Results 121 to 130 of about 7,434 (235)

Lung surface-active fraction as a model system for macromolecular ultrastructural studies with Crotalus atrox venom

Journal of Lipid Research, 1973
The dog lung surface-active fraction and phosphatidylcholine constituents were subjected to hydrolysis by Crotalus atrox phospholipase A2. Relative rates of hydrolysis were: dipalmitoyl glycerophosphorylcholine > phosphatidylcholine isolated from the ...
M.F. Frosolono, R. Pawlowski, B.L. Charms, C. Corbusier, M. Abrams, J. Jones, III   +5 more
doaj   +1 more source

Elevated Gestational IL-13 During Fetal Development Is Associated With Hyperactivity and Inattention in Eight-Year-Old Children [PDF]

, 2019
Maternal immune activation (MIA) during fetal development leads to behavioral and psychological disorders in the offspring. Concomitantly, insufficient supply of polyunsaturated fatty acids (PUFAs) is suspected to contribute to early neuronal ...
Bergen, Martin von, Borte, Michael, Herberth, Gunda, Lehmann, Irina, Rolle-Kampczyk, Ulrike, Röder, Stefan, Thürmann, Loreen, Trump, Saskia   +7 more
core   +1 more source

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

Photochemistry and Photobiology, EarlyView.
Verteporfin's subcellular localization governs its ability to deplete ATP. LysoPC‐conjugated VP accumulates in lysosomes and spares mitochondria, while liposomal and NanoVP formulations target mitochondria, where light activation triggers membrane depolarization and ATP depletion, overcoming resistance seen with free‐form VP. Abstract P‐glycoprotein (P‐
Idrisa Rahman, Anju Meda, Kaitlyn A. Moore, Payal Srivastava, Anika Dasgupta, Andaleeb Sajid, Suresh V. Ambudkar, Huang‐Chiao Huang   +7 more
wiley   +1 more source

Proteomic and metabonomic biomarkers for hepatocellular carcinoma: a comprehensive review [PDF]

, 2014
Hepatocellular carcinoma (HCC) ranks third in overall global cancer-related mortality. Symptomatic presentation often means advanced disease where potentially curative treatment options become very limited.
Fye, H, Holmes, E, Kimhofer, T, Taylor-Robinson, S, Thursz, M   +4 more
core   +2 more sources

Longitudinal metabolomics study of phosphate‐adenine‐guanosine‐glucose‐saline‐mannitol stored red blood cells

Transfusion, EarlyView.
Abstract Background The storage of red blood cells (RBCs) is essential for transfusion but leads to storage lesions that compromise RBC quality and increase the risk of transfusion‐related adverse effects, including allergic transfusion reactions (ATRs). Understanding storage‐induced metabolic change is crucial for enhancing transfusion safety.
Gürkan Bal, Maia Dzamashvili, Zhuoran Li, Magda Babina, Nidal Toman, Abdulgabar Salama   +5 more
wiley   +1 more source

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations [PDF]

, 2011
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling.
A Cecile J W Janssens, Aaron Isaacs, Alan F Wright, Albert Hofman, Anatoly V Kirichenko, Andre Uitterlinden, Andrew A Hicks, Arne Pfeufer, Ayşe Demirkan, Ben A Oostra, CARDIoGRAM Consortium, Caroline Hayward, Carsten Gnewuch, CHARGE Consortium, Christopher J O'Donnell, Christopher P Nelson, Christopher S Franklin, Cornelia M van Duijn, Cristian Pattaro, DIAGRAM Consortium, EUROSPAN consortium, Fernando Rivadeneira, Francisco S Domingues, Gerd Schmitz, Gerhard Liebisch, Ghazal Zaboli, Harry Campbell, Igor Rudan, Inger Jonasson, Irene Pichler, Irina V Zorkoltseva, Ivana Kolcic, Jacqueline C M Witteman, James F Wilson, James Floyd, Jennifer Huffman, Joshua C Bis, Lennart C Karssen, Linda Broer, Lude Franke, Maksim Struchalin, Michael Preuss, Nicholas D Hastie, Nora Franceschini, Ozren Polasek, Peter P Pramstaller, Peter Ugocsai, Ritsert C Jansen, Sarah H Wild, Susan Campbell, Tatiana Axenovich, Thomas Meitinger, Ulf Gyllensten, Veronique Vitart, Wilmar Igl, Yurii S Aulchenko, Zrinka Biloglav, Åsa Johansson   +57 more
core   +13 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Gut Microbiota–Metabolism Axis Shapes the Individual Metabolic Phenotype of Different Microbiota‐Accessible Carbohydrates

Food Frontiers, Volume 7, Issue 2, March 2026.
Specific MAC bioactivities are associated with gut biotransformation. ABSTRACT Increasing the intake of microbiota‐accessible carbohydrates (MACs) has emerged as a promising nutritional strategy for preventing metabolic diseases. However, the consistency of their beneficial effects remains unclear, hindering their optimized application.
Na‐Na Zhang, Guo‐Quan Shao, Xin‐Xin Guo, Jing‐Yi Zhang, Yang Li, Li‐Li Wang, Yue Zhang, Feng‐Zhong Wang, Li‐Tao Tong   +8 more
wiley   +1 more source

Mechanism of Alfalfa in Enhancing Goose Egg Yolk Flavor: An Analysis Based on Metabolomics and Quantitative Lipidomics

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Organic egg production requires daily provision of coarse feed, fresh or dried forage, and silage to poultry. This study employed flavoromics, metabolomics, and quantitative lipidomics to investigate the effects of replacing 0% (CK), 10% (T10), and 20% (T20) of the basal diet of laying geese with alfalfa (Medicago sativa L.) on the sensory ...
Baochao Bai, Rui Qiu, Gentu Ge, Mingjian Liu, Yichao Liu, Muqier Zhao, Weiqin Ma, Panjie Sheng, Yushan Jia, Zhijun Wang   +9 more
wiley   +1 more source

Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination

Glia, Volume 74, Issue 3, March 2026.
Cuprizone demyelination induces transient reactive states in deep cortical microglia (MG) through early recovery. Depleting MG in recovery increases the number of deep cortical mature/pre‐myelinating oligodendrocytes. Deep cortical reactive MG reduce oligodendrocyte density after demyelination.
Hannah Katherine Loo, Joseph Gallegos, Christine Mialki, Gregory E. Perrin, Thomas Malloy, Jennifer L. Orthmann‐Murphy   +5 more
wiley   +1 more source