Results 131 to 140 of about 32,338 (252)

Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi, Federica Martina Di Domenico, Gian Marco Leggio, Giuseppe Caruso, Evelyn Frias‐Toral, Nohora Milena Martínez López, Agnieszka Micek, Marialaura Bonaccio, Justyna Godos, Giuseppe Grosso   +9 more
wiley   +1 more source

Effect of quercetin and its metabolite on caveolin-1 expression induced by oxidized LDL and lysophosphatidylcholine in endothelial cells [PDF]

, 2016
Oxidized low-density lipoprotein contributes to atherosclerotic plaque formation, and quercetin is expected to exert anti-atherosclerotic effects. We previously reported accumulation of conjugated quercetin metabolites in the aorta of rabbits fed high ...
Sato, Shinya, 10955/profile-ja.html, 170, 90547978, 寺尾, 純二, 60093275, ムカイ, リエ, 203812/profile-ja.html, Mukai, Rie, 向井, 理恵, Kondo, Akari, 鎌田, 智英実, 410, サトウ, シンヤ, カマダ, チエミ, テラオ, ジュンジ, Kamada, Chiemi, コンドウ, アカリ, Terao, Junji   +18 more
core  

Impacts of M. oleifera Leaf Extract on Weight Loss, the Metabolomic Profile, and the Intestinal Microbiota in Individuals With Simple Obesity

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
A total of 63 subjects participated in the formal trial, randomly assigned to either the control group (n = 29) or the intervention group (n = 34). The trial period lasted 90 days, during which the intervention group consumed Moringa oleifera leaf extract while the control group received a corresponding placebo.
Xiaoxian Zhou, Daoqiang He, Jia Xiong, Xinle Zhang, Yongfang Zhou, Jia Luo, Lan Zhou, Huilin Chen, Jingwen Dao, Fei Mi, Yanjiao Wang, Shaoxiong Wu, Hongmei Pan   +12 more
wiley   +1 more source

Broccoli Sprout Extract Restores Renal Lipid Metabolism in High‐Fat Diet‐Fed Mice Involving Modulation of AMPK/Nrf2 Signaling and the NLRP3 Inflammasome

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
High‐fat diet (HFD) induces renal lipid accumulation, AMPK suppression, oxidative stress, and NLRP3 inflammasome activation, leading to renal injury. Broccoli sprout extract (BSE) concurrently activates AMPK signaling (promoting fatty acid oxidation and inhibiting lipogenesis), enhances Nrf2‐mediated antioxidant defense, and suppresses NLRP3‐driven ...
Chunting Wu, Bangzhao Zeng, Xuexun Li, Xin Zhao, Junyu Ma, Mengxue Zhang, Shuangshuang Zhao, Chunmei Zhang, Qin Gao, Fuli Ya   +9 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Possible Involvement of Lysophospholipids in Severe Asthma as Novel Lipid Mediators

Biomolecules
In severe asthma, symptoms are unstable despite intensive treatment based on high doses of inhaled corticosteroids and on-demand use of oral corticosteroids.
Hiroaki Kume, Kentaro Kazama, Riko Sato, Yuki Sato   +3 more
doaj   +1 more source

Lysophosphatidylcholine synthesis with Candida antarctica lipase B (Novozym 435)

, 2000
Immobilized lipase from Candida antarctica lipase B (Novozym 435) was effective in the synthesis of lysophosphatidylcholine (LPC). The transesterification of L-α-glycerophosphorylcholine (GPC) and vinyl laurate was carried out in a solvent free system or
Carmen Virto, Adlercreutz, Patrick, Virto, Carmen, Patrick Adlercreutz   +3 more
core   +1 more source

Systematic Analysis of Plasma‐Derived Extracellular Vesicle‐Enriched Samples in Age‐Related Macular Degeneration Reveals Oxidative Stress Linked to Altered Lipid and Protein Profiles

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Vision impairment caused by age‐related macular degeneration (AMD) is a global health priority. Retinal pathology is driven by ageing and exacerbated by genetic and environmental risk factors. Peripheral blood circulation is increasingly recognised as a contributor to disease initiation and progression, and a source of biomarkers to support ...
Marzena Kurzawa‐Akanbi, Jennifer Haggarty, Carina Hansohn, Mohamed T. Patel, Angela J. Cree, Peisi Teo, Milly Armstrong, Nathan Coles, Mark Platt, Helen Griffiths, Heather J. Cordell, Ahmad Khundakar, Pola Goldberg Oppenheimer, Phillip Whitfield, Andrew Lotery, Henning Urlaub, Sina Mozaffari‐Jovin, Majlinda Lako   +17 more
wiley   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source