Results 221 to 230 of about 231,658 (339)

NoxO1 promotes endosome formation and reduces intracellular vesicle processing. [PDF]

Redox Biol
Hebchen M, Herwig F, Schader T, Spaeth M, Müller N, Schröder K.   +5 more
europepmc   +1 more source

Processing of mitochondrial precursor proteins [PDF]

, 1984
Neupert, Walter, Schmidt, Bernd
core  

The significance of targeting lysosomes in cancer immunotherapy [PDF]

Yanxin Xu, Bo Shao, Yafeng Zhang
openalex   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Caveolin-1 Regulates Ultrastructural Alterations of Astrocytes in Chronic Cerebral Hypoperfusion. [PDF]

Inflammation
Wu M, Zhang X, Wang D, Shu X, Chen D, Zhao Y, Lv Q, Li Y, Huang Z, Gao J, Zhu W, Wang Z, Liu X, Xie Y.   +13 more
europepmc   +1 more source

INVOLVEMENT OF LYSOSOMES IN SPONTANEOUS ATHEROGENESIS AND THE EFFECTS OF ESTROGENS

, 1981
Jane L. Hough
openalex   +1 more source

The Presence of A manganese‐rich particle in lysosome of rat pancreas due to excess manganese treatment [PDF]

, 1997
Yoshihiro Okamoto, Reiko Oshima, Kazuhiro Inagaki, Saburo Aita, Hideo Nisioka, Yumi Kondo, Hiroshi Ishizuka, J. Takada, Mikio Nishida   +8 more
openalex   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

Maintenance and Decline of Neuronal Lysosomal Function in Aging. [PDF]

Cells
Zhong R, Richardson CE.
europepmc   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source