Results 251 to 260 of about 174,460 (337)

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu   +7 more
wiley   +1 more source

Degradation of Melanosomes by Lysosomes

open access: bronze, 1971
Noriko Ohtaki, Makoto Seiji
openalex   +1 more source

Transcription factor EB activation rescues advanced αB-crystallin mutation-induced cardiomyopathy by normalizing desmin localization [PDF]

open access: yes, 2019
Benjamin, Ivor J   +12 more
core   +1 more source

KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion

open access: yesAdvanced Science, EarlyView.
Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li   +12 more
wiley   +1 more source

Lysosomal PIP<sub>3</sub> revealed by genetically encoded lipid biosensors. [PDF]

open access: yesProc Natl Acad Sci U S A
Sahan AZ   +5 more
europepmc   +1 more source

Engineering Liquid Hierarchical Materials with DNA‐Programmed Spherical Nucleic Acids

open access: yesAdvanced Science, EarlyView.
Programmable spherical nucleic acids assembly strategies for constructing hierarchical structures through engineered DNA bond to form novel liquid‐like metal droplets. Abstract Inspired by nature, the orchestration of self‐assembling building blocks into hierarchical superstructures offers a transformative approach to functional materials design. While 
Zeyu Chen   +7 more
wiley   +1 more source

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