Results 161 to 170 of about 43,690 (287)

Maladaptive Inflammatory Signaling in Old Mice Impairs Colonic Regeneration by Promoting a Sustained Fetal‐Like Epithelial State

Aging Cell, Volume 25, Issue 5, May 2026.
This study explores the impact of aging on regeneration of the mouse colonic epithelium. The authors find that old mice exhibit excessive and prolonged inflammation after infection with Citrobacter, resulting in the maintenance of a fetal regenerative state in epithelial cells, insufficient tissue repair, and death of the animal.
Antonion Korcari, Helen Tauc, Jeff Duggan, Jina Yun, Fabien Wehbe, Spyros Darmanis, Zora Modrusan, Rajita Pappu, David Garfield, Heinrich Jasper, David Castillo‐Azofeifa   +10 more
wiley   +1 more source

Investigating the molecular mechanisms underlying the anti‐CRISPR function of AcrIIA13b protein

The FEBS Journal, Volume 293, Issue 9, Page 2560-2578, May 2026.
Anti‐CRISPR protein AcrIIA13b inhibits CRISPR–Cas9 function by preventing target DNA engagement. The Cas9–sgRNA ribonucleoprotein (RNP) normally recognizes the protospacer adjacent motif (PAM) duplex to initiate DNA cleavage. AcrIIA13b binding to the PAM‐interacting WED–PI domain blocks this recognition, leaving the target DNA intact.
So Yeon Lee, Hyun Ho Park
wiley   +1 more source

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

The FEBS Journal, Volume 293, Issue 9, Page 2772-2793, May 2026.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima, Dev Sriranganadane, Daiane Laise da Silva, Natália C. Drebes Dörr, Enzo Breviglieri Sichi Mello, Caio Vinicius dos Reis, Rogério Ferreira Lourenço, José Felipe Teixeira da Silva Santos, Anita Salmazo, Brenno Wendler Miranda, Katlin B. Massirer, Rafael M. Couñago, Cristina E. Alvarez‐Martinez   +12 more
wiley   +1 more source

Algal blooms as biofilm analogues: Evolutionary insights into cyanobacterial adaptation

Limnology and Oceanography Letters, Volume 11, Issue 3, May 2026.
Hidetoshi Urakawa, Hans W. Paerl
wiley   +1 more source

A Revised Understanding of Petalomonad Diversity (Petalomonadida; Euglenida) Enabled by a Cultivation Approach, With Five New Species and Two New Genera

Journal of Eukaryotic Microbiology, Volume 73, Issue 3, May/June 2026.
ABSTRACT Euglenids are an important group of free‐living phototrophic, osmotrophic, or phagotrophic protists, with most of the phylogenetic diversity represented by phagotrophs. One major subgroup of phagotrophs is the petalomonads: rigid, often relatively small cells with few pellicle strips (usually 4–8).
Won Je Lee, Gordon Lax, Elizabeth J. Weston, Julia A. Packer, Alexandra Hall, Sun Young Kim, Dong Hyuk Jeong, Alastair G. B. Simpson   +7 more
wiley   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

Journal of Gastroenterology and Hepatology, Volume 41, Issue 5, Page 1446-1458, May 2026.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen, Caihan Duan, Keyi Zhang, Jun Liu, Chaoqun Han   +4 more
wiley   +1 more source

A Fusarium sacchari Glycoside Hydrolase 12 Protein FsEG1 Is a Major Virulence Factor During Sugarcane Infection and Confers Resistance to Pokkah Boeng Disease via the HIGS Strategy

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3458-3478, May 2026.
ABSTRACT Pokkah Boeng disease (PBD), caused by Fusarium sacchari, has severely impacted the yield and quality of sugarcane, resulting in significant economic losses. However, the molecular interaction mechanisms between F. sacchari and sugarcane remain poorly understood.
Deng Wu, Tianshu Hong, Lulu Wang, Qianqian Ren, Shichao Wang, Yixue Bao, Muqing Zhang, Wei Yao, Qin Hu   +8 more
wiley   +1 more source

Viable but Nonculturable State, a Survival Strategy for Salmonella in Aquatic Environments

Water and Environment Journal, Volume 40, Issue 2, Page 183-202, May 2026.
Transition of Salmonella from a culturable state to a viable but nonculturable state under various environmental stresses and current methods for detecting viable Salmonella in environmental samples. ABSTRACT In the relentless battle for survival, Salmonella has evolved mechanisms to withstand harsh conditions such as extreme temperatures, fluctuating ...
Sanelisiwe Thinasonke Duze, Musa Marimani, Katlego Mamabolo, Mrudula Patel   +3 more
wiley   +1 more source

Characterization of the Human Blood Group Glycosyltransferases GTA and GTB for the Synthesis of Blood Group Antigens

Advanced Synthesis &Catalysis, Volume 368, Issue 8, 15 April 2026.
This study presents the highly efficient heterologous production of the human blood group glycosyltransferases GTA/R176A and GTB, along with their comprehensive biochemical and kinetic characterization. Tailored enzyme cascades, involving the bacterial fucosyltransferase FutC and GTA or GTB, generate milligram quantities of various blood group ABH ...
Katja Pöstges, Philip Palm, Kai P. Hussnaetter, Eliška Filipová, Helena Pelantová, Lucie Petrásková, Pavla Bojarová, Vladimír Křen, Lothar Elling   +8 more
wiley   +1 more source

Dual control of lysogeny and phage defense by a phosphorylation-based toxin/antitoxin system [PDF]

, 2022
Xiaoxue Wang, Yunxue Guo, Kaihao Tang, Brandon Sit, Jiayu Gu, Ran Chen, Jianzhong Lin, Shituan Lin, Xiaoxiao Liu, Weiquan Wang, Xinyu Gao, Zhaolong Nie, Tianlang Liu, Matthew K. Waldor   +13 more
openalex   +1 more source