Results 251 to 260 of about 174,460 (337)

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

Advanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu, Xu Zhao, Yong Li, Xiaoya Ma, Weifeng Yang, Jie Ma, Wanglin Li, Wei Yuan   +7 more
wiley   +1 more source

Lysosome-associated CASM: from upstream triggers to downstream effector mechanisms. [PDF]

Front Cell Dev Biol
Kaur N, Carlsson SR, Lystad AH.
europepmc   +1 more source

Degradation of Melanosomes by Lysosomes

, 1971
Noriko Ohtaki, Makoto Seiji
openalex   +1 more source

Transcription factor EB activation rescues advanced αB-crystallin mutation-induced cardiomyopathy by normalizing desmin localization [PDF]

, 2019
Benjamin, Ivor J, Diwan, Abhinav, Foroughi, Layla, French, Brent A, Hill, Joseph A, Javeheri, Ali, Kovacs, Attila, Kraja, Aldi, Liu, Haiyan, Ma, Xiucui, Mani, Kartik, Murphy, John T, Weinheimer, Carla J   +12 more
core   +1 more source

KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion

Advanced Science, EarlyView.
Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li, Xuexin Yu, Yuanji Liu, Shuqin Ouyang, Long Wu, Xiaohong Chen, Huiqi Yu, Haoming Chen, Senmao Lian, Ziwen Li, Liyun Gong, Libing Song, Jun Li   +12 more
wiley   +1 more source

Lysosomal PIP₃ revealed by genetically encoded lipid biosensors. [PDF]

Proc Natl Acad Sci U S A
Sahan AZ, Chen M, Su Q, Li Q, Wang D, Zhang J.   +5 more
europepmc   +1 more source

Engineering Liquid Hierarchical Materials with DNA‐Programmed Spherical Nucleic Acids

Advanced Science, EarlyView.
Programmable spherical nucleic acids assembly strategies for constructing hierarchical structures through engineered DNA bond to form novel liquid‐like metal droplets. Abstract Inspired by nature, the orchestration of self‐assembling building blocks into hierarchical superstructures offers a transformative approach to functional materials design. While 
Zeyu Chen, Xu Chen, Dan Lu, Huating Kong, Jingyi Ye, Chunhai Fan, Honglu Zhang, Huan Zhang   +7 more
wiley   +1 more source

Transcriptional repression of autophagy and lysosome biogenesis. [PDF]

Autophagy
Kim J, Yu YS, Kim KI, Baek SH.
europepmc   +1 more source

Turnover of murine beta-glucuronidase. Comparison among liver, kidney, and spleen and between lysosomes and microsomes

, 1978
Kathy Beckingham Smith, R E Ganschow
openalex   +1 more source