Results 41 to 50 of about 42,626 (246)

Giant number fluctuations in microbial ecologies

, 2012
Statistical fluctuations in population sizes of microbes may be quite large depending on the nature of their underlying stochastic dynamics. For example, the variance of the population size of a microbe undergoing a pure birth process with unlimited ...
Das, Dibyendu, Das, Dipjyoti, Prasad, Ashok   +2 more
core   +1 more source

Lysogen stability is determined by the frequency of activity bursts from the fate‐determining gene

Molecular Systems Biology, 2010
The ability of living cells to maintain an inheritable memory of their gene‐expression state is key to cellular differentiation. Bacterial lysogeny serves as a simple paradigm for long‐term cellular memory.
Chenghang Zong, Lok‐hang So, Leonardo A Sepúlveda, Samuel O Skinner, Ido Golding   +4 more
doaj   +1 more source

Studies on Escherichia coli HflKC suggest the presence of an unidentified λ factor that influences the lysis-lysogeny switch

BMC Microbiology, 2011
Background The lysis-lysogeny decision in the temperate coliphage λ is influenced by a number of phage proteins (CII and CIII) as well as host factors, viz. Escherichia coli HflB, HflKC and HflD. Prominent among these are the transcription factor CII and
Parua Pabitra K, Bandyopadhyay Kaustav, Datta Ajit B, Parrack Pradeep   +3 more
doaj   +1 more source

Temporal Dynamics of Soil Virus and Bacterial Populations in Agricultural and Early Plant Successional Soils

Frontiers in Microbiology, 2020
As reported in many aquatic environments, recent studies in terrestrial ecosystems implicate a role for viruses in shaping the structure, function, and evolution of prokaryotic soil communities.
Krishnakali Roy, Dhritiman Ghosh, Jennifer M. DeBruyn, Tirthankar Dasgupta, K. Eric Wommack, Xiaolong Liang, Regan E. Wagner, Mark Radosevich   +7 more
doaj   +1 more source

Lysogeny destabilizes computationally simulated microbiomes

Ecology Letters, 2023
AbstractBackgroundThe Anna Karenina Principle predicts that stability in host-associated microbiomes correlates with health in the host. Microbiomes are ecosystems, and classical ecological theory suggests that predators impact ecosystem stability. Phages can act as predators on bacterial species in microbiomes.
R. Tucker Gilman, Mark R. Muldoon, Spyridon Megremis, David L. Robertson, Nina Chanishvili, Nikolaos G. Papadopoulos   +5 more
openaire   +3 more sources

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

mBio, 2020
Clostridioides difficile is an important nosocomial pathogen that causes approximately 500,000 cases of C. difficile infection (CDI) and 29,000 deaths annually in the United States.
Kurt Selle, Joshua R. Fletcher, Hannah Tuson, Daniel S. Schmitt, Lana McMillan, Gowrinarayani S. Vridhambal, Alissa J. Rivera, Stephanie A. Montgomery, Louis-Charles Fortier, Rodolphe Barrangou, Casey M. Theriot, David G. Ousterout   +11 more
doaj   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source

Lysogeny In Coagulase-Negative Staphylococci [PDF]

Journal of Medical Microbiology, 1971
Summary Lysogenicity in coagulase-negative staphylococci was tested by incubating the strains in the presence of Mitomycin C. Among 173 strains examined, 45 were found to release phage. Twenty-eight of these phages were obtained from 90 strains belonging to Staphylococcus epidermidis biotype 1 (Baird-Parker, 1965).
J, Verhoef, K C, Winkler, C P, van Boven
openaire   +2 more sources