Results 141 to 150 of about 32,338 (252)

Ferroptosis: Newly Emerged Regulator for Human Disease

MedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao, Lin Ye, Tianqi Jiang, Mengyuan Liu, Yuxia Zhou   +4 more
wiley   +1 more source

Dietary Intervention With Lutein, Docosahexaenoic Acid, and Choline During Early Development Improves Recognition Memory in Young Adult Females in an Experimental Model

Molecular Nutrition &Food Research, Volume 70, Issue 17, 15 September 2026.
Our study investigates the effects of perinatal supplementation with lutein, DHA, and choline in a controlled rat model. The results show: (1) strictly sex‐specific effects exclusively observed in female rats, (2) lutein‐dependent and synergistic effects, (3) enhancement of long‐term recognition memory, and (4) no effects on locomotor activity, anxiety‐
Leon Saschin, Gregor Fink, Maria Wohlfarth, Jonas Hauser, Jian Yan, Dirk Wiedermann, Mathias Hoehn, Jochen Wilhelm, Lea Quell, Elisabeth Sous, Jenny Voggel, Jörg Dötsch, Eva Nüsken, Kai‐Dietrich Nüsken   +13 more
wiley   +1 more source

Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes

, 2012
Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 ...
Margaret Staples (149072), Melissa N Barber (13708222), Christine Yang (149071), Clinton Bruce (13064589), Peter J Meikle (9630077), Mark A Febbraio (12274028), Steve Risis (149069)   +6 more
core  

Urotensin II Receptor Deletion Mitigates Kidney Injury and Renal Lipid Remodeling in Mice Fed a Long‐Term High‐Fat Diet

FASEB BioAdvances, Volume 8, Issue 9, September 2026.
Urotensin II receptor deletion mitigates high‐fat diet‐induced kidney injury and renal lipid remodeling. Male wild‐type (WT) and urotensin II receptor–knockout (UT KO) mice were fed a high‐fat diet (HFD; 60% kcal from fat) for 33 weeks. In cultured mouse podocytes, urotensin II (UII)–UT signaling enhanced transient receptor potential canonical 6 (TRPC6)
Praghalathan Kanthakumar, Adebowale Adebiyi   +1 more
wiley   +1 more source

Effects of lysophosphatidylcholine on growth performance， serum biochemical indicators， liver morphology， and intestinal health in Micropterus salmoides fed low-fat diet

Siliao yanjiu
The experiment aimed to investigate the effects of dietary supplementation with lysophosphatidylcholine (LPC) in low-fat diets on the growth performance, serum biochemical indicators, liver morphology, and intestinal health of Micropterus salmoides.
WEI Yuqiang, LIU Xiaochuan, BI Yulin, ZHAO Jianguo, ZHOU Zhihao, XU Qiyou   +5 more
doaj  

Metabolic Profiling of Epigenetic Aging and Its Associations With Aging‐Related Phenotypes and Modifiable Lifestyle Factors

Aging Cell, Volume 25, Issue 9, September 2026.
This study provides novel insights into the metabolic correlates of epigenetic aging biomarkers and underscores the potential of metabolomics‐informed metrics of epigenetic aging as informative indicators of physiological decline and lifestyle effects.
Xunying Zhao, Tianpei Ma, Maoyao Xia, Xinyang Dui, Yangdan Zhong, Xin Chen, Yang Qu, Bowen Lei, Qingwen Zhao, Xueyao Wu, Haiyu Yan, Xingyu Zhang, Ke Jiang, Lin Hu, Lu Long, Mengyu Fan, Jiaqiang Liao, Tao Zhang, Xia Jiang, Jiayuan Li, Ben Zhang   +20 more
wiley   +1 more source

Molecular Mediators Associated With Myelination, Demyelination, and Remyelination in the Peripheral Nervous System

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT The peripheral nervous system (PNS) is responsible for innervating all regions of the body outside of the central nervous system (CNS), the latter consisting of the brain, spinal cord, and optic nerves. While myelin is an essential component for the efficient functioning of both CNS and peripheral nerve cells, it is particularly important for ...
Kathleen Margaret Hagen, Shalina Sheryl Ousman   +1 more
wiley   +1 more source

Cucumber Mosaic Virus Promotes Sphingolipid Biosynthesis to Alleviate Host Unfolded Protein Response (UPR)‐Mediated Immunity

Molecular Plant Pathology, Volume 27, Issue 9, September 2026.
Sphingolipid levels are elevated in CMV replication site (the tonoplast). Silencing Nb‐TSC10 activates the host salicylic acid–UPR defence axis, indicating CMV promotes sphingolipid biosynthesis to suppress this antiviral pathway. ABSTRACT RNA viruses usually reprogramme host cellular lipid metabolism to create favourable replication microenvironments,
Jiayi Yao, Shaomin Wu, Shushu Gao, Zhidan Xiang, Qian Wang, Fei Ye, Qiansheng Liao, Zhouhang Gu, Zhiyou Du   +8 more
wiley   +1 more source

Impact of aging on neck vasculature and brain biochemistry in female mice

Physiological Reports, Volume 14, Issue 17, September 2026.
Abstract Age‐related changes in large‐vessel biomechanics may contribute to neurovascular dysfunction and region‐specific biochemical remodeling in the brain, with important implications for female health. This study investigated the impact of aging on neck vasculature and brain lipid biochemistry in female C57BL/6NHsd mice by comparing young (12 weeks;
Allison R. Jones, Amin Jarrahi, Kylee Karpowich, EllaGrey Moody, Lily Renner, Lindsay P. Brown, Caitlin M. Tressler, A. Colleen Crouch   +7 more
wiley   +1 more source

Predictive Value of Lysophosphatidylcholine for Determining the Disease Severity and Prognosis of Elderly Patients with Community-Acquired Pneumonia

Clinical Interventions in Aging
Minghao Gu,1,2 SenSen Lv,1 Yihui Song,3 Hong Wang,4 Xingyu Zhang,5 Jing Liu,1 Deshun Liu,1 Xiudi Han,1 Xuedong Liu1 1Department of Respiratory and Critical Care Medicine, Qingdao Municipal Hospital, Qingdao, 266011, People’s Republic of China; 2School of
Gu M, Lv S, Song Y, Wang H, Zhang X, Liu J, Liu D, Han X, Liu X   +8 more
doaj