Results 11 to 20 of about 9,235 (254)

Toward the Development of a Pan-Lyssavirus Vaccine [PDF]

Viruses
In addition to the rabies virus (RABV), 16 more lyssavirus species have been identified worldwide, causing a disease similar to RABV. Non-rabies-related human deaths have been described, but the number of cases is unknown, and the potential of such ...
Sabrine Ben Hamed, Jacob F. Myers, Anisha Chandwani, Christoph Wirblich, Drishya Kurup, Nir Paran, Matthias J. Schnell   +6 more
doaj   +5 more sources

Assessing Rabies Vaccine Protection against a Novel Lyssavirus, Kotalahti Bat Lyssavirus [PDF]

Viruses, 2021
Rabies is a fatal encephalitis caused by an important group of viruses within the Lyssavirus genus. The prototype virus, rabies virus, is still the most commonly reported lyssavirus and causes approximately 59,000 human fatalities annually. The human and
Rebecca Shipley, Edward Wright, Fabian Z. X. Lean, David Selden, Daniel L. Horton, Anthony R. Fooks, Ashley C. Banyard   +6 more
doaj   +6 more sources

TRIM72 restricts lyssavirus infection by inducing K48-linked ubiquitination and proteasome degradation of the matrix protein. [PDF]

PLoS Pathogens, 2023
The tripartite motif (TRIM) protein family is the largest subfamily of E3 ubiquitin ligases, playing a crucial role in the antiviral process. In this study, we found that TRIM72, a member of the TRIM protein family, was increased in neuronal cells and ...
Baokun Sui, Jiaxin Zheng, Zhenfang Fu, Ling Zhao, Ming Zhou   +4 more
doaj   +3 more sources

Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex. [PDF]

Viruses, 2023
Australian bat lyssavirus (ABLV) shows similar clinical symptoms as rabies, but there are currently no protein structures available for ABLV proteins. In lyssaviruses, the interaction between nucleoprotein (N) and phosphoprotein (N) in the absence of RNA
Donnelly CM, Stewart M, Roby JA, Sundaramoorthy V, Forwood JK.   +4 more
europepmc   +4 more sources

Comparison of Pan-Lyssavirus RT-PCRs and Development of an Improved Protocol for Surveillance of Non-RABV Lyssaviruses

Viruses, 2023
Rabies is a zoonotic and fatal encephalitis caused by members of the Lyssavirus genus. Among them, the most relevant species is Lyssavirus rabies, which is estimated to cause 60,000 human and most mammal rabies deaths annually worldwide.
Petra Drzewnioková, Sabrina Marciano, Stefania Leopardi, Valentina Panzarin, Paola De Benedictis   +4 more
doaj   +2 more sources

Discovery of a novel bat lyssavirus in a Long-fingered bat (Myotis capaccinii) from Slovenia.

PLoS Neglected Tropical Diseases, 2023
Lyssaviruses are the causative agents of rabies, a zoonotic, fatal disease that is thought to be ancestral to bats. In the last decade, the detection of bat associated lyssaviruses is increasing also in Europe.
Danijela Černe, Peter Hostnik, Ivan Toplak, Primož Presetnik, Jedrt Maurer-Wernig, Urška Kuhar   +5 more
doaj   +2 more sources

A case report of a cat infected with European bat lyssavirus type 1, the Netherlands, October 2024. [PDF]

Euro Surveill
In October 2024, an infection of European bat lyssavirus type 1 was confirmed in a domestic cat in the Netherlands. Several weeks before, the owners had found a dead bat considered to be caught by the cat.
Eblé P, Dekker A, van den End S, Visser V, Engelsma M, Harders F, van Keulen L, van Weezep E, Holwerda M.   +8 more
europepmc   +3 more sources

Novel Lyssavirus in Bat, Spain [PDF]

Emerging Infectious Diseases, 2013
A new tentative lyssavirus, Lleida bat lyssavirus, was found in a bent-winged bat (Miniopterus schreibersii) in Spain. It does not belong to phylogroups I or II, and it seems to be more closely related to the West Causasian bat virus, and especially to ...
Nidia Aréchiga Ceballos, Sonia Vázquez Morón, José M. Berciano, Olga Nicolás, Carolina Aznar López, Javier Juste, Cristina Rodríguez Nevado, Álvaro Aguilar Setién, Juan E. Echevarría   +8 more
doaj   +5 more sources

European distribution and intramuscular pathogenicity of divergent lyssaviruses West Caucasian bat virus and Lleida bat lyssavirus. [PDF]

iScience
Leopardi S, Dacheux L, Serra-Cobo J, Ábrahám Á, Bajić B, Bourhy H, Bücs SL, Budinski I, Castellan M, Drzewniokova P, Dundarova H, Festa F, Kergoat L, Leuchtmann M, López-Roig M, Pontier D, Priore MF, Robardet E, Scaravelli D, Zecchin B, Lanszki Z, Görföl T, Kemenesi G, De Benedictis P.   +23 more
europepmc   +3 more sources

Establishment and clinical validation of an in-cell-ELISA-based assay for the rapid quantification of Rabies lyssavirus neutralizing antibodies.

PLoS Neglected Tropical Diseases, 2022
Neutralizing antibodies (nAbs) prevent the entry of viruses into permissive cells. Since nAbs represent correlates of protection against the Rabies lyssavirus, the presence of sufficient nAbs indicates effective vaccination.
Lara Schöler, Vu Thuy Khanh Le-Trilling, Ulf Dittmer, Melanie Fiedler, Mirko Trilling   +4 more
doaj   +2 more sources