Results 121 to 130 of about 32,338 (252)

Preparation, characterization and bioavailability by oral administration of O/W curcumin nanoemulsions stabilized with lysophosphatidylcholine

, 2017
Curcumin has low solubility in aqueous media. In our study, O/W nanoemulsions of curcumin were prepared using lysophosphatidylcholine, to increase its bioavailability when administered orally.
Rubi Chávez-Zamudio, Angélica A. Ochoa-Flores, Ida Soto-Rodríguez, Hugo Sergio García, Rebeca Garcia-Varela   +4 more
core   +1 more source

The High‐Sensitivity C‐Reactive Protein−Albumin−Lymphocyte Index Is a Prognostic Marker for All‐Cause and Cardiovascular Mortality in Patients With ST‐Elevation Myocardial Infarction

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 1034-1046, September 1, 2026.
ABSTRACT Background Inflammation and immune dysfunction may worsen the prognosis of patients with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess whether the high‐sensitivity C‐reactive protein–albumin–lymphocyte index (hsCALLYI) could be used to predict the prognosis of STEMI patients who received emergency ...
Xinuo Ma, Wei Zhang, Ningli Zhang, Qinghua Zhong, Tao Shi, Sirui Yang, Fazhi Yang, Yujuan Peng, Lixing Chen   +8 more
wiley   +1 more source

Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review systematically examines the role of gut microbiota modulation in Alzheimer's disease, focusing on how microbial metabolites and dietary nutrients influence cognitive function and AD pathology, as well as the neuroprotective effects through the gut‐brain axis.
Binyue Xu, Xuhuan Li, Shangling Dong, Zheyuan Zhang, Dong Jin, Guoping Li, Jiesheng Wang   +6 more
wiley   +1 more source

Advances in Targeting Central Cholinergic Dysfunction for Neurodegenerative Diseases: From Pharmacotherapy to Neuromodulation

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review charts the evolution of cholinergic therapies for neurodegenerative diseases—from classical acetylcholinesterase inhibitors (AChEIs) providing symptomatic relief to precision multi‐target drugs and neuromodulation (VNS, DBS, NIBS) that restore dysfunctional circuits. Emerging gene therapy, cell regeneration, and advanced cholinergic imaging
Lei Lei, Xiaoyu Hu, Ruida Lu, Jian‐jun Yang, Qingsheng Meng   +4 more
wiley   +1 more source

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen, Wangzheqi Zhang, Lizhou Song, Yan Liao, Haoling Zhang, Yiyang Xia, Derong Cui   +6 more
wiley   +1 more source

Metabolomic Profiling Delineates Stage‐Associated Metabolic Remodelling in Cardiovascular‐Kidney‐Metabolic Syndrome

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
Using widely targeted metabolomics, we profiled 1374 participants across CKM stages 0–4 and identified 261 metabolites exhibiting distinct, non‐linear patterns of remodelling in lipid, carbohydrate, amino acid, and redox/energy metabolism. WGCNA further identified a 148‐metabolite turquoise module associated with CKM stage, with γ‐glutamylvaline ...
Xuemei Gong, Chunyang Li, Jing Chen, Yujiao Wang, Wenge Tang, Xuehui Zhang, Jianzhong Yin, Xing Zhao, Haopeng Yu, Ping Fu, Xiaoxi Zeng   +10 more
wiley   +1 more source

Differential levels of L-homocysteic acid and lysophosphatidylcholine (16:0) in sera of patients with ovarian cancer

, 2019
Biomarker; Cancer screening; L-homocysteic acid; Lysophosphatidylcholine (16:0); Ovarian ...
김승철, 김윤환, 이준화
core   +1 more source

Metabolite Signatures in Postpartum Prediabetes and Diabetes Among Indian Women With Prior Gestational Diabetes Mellitus: Insights From CHIP‐F Study

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
Metabolite Signatures in Postpartum Prediabetes and Diabetes Among Indian Women With Prior Gestational Diabetes Mellitus: Insights From CHIP‐F Study. ABSTRACT Aims Gestational diabetes mellitus (GDM) increases the risk of postpartum dysglycaemia. This study investigates candidate metabolites and perturbed metabolic pathways associated with postpartum ...
Sahil Kapoor, Ambika Singh, Neelam Mahlawat, J. Manivannan, Arpita Singh, Shinjini Bhatnagar, Nikhil Tandon, Yashdeep Gupta, Pallavi Kshetrapal   +8 more
wiley   +1 more source

Lysophosphatidylcholin [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Synthesis of Novel Lysophosphatidylcholine Analogues Using Serine as Chiral Template

, 2016
Four novel lysophosphatidylcholine (lysoPC) analogues, (S)-N-stearoyl-O-phosphocholineserine methyl ester [(S)-1a], (R)-1-lyso-2-stearoylamino-2-deoxy-sn-glycero-3-phosphatidylcholine [(R)-2a], (R)-N-stearoyl-O-phosphocholineserine methyl ester [(R)-1b],
Young-Ah Kim (2728225), Hae-Mi Chung (2728216), Ki-Hwan Kim (2728222), Juyoung Min (2728213), So-Yeop Han (2202817), Gil-Ja Jhon (2146687), Wonja Choi (2728231), Nok-Hyun Park (2728228), Jin-Seon Park (2728219)   +8 more
core   +1 more source