Results 11 to 20 of about 9,882 (257)

Assessing Rabies Vaccine Protection against a Novel Lyssavirus, Kotalahti Bat Lyssavirus [PDF]

Viruses, 2021
Rabies is a fatal encephalitis caused by an important group of viruses within the Lyssavirus genus. The prototype virus, rabies virus, is still the most commonly reported lyssavirus and causes approximately 59,000 human fatalities annually. The human and
Rebecca Shipley, Edward Wright, Fabian Z. X. Lean, David Selden, Daniel L. Horton, Anthony R. Fooks, Ashley C. Banyard   +6 more
doaj   +5 more sources

The Challenge of Lyssavirus Infections in Domestic and Other Animals: A Mix of Virological Confusion, Consternation, Chagrin, and Curiosity. [PDF]

Pathogens
Lyssaviruses are RNA viruses in the Family Rhabdoviridae, Genus Lyssavirus. They represent the causative agents of acute, progressive encephalitis, known historically as rabies.
Rupprecht CE, Belsare AV, Cliquet F, Mshelbwala PP, Seetahal JFR, Wicker VV.   +5 more
europepmc   +4 more sources

Toward the Development of a Pan-Lyssavirus Vaccine [PDF]

Viruses
In addition to the rabies virus (RABV), 16 more lyssavirus species have been identified worldwide, causing a disease similar to RABV. Non-rabies-related human deaths have been described, but the number of cases is unknown, and the potential of such ...
Sabrine Ben Hamed, Jacob F. Myers, Anisha Chandwani, Christoph Wirblich, Drishya Kurup, Nir Paran, Matthias J. Schnell   +6 more
doaj   +3 more sources

Ikoma Lyssavirus, Highly Divergent Novel Lyssavirus in an African Civet

Emerging Infectious Diseases, 2012
Evidence in support of a novel lyssavirus was obtained from brain samples of an African civet in Tanzania. Results of phylogenetic analysis of nucleoprotein gene sequences from representative Lyssavirus species and this novel lyssavirus provided strong ...
Denise A. Marston, Daniel L. Horton, Chanasa Ngeleja, Katie Hampson, Lorraine M. McElhinney, Ashley C. Banyard, Daniel Haydon, Sarah Cleaveland, Charles E. Rupprecht, Machunde Bigambo, Anthony R. Fooks, Tiziana Lembo   +11 more
doaj   +5 more sources

Comparison of Pan-Lyssavirus RT-PCRs and Development of an Improved Protocol for Surveillance of Non-RABV Lyssaviruses

Viruses, 2023
Rabies is a zoonotic and fatal encephalitis caused by members of the Lyssavirus genus. Among them, the most relevant species is Lyssavirus rabies, which is estimated to cause 60,000 human and most mammal rabies deaths annually worldwide.
Petra Drzewnioková, Sabrina Marciano, Stefania Leopardi, Valentina Panzarin, Paola De Benedictis   +4 more
doaj   +2 more sources

Discovery of a novel bat lyssavirus in a Long-fingered bat (Myotis capaccinii) from Slovenia.

PLoS Neglected Tropical Diseases, 2023
Lyssaviruses are the causative agents of rabies, a zoonotic, fatal disease that is thought to be ancestral to bats. In the last decade, the detection of bat associated lyssaviruses is increasing also in Europe.
Danijela Černe, Peter Hostnik, Ivan Toplak, Primož Presetnik, Jedrt Maurer-Wernig, Urška Kuhar   +5 more
doaj   +2 more sources

Novel Lyssavirus in Bat, Spain

Emerging Infectious Diseases, 2013
A new tentative lyssavirus, Lleida bat lyssavirus, was found in a bent-winged bat (Miniopterus schreibersii) in Spain. It does not belong to phylogroups I or II, and it seems to be more closely related to the West Causasian bat virus, and especially to ...
Nidia Aréchiga Ceballos, Sonia Vázquez Morón, José M. Berciano, Olga Nicolás, Carolina Aznar López, Javier Juste, Cristina Rodríguez Nevado, Álvaro Aguilar Setién, Juan E. Echevarría   +8 more
doaj   +5 more sources

Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies lyssavirus neutralizing antibodies.

PLoS Neglected Tropical Diseases, 2022
Neutralizing antibodies (nAbs) prevent the entry of viruses into permissive cells. Since nAbs represent correlates of protection against the Rabies lyssavirus, the presence of sufficient nAbs indicates effective vaccination.
Lara Schöler, Vu Thuy Khanh Le-Trilling, Ulf Dittmer, Melanie Fiedler, Mirko Trilling   +4 more
doaj   +2 more sources

Lyssavirus matrix protein inhibits NLRP3 inflammasome assembly by binding to NLRP3

Cell Reports
Summary: Lyssavirus is a kind of neurotropic pathogen that needs to evade peripheral host immunity to enter the central nervous system to accomplish infection.
Baokun Sui, Jianqing Zhao, Jinxiao Wang, Jiaxin Zheng, Rui Zhou, Di Wu, Zonghui Zeng, Yueming Yuan, Zhenfang Fu, Ling Zhao, Ming Zhou   +10 more
doaj   +2 more sources

Transcriptomic responses of bat cells to European bat lyssavirus 1 infection under conditions simulating euthermia and hibernation

BMC Immunology, 2023
Background Coevolution between pathogens and their hosts decreases host morbidity and mortality. Bats host and can tolerate viruses which can be lethal to other vertebrate orders, including humans.
Markéta Harazim, Juliette Perrot, Hugo Varet, Hervé Bourhy, Julien Lannoy, Jiri Pikula, Veronika Seidlová, Laurent Dacheux, Natália Martínková   +8 more
doaj   +2 more sources