Results 151 to 160 of about 239,873 (360)
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor [PDF]
, 2020 Amy H. Ponsford +7 more
openalex +1 more source
Advanced Science, EarlyView.Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells
, 2010 Thilo Welsch +6 more
openalex +2 more sources
NO to Lysosomes: A Signal for Insulin Resistance in Obesity [PDF]
, 2019 Ali Javaheri, Abhinav Diwan
openalex +1 more source
Nanoscale Mapping of the Subcellular Glycosylation Landscape
Advanced Science, EarlyView.Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter +4 more
wiley +1 more source
Advanced Science, EarlyView.PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
MoleculesIn this study, twenty-four new furoxan and seco-coumarin hybrids were synthesized, and their antiproliferative activities against four breast cancer cells (MCF-7/ADR, MCF-7, MDA-MB-231, and MDA-MB-468) were evaluated.
Feng Qu +7 more
doaj +1 more source
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells [PDF]
, 2018 Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS is a phenomenon that results from
Benitez-Martin, Carlos +4 more
core
A novel lysosome-related prognostic signature associated with prognosis and immune infiltration landscape in oral squamous cell carcinoma [PDF]
Jingjing Liu +4 more
openalex +1 more source