli G. Castillo, Vicente Pallás, Eduardo R. Bejarano   +9 more
wiley   +1 more source

Causes and consequences of bacterial local adaptation via MGEs in the plant microbiome

New Phytologist, Volume 249, Issue 5, Page 2215-2223, March 2026.
Summary Adaptations that enable plant‐associated bacteria to fill disparate niches comprise a critical component of microbial diversity. Genes that confer locally adaptive bacterial traits, ranging from heavy metal resistance to pathogen or symbiont infectivity, often reside within mobile genetic elements (MGEs) that can move between genomes.
Stephanie Porter, Dominique Holtappels, Angeliqua Montoya, Britt Koskella   +3 more
wiley   +1 more source

Dual‐Role GH7 Family Proteins From Verticillium dahliae Function as Virulence Factors and Intracellular Effectors Triggering NLR‐Mediated Immunity

Plant, Cell &Environment, Volume 49, Issue 3, Page 1491-1504, March 2026.
ABSTRACT Cell wall–degrading enzymes are viewed as extracellular virulence factors. However, their potential to act as immune elicitors and interact with intracellular immune receptors remains poorly defined. Here, we demonstrate that six conserved glycoside hydrolase 7 (GH7) family proteins from the fungal pathogen Verticillium dahliae have dual roles
Xiao‐Bin Ji, Quan‐Le Zhang, Xin‐Xin Liu, Xia‐Yu Wang, Ya‐Duo Zhang, Xiao‐Feng Dai, Jin‐Long Wang, Krishna V. Subbarao, Dan‐Dan Zhang, Xiao‐Ping Hu, Jie‐Yin Chen   +10 more
wiley   +1 more source

Transcriptomic profiling of a commensal Escherichia coli lysogen in simulated intestinal fluid reveals broad changes in both core and accessory regions of the genome. [PDF]

BMC Genomics
Pick K, Raivio TL.
europepmc   +1 more source

Discovery and characterization of a novel <i>Pseudomonas</i> phage of a new genus. [PDF]

Phage (New Rochelle)
Nicholls P, Clark JR, Maresso A.
europepmc   +1 more source

Prophage border curation reveals horizontal transfer of lysogeny-related elements between filamentous and double jelly-roll phages. [PDF]

Commun Biol
Ma R, Zhang R.
europepmc   +1 more source

Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1-Like Repressor for Heterotypic Superinfection Immunity. [PDF]

J Basic Microbiol
Shafer N, Dubrule BE, De Buck J.
europepmc   +1 more source

Review of the Arbitrium (ARM) System: Molecular Mechanisms, Ecological Impacts, and Applications in Phage-Host Communication. [PDF]

Microorganisms
Shang J, Zhou Q, Wei Y.
europepmc   +1 more source