Results 101 to 110 of about 6,447 (173)

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, Volume 111, Issue 10, Page 4457-4497, 1 October 2026.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Transcriptomic and Metabolomic Profiling Identifies a Core Gene–Metabolite Axis Driving African Swine Fever Virus Replication in the Soft Tick Ornithodoros lahorensis

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Transcriptomic and metabolomic profiling of Ornithodoros lahorensis during African swine fever virus (ASFV) infection reveals that ASFV rewires host purine/pyrimidine metabolism, lipid metabolism, and energy metabolism. A core gene‐metabolite regulatory axis consisting of 12 key genes and 8 signature metabolites is identified to support viral genome ...
Jin Luo, Kaifei Guo, Fangyu Xiao, Ruoqi Wang, Junhui Guo, Qiaoyun Ren, Shuaiyang Zhao, Muhammad Kashif Obaid, Guiquan Guan, Hong Yin   +9 more
wiley   +1 more source

A Novel Strategy for Targeted Lipidomics Based on LC-Tandem-MS Parameters Prediction, Quantification, and Multiple Statistical Data Mining: Evaluation of Lysophosphatidylcholines as Potential Cancer Biomarkers

, 2019
Lipid quantification is the ultimate goal in lipidomics studies challenged by the availability of standard compounds. A novel strategy for targeted lipidomics based on LC-MS/MS parameters prediction and multivariate statistical analysis was developed for
Peng Gao, Ran Liu (303585), Wei Jin, Xiao Yang (19898), Qing Li (84975), Yiwen Zhang (512835), Yiwen Zhang, Huarong Xu (424596), Qing Li, Kaishun Bi, Kaishun Bi (429547), Peng Gao (35465), Ran Liu, Xiao Yang, Qian Zhang, Wei Jin (87150), Huarong Xu, Qian Zhang (49333)   +17 more
core   +1 more source

Lysophosphatidylcholines activate G2A inducing Gαi-1-/Gαq/11- Ca2+ flux, Gβγ-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs

, 2010
Lyso-PCs (lysophosphatidylcholines) are a mixture of lipids that accumulate during storage of cellular blood components, have been implicated in TRALI (transfusion-related acute lung injury) and directly affect the physiology of neutrophils [PMNs ...
Fabia Gamboni-Robertson, Christopher C. Silliman, Samina Y. Khan, Marguerite R. Kelher, Nathan J. D. McLaughlin, Phillip Eckels, Anirban Banerjee   +6 more
core   +1 more source

Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous quantification of mammal lysophosphatidylcholines and lysophosphatidylethanolamines in serum

, 2017
Filiació URV: SI URL: http://www.sciencedirect.com/science/article/pii/S1570023217303082Recent investigations based on non-targeted metabolomics have proposed lysophospholipids (Lyso-PLs) as biomarkers of different diseases.
Suárez-García, S.; Arola, L.; Pascual-Serrano, A.; Arola-Arnal, A.; Aragonès, G.; Bladé, C.; Suárez, M.
core   +1 more source

HPLC-MS-Based Metabonomics Reveals Disordered Lipid Metabolism in Patients with Metabolic Syndrome

Journal of Analytical Science and Technology, 2011
Ultra-high performance liquid chromatography/ quadrupole time of flight mass spectrometry-based metabonomics platform was employed to profile the plasma metabolites of patients with metabolic syndrome and the healthy controls. Data analysis revealed lots
Xinjie Zhao, Yan Chu, Shili Chen, Peng Gao, Li Zhang, Libin Zhan, Guowang Xu   +6 more
doaj  

Methods for joint modeling of longitudinal omics data and time-to-event outcomes: Applications to lysophosphatidylcholines in connection to aging and mortality in the Long Life Family Study

Studying the relationships between longitudinal changes in omics variables and event risks requires specific methodologies for joint analyses of longitudinal and time-to-event outcomes.
Gu, Yian, Arbeev, Konstantin G, Stallard, Eric, Schwaiger-Haber, Michaela, Kulminski, Alexander, Bagley, Olivia, Ukraintseva, Svetlana V, Patti, Gary J, Yashin, Anatoliy I, Province, Michael A   +9 more
core   +1 more source

血浆中溶血卵磷脂的轮廓分析：肺癌中生物标记物的发现及异构体的鉴定

, 2009
Lysophosphatidylcholines (lysoPCs) are a class of special structure endogenous compounds, which have the same polar head with different fatty acyls in chain lengths, fatty acyl position, degrees of saturation and different double bond location(s).
邹丽娟, 董军, 梁鑫淼, 蔡晓明, 张秀莉, 薛兴亚   +5 more
core  

Serum metabonomics study of chronic renal failure by ultra performance liquid chromatography coupled with Q-TOF mass spectrometry

, 2008
A metabonomics technique based on ultra-performance liquid chromatography (UPLC) coupled with Q-TOF mass spectrometry was employed to investigate the sera from 32 patients with chronic renal failure (CRF) without renal replacement therapy and 30 healthy ...
许国旺, Yin, Peiyuan, Jia, Lewen, Lu, Xin, Chen, Jing, Xu, Guowang   +5 more
core   +1 more source

Plasma lipidomics of tuberculosis patients: altered phosphatidylcholine remodeling

, 2018
Aim: Decreased circulating levels of lysophosphatidylcholines have been monitored in the serum of tuberculosis (TB) patients. However, the etiology of these findings has not been explored and other critical lung surfactant lipids have not been examined.
Soumya Tippireddy, Joshua Feriante, Paul L Wood   +2 more
core   +1 more source