Results 151 to 160 of about 43,690 (287)

The role of influenza neuraminidase transmembrane domain on budding and virus morphology [PDF]

open access: yes, 2014
Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in
Roddy, Scott, Edward
core  

Optimal 1TEL–target protein linker character is target protein‐dependent

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 516-532, May 2026.
In this study, we examine the effect of short to medium‐length flexible, semi‐flexible and rigid linkers on the crystallization of a DARPin or the TNK1 UBA domain fused to the 1TEL protein crystallization chaperone, demonstrating that while rigid linkers can impair crystallization and reduce diffraction quality, the ideal linker character remains ...
Maria J. Pedroza Romo   +22 more
wiley   +1 more source

Depletion of m6A-RNA in Escherichia coli reduces the infectious potential of T5 bacteriophage

open access: yesMicrobiology Spectrum
N6-Methyladenosine (m6A) is the most abundant internal modification of mRNA in eukaryotes that plays, among other mechanisms, an essential role in virus replication.
Bibakhya Saikia   +4 more
doaj   +1 more source

The Bacillus phage SPβ and its relatives: A temperate phage model system reveals new strains, species, prophage integration loci, conserved proteins and lysogeny management components [PDF]

open access: green, 2021
Katharina Kohm   +8 more
openalex   +1 more source

Mapping the effects of specific radiation damage and solvent radiolysis in buffers and crystals with online UV–Vis absorption spectroscopy

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 504-515, May 2026.
Radiation‐induced changes during X‐ray crystallographic data collection can compromise concurrent spectroscopic studies. Suitable protocols to detect and identify spectral artefacts from crystallization buffers and cryoprotectants are essential for the reliable analysis of chromophoric ligands in macromolecules.Online UV–Vis absorption spectroscopy is ...
Jack Stubbs   +8 more
wiley   +1 more source

Soybean Bradyrhizobium spp. Spontaneously Produce Abundant and Diverse Temperate Phages in Culture

open access: yesViruses
Soybean bradyrhizobia (Bradyrhizobium spp.) are symbiotic root-nodulating bacteria that fix atmospheric nitrogen for the host plant. The University of Delaware Bradyrhizobium Culture Collection (UDBCC; 353 accessions) was created to study the diversity ...
Vanessa A. Richards   +4 more
doaj   +1 more source

A Novel Small Molecule Accelerates Early Persister Regrowth and Potentiates Antibiotic Killing via MdtL–DcrB

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
bymBDZ accelerates early regrowth of persister‐derived E. coli and potentiates antibiotic killing. Its activity requires the MdtL–DcrB axis and is associated with envelope‐linked transport changes that increase intracellular small‐molecule exposure during recovery, thereby enhancing clearance in early treatment windows. ABSTRACT Persister cells survive
Garin Park, Hyein Kim, Sooyeon Song
wiley   +1 more source

Characterization of the Orphan Cytochrome P450 CYP107J1 From Bacillus subtilis Through Peroxygenase Activity Engineering

open access: yesMicrobial Biotechnology, Volume 19, Issue 5, May 2026.
The orphan cytochrome P450 CYP107J1 with unknown redox partners was rationally modified into H2O2‐driven form. The QE (E251Q/T252E) mutant produced valuable chemicals by simply mixing the enzyme with substrate and H2O2. ABSTRACT Cytochrome P450 monooxygenases (P450s) not only play many physiological roles in oxidative metabolism but are also promising ...
Hideki Kato   +5 more
wiley   +1 more source

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